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CHAPTER – V ANTI-TUMOUR
M.NITHYA B.PHARM, LECTURER, ECOP. 1
ANTI-TUMOUR
Definition
● Also called as Anti cancer or Antineoplatic agent.
● These are the drugs used to treatment of tumour.
Examples:
● Vinca
● Podophyllum
Vinca Podaphyllum
CHAPTER – V ANTI-TUMOUR
M.NITHYA B.PHARM, LECTURER, ECOP. 2
Drug name Synonyms Biological Source Family Chemical
Constituents
Uses
Vinca
Indole
Alkaloid
Catharanthus,
Madagascar
periwinkle.
It consists of dried
whole plant of
Catharanthus roseus
Apocynaceae Vincristine
Vinblastine
Ajmalicine
Serpentine
1. Anti-tumour agent
2. Control diabetes
3. Control
nosebleeds,
bleeding gums,
Mouth ulcers.
4. Control high blood
pressure.
CHAPTER – V ANTI-TUMOUR
M.NITHYA B.PHARM, LECTURER, ECOP. 3
Drug name Synonyms Biological Source Family Chemical
Constituents
Uses
Podophyllum
Resins Indian
podophyllum
Himalayan
may apple
It consists of dried
rhizomes and roots of
Podophyllum
hexandrum or
Podophyllum emodi
Berberidaceae Podophyllin
Podophyllotoxin
α- and β-peltatin
Quercetin
Etoposide
1. Cytotoxic
action
2. Anti-tumour
agent
3. Purgative
4. Bitter tonic

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ANTI-TUMOUR

  • 1. CHAPTER – V ANTI-TUMOUR M.NITHYA B.PHARM, LECTURER, ECOP. 1 ANTI-TUMOUR Definition ● Also called as Anti cancer or Antineoplatic agent. ● These are the drugs used to treatment of tumour. Examples: ● Vinca ● Podophyllum Vinca Podaphyllum
  • 2. CHAPTER – V ANTI-TUMOUR M.NITHYA B.PHARM, LECTURER, ECOP. 2 Drug name Synonyms Biological Source Family Chemical Constituents Uses Vinca Indole Alkaloid Catharanthus, Madagascar periwinkle. It consists of dried whole plant of Catharanthus roseus Apocynaceae Vincristine Vinblastine Ajmalicine Serpentine 1. Anti-tumour agent 2. Control diabetes 3. Control nosebleeds, bleeding gums, Mouth ulcers. 4. Control high blood pressure.
  • 3. CHAPTER – V ANTI-TUMOUR M.NITHYA B.PHARM, LECTURER, ECOP. 3 Drug name Synonyms Biological Source Family Chemical Constituents Uses Podophyllum Resins Indian podophyllum Himalayan may apple It consists of dried rhizomes and roots of Podophyllum hexandrum or Podophyllum emodi Berberidaceae Podophyllin Podophyllotoxin α- and β-peltatin Quercetin Etoposide 1. Cytotoxic action 2. Anti-tumour agent 3. Purgative 4. Bitter tonic