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NEW SYLLABUS
BSc Nursing
First Semester
Applied Anatomy
Unit : 1
TISSUES
Tissue
Definition of Tissues
Biological tissue is a collection of interconnected
cells that perform a similar function within an
organism.
In other words, it is a group of cells
working together mainly inside an organ.
Classification of Tissues
Human body is composed of
4 basic types of tissue:
•Epithelial tissue
•Connective tissue
•Muscular tissue
•Nervous tissue
Origin of Tissue
A fertilized egg divides to produce 3 primary
germ cell layers. These layers differentiate to
form the tissues of the body.
Epithelial Tissue
Epithelial cells cover or line all body surfaces,
cavities and tubes. So, These are called
covering epithelia.
Epithelial cells form the functional units of
secretory glands. So, These are called
glandular epithelia.
General Characteristic
✔ Closely attached to each other forming a protective
barrier.
✔ Always has one free (apical) surface open to outside
the body or inside (cavity) an internal organ.
✔ Always has one fixed (basal) section attached to
underlying
connective tissue.
General Characteristic
✔ Has no blood vessels but can soak up nutrients from
blood vessels in connective tissue underneath.
✔ Can have lots of nerves in it (innervated).
✔ Very good at regenerating (fixing itself). i.e.
sunburn, skinned knee.
Functions
❑ To protect the tissues that lie beneath it from radiation,
desiccation, toxins, invasion by pathogens, and physical
trauma.
❑ The regulation and exchange of chemicals between the
underlying tissues and a body cavity.
Functions
❑ The secretion of hormones into the blood vascular system,
and/or the secretion of sweat, mucus, enzymes, and other
products that are delivered by ducts glandular epithelium.
❑ To provide sensation.
❑ Absorbs stomach and intestinal lining (gut).
❑ Filters the kidney.
❑ Forms secretary glands.
Classification of Epithelia
According to thickness
✔ “simple” - one cell layer
✔ “stratified” – more than one layer of cells (which
are named according to the shape of the cells in
the apical layer)
According to shape
✔ “squamous” – wider than tall
✔ “cuboidal” – as tall as wide
✔ “columnar” - taller than wide
Simple squamous epithelium
Description: Single layer of flattened
cells with disc-shaped central nuclei
and sparse cytoplasm; the simplest of
the epithelia.
Function: Passive transport of gases and
fluids.
Location:Alveoli of lungs, lining body
cavities (mesothelium), lining blood
vessels (endothelium)
Simple cuboidal epithelia
Description : Single layer of
cubelike cells with large,
spherical central nuclei.
Function : Secretion and
absorption.
Location: Kidney tubules;
ducts and secretory portions of
small glands; ovary surface.
Simple columnar epithelia
Description: Single layer of tall cells
with round to oval nuclei.
Types:
(i)Ciliated columnar epithelia.
(ii)Non-ciliated columnar epithelia.
Functional: Absorption; secretion of
mucus, Enzymes and other
substances.
Location: Digestive tract, gall
bladder etc.
Stratified squamous epithelia
Description:
Multilayered, surface cell are
squamous, basal cells are cuboidal
and divided constantly.
Function: Protection.
Location: Oral
cavity, cervix, anal canal.
Stratified cuboidal epithelia
Description: Generally two
layers of cube-like cells.
Function: Protection.
Location: Large ducts of sweat
glands, mammary glands, and
salivary glands.
Stratified columnar epithelia
Description:
Multilayered, superficial cells
elongated and columnar.
Function: Protection;
secretion.
Location: Rare in the body;
small amount in the male
urethra.
Pseudo stratified columnar epithelia
Description: Single cell layered, all cell attach to the
basement membrane but not all reach the free surface.
Nuclei at varying depth.
Function: Secretion of mucus, propulsion of mucus
by ciliary action.
Location: Lines of trachea.
Transitional epithelia
Description:
Characterized by domelike cells that are neither
squamous nor columnar. The form of the cells
changes.
Function: Stretching and protection.
Location: Bladder and part of urethra.
Connective Tissues
The tissues that connect the different parts of the
body together are called connective tissues.
General characteristic
✔ The intercellular material is maximum where as the cellular
component is minimum.
✔ Unlike the other tissues, (e.g. epithelium, muscle and nerve)
which are formed mainly by cells, the major constituent of
connective tissue is ECM (Extra-cellular matrix).
✔ Possess cells, fibers and ground substances.
Basic Functions
❑Support and binding of other tissues
❑Holding body fluids
❑Defending the body against infection
❑ macrophages, plasma cells, mast cells, WBCs
❑Storing nutrients as fat
Classification of connective
tissues
Connective tissue proper
Loose connective tissue
Areolar
Description: Gel like matrix with all three fiber types ; cells:
fibroblasts, macrophages, mast cells, and white blood cells.
Function: Its macrophages phagocytize bacteria ; plays
important role in inflammation ; holds and conveys tissue fluid.
