SlideShare a Scribd company logo
1 of 14
 VIRAL infections:-
◦ Adenovirus
◦ Measles
◦ EBV
◦ CMV
 Bacterial infections
◦ Scarlet fever
◦ Leptospirosis
◦ RMSF
◦ meningococcemia
 Rheumatologic disease
◦ Behcet disease
◦ SOJIA
 Others
◦ TSS
◦ SSSS
◦ Drug hypersensitivity reactions
◦ SJS
 Incubation Period: 3-8 days1
 Common presentation:
◦ rapidly rising temp. >35oC
◦ severe headache, retro-orbital pain, myalgia,
arthralgia, nausea, and/or vomiting
◦ Hepatomegaly +/- splenomegaly
◦ hemorrhagic manifestations such as petechiae,
epistaxis, and gingival bleeding occur in some
patients.
1. Ligon BL. Dengue fever and Dengue Hemorrhagic fever: A review of history,
transmission, treatment and prevention. Semin Pediatr Infect Dis. 2004;16:60–
5.
 Days of fever: 5 to 6 days, bi phasic
◦ Fever that lasts>10 days is probably not due to
dengue
◦ Of patients with dengue hemorrhagic fever, 90% are
younger than 15 years. 2
2. https://emedicine.medscape.com/article/215840-clinical
 Rash:
◦ The initial rash is a transient flushing erythema of face
that typically occurs shortly before or within the first
24-48 hours of the onset of symptoms and is thought
to be the result of capillary dilatation.
◦ The typical rash begins on day 3 and persists 2-3 days.
◦ More than 50% of infected patients report having a rash
during this period that initially is macular or
maculopapular and becomes diffusely erythematous3
◦ The generalized rash characteristically starts on the
dorsum of the hands and feet and spreads to the arms,
legs, and torso and it lasts for several days and
subsides without desquamation.
◦ The morbilliform, maculopapular rash usually spares
palms and soles, and mostly subsides without
desquamation.
3. World Health Organization. Dengue fever in Indonesia. Available
from:http://www.who.int/csr/don/2004_02_26a/en/index.html [last accessed
 Incubation period
◦ 1-2 weeks
 Common presentation
◦ Fever is abrupt onset, High grade, a/w myalgia,
headache & arthralgia
◦ Rash
◦ Hepatosplenomegaly and lymphadenopathy
◦ Edema
Narayanasamy DK, Arunagirinathan AK, Kumar RK, Raghavendran VD. Clinico -
laboratory profile of scrub typhus - An emerging rickettsiosis in India. Indian J
 Rash
◦ SFG: appears on 2nd -5th day of illness, can be
pruritic, evolving: macular, maculopapular,
petechial, purpuric or gangrenous
◦ Centripetal spread
◦ Can involve palms and soles: typical of rickettsia
◦ ESCHAR: crusty necrotic lesion with or without
surrounding erythematous halo, suggest location of
vector bite.
◦ it is non pruritic, painless, about 1 cm, usually
single, a/w regional lymphadenopathy; uncommon
in SFG, more common in scrub tyhus
 Days of fever
◦ Generally more than 5 days
◦ 3 to 4 weeks
 Incubation: 1-7 days
 Presentation:
◦ Sore throat, painful swallowing
◦ Fever - typically over 39 °C (102.2 °F)
◦ Fatigue
◦ Enlarged and reddened tonsils with yellow or white
exudates present (this is typically an exudative
pharyngitis)
◦ Enlarged and tender lymph nodes usually located
on the front of the neck
Goldsmith, Lowell; Katz, Stephen; Gilchrist, Barbara; Paller, Amy; Leffell, David;
Wolff, Klaus (2012). Fitzpatrick's Dermatology in General Medicine. McGraw Hill.
^ Jump up to:a b c d e f Usatine, Richard (2013). Color Atlas of Family Medicine,
Second Edition. McGraw Hill Companies.
 Rash
◦ Begins 1-2 days after onset of symptoms of strep
pharyngitis
◦ “scarlantiform” :diffuse redness of skin with small
papules, or bumps, which resemble goose pimples;
can be itchy, blanchable but not painful
◦ First appears on trunk and then spreads to arms
and thighs
◦ Face, palms and soles are usually uninvolved
◦ Palate: forscheimer spots
◦ Rash fades in 3 to 4 days followed by desquamation
of the rash which will last several weeks to a month
 Duration of fever
◦ 5 to 10 days, if not complicated.
Red cheeks
and pale area
around the
mouth in
scarlet fever
The rash of scarlet fever
Infection Common presentation Days of Fever Rash
Dengue Bi phasic break bone fever
Hypotension
hemorrhage
<7 days
Rickettsia Similar to dengue fever
With persistent intractable
headache
With rash and eschar
Toxic, confusion delirium
GI symptoms+
Can be
prolonged upto
4 weeks
Scarlet Sore throat
Fever rash
Enlarged tonsils
Enlarged LN
<7 days
KAWASAKI
DISEASE
High persistent fever not
responsive to PCM
Non purulent
conjunctivitis
Unilateral cervical LN+
Rash
Edema
1-2 weeks high
grade fever,
subacute upto
6 weeks

