This presentation contains about description of Deodorants and antiperspirants with their Action, Evaluation, Difference between Deodorants and antiperspirants.

1. DEODORANTS AND
ANTIPERSPIRANTS
PREPARED BY:-
PRANJAL SAXENA
B.PHARMA.(8TH SEM.)

2. DEODORANTS AND ANTIPERSPIRANTS:-
• A Deodorants is a product applied to the
body to prevent bad odor caused by the
bacterial breakdown of perspiration in
armpits, feet, and other areas of the body and
do not reduce wetness.
• Antiperspirant affects the odor as well as
prevent seating by affecting sweat glands.

3. PROPERTIES OF DEODORANTS AND
ANTIPERSPIRANTS
• It should not be irritant to skin
• It should not be deteriorate clothing
• It should be safe and non toxic
• Easy to use and adhere well on skin
• Mask odor with perfume
• Absorb perspiration or inhibit the activity of gram positive bacteria, which
cause bad odors..

4. ACTION OF DEODORANTS
• Infection is caused by anaerobic
bacteria often produce strong odor due
the production of short chain fatty
acids, sulfur compounds, ammonia and
polyamines.
• Microorganism and oxidative action
on dead tissue and bacterial products,
eliminate the fetid odor produced by
necrosis.

5. DEODORANTS INGREDIENTS
• ANTI BACTERIAL ACTION:-
• BENZETHONIUM CHLORIDE
• CHLOROHEXIDINE ACETATE
• TRICHLORO HYDROXY
DIPHENYL ETHER
• FORMULATION FORMS:-
• Aerosols
• Sticks
• Creams
• Roll On
• Soaps

6. EVALUATION OF DEODORANTS
• Both in vivo and vitro methods are available
• But in vitro techniques do not provide a reliable indicator of clinical
effectiveness
• The two principal of deodorants efficacy are:-
1.Determination of the effect of treatment of the skin microflora
2.Olfactory assessment of the effect on skin odors
• In this method, olfactory assessment of the effect of deodorants on body may
be performed by direct armpit sniffing

7. ACTION OF ANTIPERSPIRANTS
• Active ingredient will diffuse into the sweat and
apocrine glands and insoluble hydroxide gel
will be produced in sweat pores and thus
physically blocking the release of secretory
products by constricting the opening of the
sweat glands ducts.

8. EVALUATION OF ANTIPERSPIRANTS
• Antiperspirants aim to bring about a temporary
decrease in sweat production in an axillae.
• The most widely used procedure for efficacy
testing of antiperspirants in a gravimetric method
which involves the collection and weighing of
axillary sweat under controlled condition.

9. INGREDIENTS
The FDA publishes an OTC drug monograph that lists which ingredients are approved for
use
The ingredients on the list are limited to:-
Natural antimicrobial agents: aluminum chlorhydrate, aluminum dichlorhydrate
• Aluminum chloride
• Aluminum zinchromium complexes
Of these compounds, the most commonly used is aluminum zinconiumtetrachlorohydrex
glycine
• Alcohol is ingredient present in some rolls on, aerosols and gels
• The active ingredients of antiperspirants and deodorants are often dissolved in alcohol
because it dries quickly once applied to the skin and gives an immediate sense of
coolness

10. WHY CHOOSE A DEODORANTS OVER
ANTIPERSPIRANTS
• Deodorants work by neutralizing the smell of swear and by antiseptic
action against bacteria
• Deodorants are preferable because they don’t interfere with sweating, a
cooling process.
• Antiperspirants because of their ability to reduce perspiration and thus
diminish the medium is a factor in the development of axillary odor, can
claim to be deodorants.

11. DIFFERENCE BETWEEN DEODORANTS AND
ANTIPERSPIRANTS

12. THANK YOU