Transcriptome Analysis Console (TAC) Software

1. Transcriptome Analysis Console (TAC) Software
Powerful and intuitive software for deciphering the complexity of the transcriptome
Data to insight in minutes
Detailed analysis is now at the fingertips of every researcher.
Transcriptome Analysis Console (TAC) Software from Affymetrix
takes differential expression profiles to a new level with the ability
to develop meaningful insights from the visualization of miRNA
regulatory networks and biological pathways.
Researchers now have a cost-free solution to quickly analyze
their data, enabling discovery and understanding of the
biological diversity underpinning their research. These tools were
designed with the end user in mind and enable investigators to
analyze and explore data at their own pace. Combined with the
comprehensive coverage of high-density microarray solutions and
Expression Console™
Software from Affymetrix, TAC Software
provides an easy-to-use, integrated solution to go from raw data
to biological results in just a few clicks.
Designed for the biologist
n Perform statistical tests for differential expression.
n Generate lists of differentially expressed genes.
n Explore interactions between coding and non-coding RNA.
n Simplify the interpretation of complex alternative splicing events.
n Easily focus on genes or pathways of interest.
n Link to publicly available annotations.
n Obtain sequence information to design validation experiments.
You decide — gene-level, exon-level, or alternative
splicing analysis
TAC Software supports three types of differential expression analysis
for microarrays from Affymetrix, depending upon array type:
Data workflow
Import expression array
CEL files
Expression
Console
™
Software
Transcriptome
Analysis
Console
(TAC)
Software
1. Select analysis
2. Create conditions
3. Import data
4. Run analysis
Exon
Visualize expression changes
in pathways
Perform gene- or exon-
level normalization and
signal summarization
Visualize results
Gene
Alt.
splice
Link out to public databases
such as Ensembl or NCBI
Visualize mRNA
and miRNA
interactions
DataSheet
Array type
Analysis type
Gene Exon Alt. splicing
Transcriptome view X X
Exon ST X X
Gene ST X X
3' IVT X
miRNA X

2. Map expression changes between miRNA and target genes
Decipher the diverse network of interactions between miRNA and
long coding and non-coding transcripts.
Gene expression changes in pathways
Identify more differentially expressed genes relevant to your
research with pathway visualizations.
Download TAC Software today
To access TAC Software and a complete list of supported arrays,
please visit www.affymetrix.com.
System requirements
Microsoft Windows®
7 professional (SP1)
Microsoft Windows®
10 professional
Operating system (bits) 64-bit
Processor 2.83 GHz Intel®
Pentium®
Quad Core
Memory (RAM)
8 GB (minimum)
16 GB (recommended)
Web browser Internet Explorer®
8.0 and above
Powerful visualization tools
TAC Software provides powerful visualization tools that allow
easy interpretation of significant expression changes. Some of
the visualization tools in TAC include
Scatter plot
Visualize significant
changes in signal
between conditions. Volcano plot
Visualize significant fold
changes between conditions.
Hierarchical clustering
Arrange samples and genes
into groups based on their
expression levels.
Chromosome view
Visualize significant fold
changes along each
chromosome (human only).
Alternative splicing
Utilize intuitive visualizations of alternatively spliced
exons to identify transcript isoforms.
www.affymetrix.com Please visit our website for international distributor contact information.
For Research Use Only. Not for use in diagnostic procedures.
P/N EXP01936 Rev. 9
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