More Related Content

What's hot (20)

Measles
MeaslesMeasles
Measles
 
Disease case studies
Disease case studiesDisease case studies
Disease case studies
 
Dengue disease ppt
Dengue disease pptDengue disease ppt
Dengue disease ppt
 
Chickenpox thanks
Chickenpox thanksChickenpox thanks
Chickenpox thanks
 
8 measles
8 measles8 measles
8 measles
 
Measles, mumps and rubella
Measles, mumps and rubellaMeasles, mumps and rubella
Measles, mumps and rubella
 
Bejar, malaika
Bejar, malaikaBejar, malaika
Bejar, malaika
 
Chickenpox
ChickenpoxChickenpox
Chickenpox
 
Dengue fever
Dengue feverDengue fever
Dengue fever
 
AIDS
AIDSAIDS
AIDS
 
Chicken Pox
Chicken PoxChicken Pox
Chicken Pox
 
Dengue fever
Dengue feverDengue fever
Dengue fever
 
Rubella
RubellaRubella
Rubella
 
chicken pox
    chicken pox    chicken pox
chicken pox
 
Measles
MeaslesMeasles
Measles
 
Chickenpox
ChickenpoxChickenpox
Chickenpox
 
Chickenpox
ChickenpoxChickenpox
Chickenpox
 
Lec4 measles, mumps, rubella, small pox & ulcer
Lec4 measles, mumps, rubella, small pox & ulcerLec4 measles, mumps, rubella, small pox & ulcer
Lec4 measles, mumps, rubella, small pox & ulcer
 
Chickenpox
ChickenpoxChickenpox
Chickenpox
 
Syphilis
SyphilisSyphilis
Syphilis
 

Similar to Kawasaki the the big kwestion

Similar to Kawasaki the the big kwestion (20)

Dengue fever 2020
Dengue fever 2020Dengue fever 2020
Dengue fever 2020
 
Chikungunya
Chikungunya Chikungunya
Chikungunya
 
Dengue and chickungunya
Dengue and chickungunyaDengue and chickungunya
Dengue and chickungunya
 
Dengue ppt
Dengue pptDengue ppt
Dengue ppt
 
Degue fever
Degue feverDegue fever
Degue fever
 
Dengue and chikungunya in Children
Dengue and chikungunya in ChildrenDengue and chikungunya in Children
Dengue and chikungunya in Children
 
dengue.pptx
dengue.pptxdengue.pptx
dengue.pptx
 
Dengue
DengueDengue
Dengue
 
Dengue hemorrhagic fever
Dengue hemorrhagic feverDengue hemorrhagic fever
Dengue hemorrhagic fever
 
25221.ppt
25221.ppt25221.ppt
25221.ppt
 
25221 (1).ppt
25221 (1).ppt25221 (1).ppt
25221 (1).ppt
 
denguefever-160329120436.pptx
denguefever-160329120436.pptxdenguefever-160329120436.pptx
denguefever-160329120436.pptx
 
Fever with rash in dermatology.
Fever with rash in dermatology.Fever with rash in dermatology.
Fever with rash in dermatology.
 
