mathwork product for computational biology (genbank embl ncbi blast pdb)

1. MATHWORKS PRODUCT FOR
COMPUTATIONAL BIOLOGY
GENBANK
EMBL
NCBI BLAST
PDB.
-VJ

2. MATH WORK and COMPUTATIONAL
BIOLOGY
 Mathwork is an american privately held
corporation that specializes in mathematical
computing software.
 Computational biology involves the development
and application of data-analytical and theoretical
methods, mathematical modeling
and computational simulation techniques to the
study of biological, behavioral, and social systems.

3. GEN BANK
The GenBank sequence database is an open
access annotated collection of all publicly
available nucleotide sequence and their
protein translations.
 Genbank is built and distributed by the
National center for biology information(NCBI)
a division of the national library of medicine.

4.  NCBI builds GenBank primarily from the submission of
sequence data from authors and from the bulk
submission of expressed sequence tag (EST).
 Genome survey sequence (GSS) and other high-
throughput data from sequencing centers .
Database collaboration, which comprise the
DNA Databank of Japan (DDBJ)
European Nucleotide Archive (ENA)
GenBank at NCBI.
https://www.ncbi.nlm.nih.gov/genbank/

5. EMBL
 European Molecular Biology Laboratory(EMBL).
 At EMBL-EBI, they make the world’s public biological
data freely available to the scientific community via a
range of services and tools, perform basic
research and provide professional training in
bioinformatics.
 They maintain the world’s most comprehensive range
of freely available molecular data resources.

6.  Developed in collaboration with our colleagues
worldwide, our databases and tools help scientists
share data efficiently, perform complex queries and
analyse the results in different ways.
 Our work supports millions of researchers, who are
wet-lab and computational biologists working in all
areas of the life sciences, from biomedicine to
biodiversity and agri-food research.
 https://www.ebi.ac.uk

7. NCBI BLAST
 BLAST for Basic Local Alignment Search Tool is
an algorithm for comparing primary biological
sequence information, such as the amino-acid
sequences of proteins or nucleotides of the
DNA sequences.
 BLAST is one of the most widely used
bioinformatics programs for sequence searching.
https://blast.ncbi.nlm.nih.gov/Blast.cgi?PROGRA
M=blastn&PAGE_TYPE=BlastSearch&LINK_LOC=
blasthome

8. PDB (protein Data bank)
The main function of this database is to organize
3-D structural data of large biological molecules
including proteins and nucleic acids of all the
organisms including bacteria,yeast, plants, flies,
other animals and humans.
The three-dimensional structures of the
biological macromolecules data available with
PDB is determined by experimental methods
such as X-ray crystallography, Nuclear magnetic
resonance (NMR) spectroscopy, electron
microscopy.

9. • https://www.rcsb.org/pdb/results/results.do?
tabtoshow=Current&qrid=17DFDDEB