DAS workshop. 10th March 2009

1. A karyotype DAS client
DAS workshop 2009
10th
March
Rafael Jimenez

2. Visualization of genome data in combination with
experimental data and genome analysis helps to
formulate testable hypothesis.
Eukaryotic Genome browsers specialized to represent
annotations on ...

Specific chromosomes

Genome regions in one chromosome

Detailed views on genome regions
Eukaryotic genome analysis requires visualization in a
higher representation level ...
Full genomic context -> Karyotype
Introduction

3. Karyotype DAS client
DAS web browser to visualize Eukaryotic genome data at
the level of karyotype, chromosome and cytoband. Still a
prototype!
For more detail views in a lower representation level it
interacts with the Ensembl web browser.
Karyotype Chromosome Genome region Detailed view
Karyotype DAS viewer Ensembl

4. Implementation
Service
broker
Service
consumer
Service
provider
Service
Contract
...
...
Interact
PublishFind
Service Oriented Architecture

5. Registry
Client Sources
DAS
...
...
...
PublishFind
Distributed Annotation System
Implementation
Interact
DAS
Registry
Genome
Analysis
Karyotype
DAS Client
Cromosome
TypeEnsembl
Gene Expression
Profile Analysis Suite
GPAS
Provide

6. 1

7. 1
Karyotype
Chromosome
Genome region Qualitative
Quantitative (score)
+/-
sources
by view

8. 2 3

9. 2.1

10. 2.2

11. 2.3

12. 2.4

13. 2.5

14. 3.1binning:maxbins

15. 3.2

16. 3.3

17. 4

18. Thank you!
Thanks for its support to …
Thanks to our collaborators …
UCT
South Africa
CBIO, UCT
South Africa
… especially for his contribution on this project to …
Joaquin Tarraga
QuickTime™ and a
decompressor
are needed to see this picture.
Bioinfomatics department