Dengue Fever
Dengue FeverDengue Fever
Dengue Fever
 
Dengue
DengueDengue
Dengue
 
Dengue fever
Dengue feverDengue fever
Dengue fever
 
F E V E R A N D S K I N R A S H Final
F E V E R  A N D  S K I N  R A S H FinalF E V E R  A N D  S K I N  R A S H Final
F E V E R A N D S K I N R A S H Final
 
Dengue
DengueDengue
Dengue
 
Dengue
DengueDengue
Dengue
 
Dengue fever ppt
Dengue fever pptDengue fever ppt
Dengue fever ppt
 

Recently uploaded

Ernakulam Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Ernakulam Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real MeetErnakulam Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Ernakulam Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real MeetCall Girls Chandigarh
 
(Sonam Bajaj) Call Girl in Jaipur- 09257276172 Escorts Service 50% Off with C...
(Sonam Bajaj) Call Girl in Jaipur- 09257276172 Escorts Service 50% Off with C...(Sonam Bajaj) Call Girl in Jaipur- 09257276172 Escorts Service 50% Off with C...
(Sonam Bajaj) Call Girl in Jaipur- 09257276172 Escorts Service 50% Off with C...indiancallgirl4rent
 
nagpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
nagpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meetnagpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
nagpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real MeetCall Girls Service
 
raisen Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
raisen Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meetraisen Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
raisen Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real MeetCall Girls Service
 
Jaipur Call Girls 9257276172 Call Girl in Jaipur Rajasthan
Jaipur Call Girls 9257276172 Call Girl in Jaipur RajasthanJaipur Call Girls 9257276172 Call Girl in Jaipur Rajasthan
Jaipur Call Girls 9257276172 Call Girl in Jaipur Rajasthanindiancallgirl4rent
 
Enjoyment ★ 8854095900 Indian Call Girls In Dehradun 🍆🍌 By Dehradun Call Girl ★
Enjoyment ★ 8854095900 Indian Call Girls In Dehradun 🍆🍌 By Dehradun Call Girl ★Enjoyment ★ 8854095900 Indian Call Girls In Dehradun 🍆🍌 By Dehradun Call Girl ★
Enjoyment ★ 8854095900 Indian Call Girls In Dehradun 🍆🍌 By Dehradun Call Girl ★indiancallgirl4rent
 
Call Girls Thane Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Thane Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Thane Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Thane Just Call 9907093804 Top Class Call Girl Service AvailableDipal Arora
 
VIP Call Girl Sector 10 Noida Call Me: 9711199171
VIP Call Girl Sector 10 Noida Call Me: 9711199171VIP Call Girl Sector 10 Noida Call Me: 9711199171
VIP Call Girl Sector 10 Noida Call Me: 9711199171Call Girls Service Gurgaon
 
Krishnagiri call girls Tamil aunty 7877702510
Krishnagiri call girls Tamil aunty 7877702510Krishnagiri call girls Tamil aunty 7877702510
Krishnagiri call girls Tamil aunty 7877702510Vipesco
 
Chandigarh Call Girls 👙 7001035870 👙 Genuine WhatsApp Number for Real Meet
Chandigarh Call Girls 👙 7001035870 👙 Genuine WhatsApp Number for Real MeetChandigarh Call Girls 👙 7001035870 👙 Genuine WhatsApp Number for Real Meet
Chandigarh Call Girls 👙 7001035870 👙 Genuine WhatsApp Number for Real Meetpriyashah722354
 
(Deeksha) 💓 9920725232 💓High Profile Call Girls Navi Mumbai You Can Get The S...
(Deeksha) 💓 9920725232 💓High Profile Call Girls Navi Mumbai You Can Get The S...(Deeksha) 💓 9920725232 💓High Profile Call Girls Navi Mumbai You Can Get The S...
(Deeksha) 💓 9920725232 💓High Profile Call Girls Navi Mumbai You Can Get The S...Ahmedabad Call Girls
 
VIP Call Girl Sector 88 Gurgaon Delhi Just Call Me 9899900591
VIP Call Girl Sector 88 Gurgaon Delhi Just Call Me 9899900591VIP Call Girl Sector 88 Gurgaon Delhi Just Call Me 9899900591
VIP Call Girl Sector 88 Gurgaon Delhi Just Call Me 9899900591adityaroy0215
 
Sambalpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Sambalpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real MeetSambalpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Sambalpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real MeetCall Girls Service
 
Chandigarh Escorts, 😋9988299661 😋50% off at Escort Service in Chandigarh
Chandigarh Escorts, 😋9988299661 😋50% off at Escort Service in ChandigarhChandigarh Escorts, 😋9988299661 😋50% off at Escort Service in Chandigarh
Chandigarh Escorts, 😋9988299661 😋50% off at Escort Service in ChandigarhSheetaleventcompany
 
