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Uploaded byNithya Murugan
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Pharmacognosy - Astringents

Astringents are substances that cause tissue contraction and dry body secretions, with examples including myrobalan, black catechu, and pale catechu. Myrobalan is rich in hydrolysable tannins and is used as a laxative and stomachic, while black catechu serves as an external astringent for skin issues, and pale catechu is utilized mainly in treating diarrhea and in dyeing industries. The document also describes a confirmatory test for pale catechu using a fluorescence reaction.

Healthcare◦
CHAPTER – V ASTRINGENTS M.NITHYA B.PHARM, LECTURER, ECOP. 1 ASTRINGENTS Definition: ● Astringents are a group of substance that cause the contraction of tissues and also dries the body secretions. Examples: 1. Myrobalan 2. Black catechu 3. Pale catechu
CHAPTER – V ASTRINGENTS M.NITHYA B.PHARM, LECTURER, ECOP. 2 Drug name Synonyms Biological Source Family Chemical Constituents Uses Myrobalan Tannins Chebulic Myrobalans, Harde, Haritaki Myrobalan is the mature dried fruits of Terminalia chebula Combretaceae Hydrolysable tannins Chebulinic acid Chebulagic acid D-galloyl glucose Anthraquinone glycosides (sennosides) Astringent Laxative Stomachic Tonic Anthelmintic
CHAPTER – V ASTRINGENTS M.NITHYA B.PHARM, LECTURER, ECOP. 3 Drug name Synonyms Biological Source Family Chemical Constituents Uses Black Catechu Tannins Kattha Cutch It consists of dried aqueous extract prepared from the heartwood of Acacia catechu Leguminosae Acacatechin Quercetin Gum Quercitrin Used as an astringent externally for Boils, skin eruptions, ulcers
CHAPTER – V ASTRINGENTS M.NITHYA B.PHARM, LECTURER, ECOP. 4 Drug name Synonyms Biological Source Family Chemical Constituents Uses Pale Catechu Tannins Gambier It is a dried aqueous extract of the leaves and young shoots of Uncaria gambier Rubiaceae Catechins Catechutannic acid Catechu red Quercetin Gambier fluorescin Used as an astringent in the treatment of diarrhoea. Mainly used in dyeing and tanning industries.
CHAPTER – V ASTRINGENTS M.NITHYA B.PHARM, LECTURER, ECOP. 5 Gambier - fluorescin Test: Confirmatory test for Pale Catechu: ( Test for Tannins) The drug is extracted with alcohol and sodium hydroxide is added to extract, followed by addition of a few drops of light petroleum. The mixture is shaken and kept for sometime. Green fluorescence is observed in light petroleum layer. So presence of pale Catechu.