Call Girl Gorakhpur * 8250192130 Service starts from just ₹9999 ✅
Call Girl Gorakhpur * 8250192130 Service starts from just ₹9999 ✅Call Girl Gorakhpur * 8250192130 Service starts from just ₹9999 ✅
Call Girl Gorakhpur * 8250192130 Service starts from just ₹9999 ✅gragmanisha42
 
Call Girl In Zirakpur ❤️♀️@ 9988299661 Zirakpur Call Girls Near Me ❤️♀️@ Sexy...
Call Girl In Zirakpur ❤️♀️@ 9988299661 Zirakpur Call Girls Near Me ❤️♀️@ Sexy...Call Girl In Zirakpur ❤️♀️@ 9988299661 Zirakpur Call Girls Near Me ❤️♀️@ Sexy...
Call Girl In Zirakpur ❤️♀️@ 9988299661 Zirakpur Call Girls Near Me ❤️♀️@ Sexy...Sheetaleventcompany
 
❤️♀️@ Jaipur Call Girls ❤️♀️@ Jaispreet Call Girl Services in Jaipur QRYPCF ...
❤️♀️@ Jaipur Call Girls ❤️♀️@ Jaispreet Call Girl Services in Jaipur QRYPCF  ...❤️♀️@ Jaipur Call Girls ❤️♀️@ Jaispreet Call Girl Services in Jaipur QRYPCF  ...
❤️♀️@ Jaipur Call Girls ❤️♀️@ Jaispreet Call Girl Services in Jaipur QRYPCF ...Gfnyt.com
 
Call Girls Patiala Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Patiala Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Patiala Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Patiala Just Call 9907093804 Top Class Call Girl Service AvailableDipal Arora
 
Muzaffarpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Muzaffarpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real MeetMuzaffarpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Muzaffarpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real MeetCall Girls Service
 
Call Girls Service Anantapur 📲 6297143586 Book Now VIP Call Girls in Anantapur
Call Girls Service Anantapur 📲 6297143586 Book Now VIP Call Girls in AnantapurCall Girls Service Anantapur 📲 6297143586 Book Now VIP Call Girls in Anantapur
Call Girls Service Anantapur 📲 6297143586 Book Now VIP Call Girls in Anantapurgragmanisha42
 

Recently uploaded (20)

Ernakulam Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Ernakulam Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real MeetErnakulam Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Ernakulam Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
 
(Sonam Bajaj) Call Girl in Jaipur- 09257276172 Escorts Service 50% Off with C...
(Sonam Bajaj) Call Girl in Jaipur- 09257276172 Escorts Service 50% Off with C...(Sonam Bajaj) Call Girl in Jaipur- 09257276172 Escorts Service 50% Off with C...
(Sonam Bajaj) Call Girl in Jaipur- 09257276172 Escorts Service 50% Off with C...
 
nagpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
nagpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meetnagpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
nagpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
 
raisen Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
raisen Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meetraisen Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
raisen Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
 
Jaipur Call Girls 9257276172 Call Girl in Jaipur Rajasthan
Jaipur Call Girls 9257276172 Call Girl in Jaipur RajasthanJaipur Call Girls 9257276172 Call Girl in Jaipur Rajasthan
Jaipur Call Girls 9257276172 Call Girl in Jaipur Rajasthan
 
Enjoyment ★ 8854095900 Indian Call Girls In Dehradun 🍆🍌 By Dehradun Call Girl ★
Enjoyment ★ 8854095900 Indian Call Girls In Dehradun 🍆🍌 By Dehradun Call Girl ★Enjoyment ★ 8854095900 Indian Call Girls In Dehradun 🍆🍌 By Dehradun Call Girl ★
Enjoyment ★ 8854095900 Indian Call Girls In Dehradun 🍆🍌 By Dehradun Call Girl ★
 
Call Girls Thane Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Thane Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Thane Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Thane Just Call 9907093804 Top Class Call Girl Service Available
 
VIP Call Girl Sector 10 Noida Call Me: 9711199171
VIP Call Girl Sector 10 Noida Call Me: 9711199171VIP Call Girl Sector 10 Noida Call Me: 9711199171
VIP Call Girl Sector 10 Noida Call Me: 9711199171
 
Krishnagiri call girls Tamil aunty 7877702510
Krishnagiri call girls Tamil aunty 7877702510Krishnagiri call girls Tamil aunty 7877702510
Krishnagiri call girls Tamil aunty 7877702510
 
Chandigarh Call Girls 👙 7001035870 👙 Genuine WhatsApp Number for Real Meet
Chandigarh Call Girls 👙 7001035870 👙 Genuine WhatsApp Number for Real MeetChandigarh Call Girls 👙 7001035870 👙 Genuine WhatsApp Number for Real Meet
Chandigarh Call Girls 👙 7001035870 👙 Genuine WhatsApp Number for Real Meet
 
(Deeksha) 💓 9920725232 💓High Profile Call Girls Navi Mumbai You Can Get The S...
(Deeksha) 💓 9920725232 💓High Profile Call Girls Navi Mumbai You Can Get The S...(Deeksha) 💓 9920725232 💓High Profile Call Girls Navi Mumbai You Can Get The S...
(Deeksha) 💓 9920725232 💓High Profile Call Girls Navi Mumbai You Can Get The S...
 
VIP Call Girl Sector 88 Gurgaon Delhi Just Call Me 9899900591
VIP Call Girl Sector 88 Gurgaon Delhi Just Call Me 9899900591VIP Call Girl Sector 88 Gurgaon Delhi Just Call Me 9899900591
VIP Call Girl Sector 88 Gurgaon Delhi Just Call Me 9899900591
 
Sambalpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Sambalpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real MeetSambalpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Sambalpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
 
Chandigarh Escorts, 😋9988299661 😋50% off at Escort Service in Chandigarh
Chandigarh Escorts, 😋9988299661 😋50% off at Escort Service in ChandigarhChandigarh Escorts, 😋9988299661 😋50% off at Escort Service in Chandigarh
Chandigarh Escorts, 😋9988299661 😋50% off at Escort Service in Chandigarh
 
Call Girl Gorakhpur * 8250192130 Service starts from just ₹9999 ✅
Call Girl Gorakhpur * 8250192130 Service starts from just ₹9999 ✅Call Girl Gorakhpur * 8250192130 Service starts from just ₹9999 ✅
Call Girl Gorakhpur * 8250192130 Service starts from just ₹9999 ✅
 
Call Girl In Zirakpur ❤️♀️@ 9988299661 Zirakpur Call Girls Near Me ❤️♀️@ Sexy...
Call Girl In Zirakpur ❤️♀️@ 9988299661 Zirakpur Call Girls Near Me ❤️♀️@ Sexy...Call Girl In Zirakpur ❤️♀️@ 9988299661 Zirakpur Call Girls Near Me ❤️♀️@ Sexy...
Call Girl In Zirakpur ❤️♀️@ 9988299661 Zirakpur Call Girls Near Me ❤️♀️@ Sexy...
 
❤️♀️@ Jaipur Call Girls ❤️♀️@ Jaispreet Call Girl Services in Jaipur QRYPCF ...
❤️♀️@ Jaipur Call Girls ❤️♀️@ Jaispreet Call Girl Services in Jaipur QRYPCF  ...❤️♀️@ Jaipur Call Girls ❤️♀️@ Jaispreet Call Girl Services in Jaipur QRYPCF  ...
❤️♀️@ Jaipur Call Girls ❤️♀️@ Jaispreet Call Girl Services in Jaipur QRYPCF ...
 
Call Girls Patiala Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Patiala Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Patiala Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Patiala Just Call 9907093804 Top Class Call Girl Service Available
 
Muzaffarpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Muzaffarpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real MeetMuzaffarpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Muzaffarpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
 
Call Girls Service Anantapur 📲 6297143586 Book Now VIP Call Girls in Anantapur
Call Girls Service Anantapur 📲 6297143586 Book Now VIP Call Girls in AnantapurCall Girls Service Anantapur 📲 6297143586 Book Now VIP Call Girls in Anantapur
Call Girls Service Anantapur 📲 6297143586 Book Now VIP Call Girls in Anantapur
 

Kawasaki the the big kwestion

  • 1.
  • 2.  VIRAL infections:- ◦ Adenovirus ◦ Measles ◦ EBV ◦ CMV  Bacterial infections ◦ Scarlet fever ◦ Leptospirosis ◦ RMSF ◦ meningococcemia  Rheumatologic disease ◦ Behcet disease ◦ SOJIA  Others ◦ TSS ◦ SSSS ◦ Drug hypersensitivity reactions ◦ SJS
  • 3.  Incubation Period: 3-8 days1  Common presentation: ◦ rapidly rising temp. >35oC ◦ severe headache, retro-orbital pain, myalgia, arthralgia, nausea, and/or vomiting ◦ Hepatomegaly +/- splenomegaly ◦ hemorrhagic manifestations such as petechiae, epistaxis, and gingival bleeding occur in some patients. 1. Ligon BL. Dengue fever and Dengue Hemorrhagic fever: A review of history, transmission, treatment and prevention. Semin Pediatr Infect Dis. 2004;16:60– 5.
  • 4.  Days of fever: 5 to 6 days, bi phasic ◦ Fever that lasts>10 days is probably not due to dengue ◦ Of patients with dengue hemorrhagic fever, 90% are younger than 15 years. 2 2. https://emedicine.medscape.com/article/215840-clinical
  • 5.  Rash: ◦ The initial rash is a transient flushing erythema of face that typically occurs shortly before or within the first 24-48 hours of the onset of symptoms and is thought to be the result of capillary dilatation. ◦ The typical rash begins on day 3 and persists 2-3 days. ◦ More than 50% of infected patients report having a rash during this period that initially is macular or maculopapular and becomes diffusely erythematous3 ◦ The generalized rash characteristically starts on the dorsum of the hands and feet and spreads to the arms, legs, and torso and it lasts for several days and subsides without desquamation. ◦ The morbilliform, maculopapular rash usually spares palms and soles, and mostly subsides without desquamation. 3. World Health Organization. Dengue fever in Indonesia. Available from:http://www.who.int/csr/don/2004_02_26a/en/index.html [last accessed
  • 6.
  • 7.
  • 8.
  • 9.  Incubation period ◦ 1-2 weeks  Common presentation ◦ Fever is abrupt onset, High grade, a/w myalgia, headache & arthralgia ◦ Rash ◦ Hepatosplenomegaly and lymphadenopathy ◦ Edema Narayanasamy DK, Arunagirinathan AK, Kumar RK, Raghavendran VD. Clinico - laboratory profile of scrub typhus - An emerging rickettsiosis in India. Indian J
  • 10.  Rash ◦ SFG: appears on 2nd -5th day of illness, can be pruritic, evolving: macular, maculopapular, petechial, purpuric or gangrenous ◦ Centripetal spread ◦ Can involve palms and soles: typical of rickettsia ◦ ESCHAR: crusty necrotic lesion with or without surrounding erythematous halo, suggest location of vector bite. ◦ it is non pruritic, painless, about 1 cm, usually single, a/w regional lymphadenopathy; uncommon in SFG, more common in scrub tyhus  Days of fever ◦ Generally more than 5 days ◦ 3 to 4 weeks
  • 11.  Incubation: 1-7 days  Presentation: ◦ Sore throat, painful swallowing ◦ Fever - typically over 39 °C (102.2 °F) ◦ Fatigue ◦ Enlarged and reddened tonsils with yellow or white exudates present (this is typically an exudative pharyngitis) ◦ Enlarged and tender lymph nodes usually located on the front of the neck Goldsmith, Lowell; Katz, Stephen; Gilchrist, Barbara; Paller, Amy; Leffell, David; Wolff, Klaus (2012). Fitzpatrick's Dermatology in General Medicine. McGraw Hill. ^ Jump up to:a b c d e f Usatine, Richard (2013). Color Atlas of Family Medicine, Second Edition. McGraw Hill Companies.
  • 12.  Rash ◦ Begins 1-2 days after onset of symptoms of strep pharyngitis ◦ “scarlantiform” :diffuse redness of skin with small papules, or bumps, which resemble goose pimples; can be itchy, blanchable but not painful ◦ First appears on trunk and then spreads to arms and thighs ◦ Face, palms and soles are usually uninvolved ◦ Palate: forscheimer spots ◦ Rash fades in 3 to 4 days followed by desquamation of the rash which will last several weeks to a month  Duration of fever ◦ 5 to 10 days, if not complicated.
  • 13. Red cheeks and pale area around the mouth in scarlet fever The rash of scarlet fever
  • 14. Infection Common presentation Days of Fever Rash Dengue Bi phasic break bone fever Hypotension hemorrhage <7 days Rickettsia Similar to dengue fever With persistent intractable headache With rash and eschar Toxic, confusion delirium GI symptoms+ Can be prolonged upto 4 weeks Scarlet Sore throat Fever rash Enlarged tonsils Enlarged LN <7 days KAWASAKI DISEASE High persistent fever not responsive to PCM Non purulent conjunctivitis Unilateral cervical LN+ Rash Edema 1-2 weeks high grade fever, subacute upto 6 weeks