Location: Distributed under
of body; surrounds
capillarie:
Loose Connective tissue
Adipose
Description: Matrix as in areolar,
but very sparse; closely packed
adipocytes, or fat cells , have
nucleus pushed to the side by
large fat droplet.
Function: Provides reverse food
fuel; insulates against heat loss;
supports and protects organs.
Location: Under skin; around
kidneys and eyeballs; within
abdomen; in breasts.
Fat
droplets
Nucleus
Loose connective tissue
Reticular
Description: Network of reticular
fibers in a typical loose ground
substance; reticular cells lie on the
network.
Function: Fibers form a soft internal
skeleton that supports other cell types
including white blood cells, mast
cells, and macrophages.
Location: Lymphoid organs(lymph
nodes, bone marrow, and
macrophages.
Dense Connective tissue
Irregular
Description: Primarily
irregularly arranged collagen
fibers; some elastic fibers;
major cell type is the
fibroblast.
Function: Elasticity and
structural
support.
Location: Dermis of the skin;
submucosa of digestive tract and
joints.
Collagen
fibers
Dense Connective tissue
Regular
Description: Primarily parallel
collagen fibers; a few elastin
fibers; major cell type is the
fibroblast.
Function: Attaches muscles to
bones and bones to bones.
Location: Tendons and in most
ligaments.
Cartilage: Hyaline
Description: Amorphous but firm
matrix; chondroblasts produce the
matrix and when mature lie in
lacunae.
Function: Support and reinforces;
to resist compressive stress.
Location: Forms most of the
embryonic skeleton; ends of long
bones; cartilages of nose.
Cartilage: Elastic
Description: Similar to hyaline
cartilage, but more elastic fibers
in matrix.
Function: Maintains the shape
and allows flexibility.
Location: Supports the external
ear(pinna).
Cartilage : Fibrocartilage
Description : Collagen
fibers are predominant ;
matrix is as hyaline but less
firm.
Function: High tensile
strength, absorb
compressive shock.
Location: Intervertebral
disc; discs of knee joint.
Bone
Description: Hard, calcified
matrix containing many collagen
fibers. Very well vascularized.
Function: Bone supports and
protects; provides levers for the
muscles to act on; stores calcium
and other minerals and fat; bone
marrow is the site of blood cell
formation.
Location: Skeleton.
Blood
Description: Liquid connective
tissue, red and white blood cells in
fluid matrix.
Function: Transport respiratory
gases, nutrients, wastes and other
substances.
Location: In the blood vessels.
Muscle Tissue
🞇 Muscle is one of our 4 tissue types and muscle
tissue combined with nerves, blood vessels, and
various connective tissues.
Muscles are quite complex and as we’ll find out,
they are a marvel of both biology and physics.
General characteristics
1. Excitability
• The ability to receive and respond to a stimulus
• In skeletal muscle, the stimulus is a
neurotransmitter
(chemical signal) release by a neuron (nerve cell).
• In smooth muscle, the stimulus
could be a neurotransmitter, a hormone,
stretch, ΔpH, ΔPco2, or
ΔPo2.
• In cardiac muscle, the stimulus
could be a neurotransmitter, a hormone,
or stretch.
• The response is the generation of an electrical
impulse that travels along the plasma membrane of
the muscle cell.
2. Contractility
The ability to shorten forcibly when adequately
stimulated.
This is the defining property of muscle tissue.
3. Extensibility
The ability to be stretched (Extended)
4. Elasticity
The ability to recoil and resume original length
after being stretched.
Functions
• Movement
• Locomotion
• Maintains posture
• Produces heat
• Facial expressions
• Pumps blood
• Peristalsis
3 Types of Muscle Tissue
Skeletal Muscle
Tissue
Description: Long striated
cells with multiple nuclei.
Function: Contraction
for voluntary
movements.
Location: In skeletal muscle.
Smooth Muscle Tissue
Description: Long, spindle-
shaped cells, each with a single
nucleus.
Function: Propulsion of
substances along internal
passageways.
Location: In hollow organs(e.g.
stomach)
Cardiac Muscle tissue
Description: Branching,
striated cells fused at plasma
membranes.
Function: Pumping of
blood in the circulatory
system.
Location: Wall of heart.
Nerve Tissue
By far the most complex tissue in the human
body is nerve tissue.
Formed by a network of more than 100 million
nerve cells, assisted by many more glial cells.
Each neuron has, on an average , at least a
thousand interconnection with other neurons
forming a very complex nervous system.
Functions
 Regulates & controls body functions
 Generates & transmits nerve impulses
 Supports, insulates and protects impulse
generating neurons.
Composition of Nerve Tissue
The nerve tissue is composed of two
elements:
1. The nerve cell or neuron
1. The neuroglia
Neuron
Description: Neurons are
branching cells; cell processes
that may be quite long extend
from the nucleus-containing cell
body.
Function: Transmit electrical
signals from sensory receptors
and to effectors(muscles and
glands) that control their
activity.
Location: Brain, spinal cord and
nerves.
Glial cells
Glia carry nutrients, speed
repair, provide myelin for
axons, support the blood-
brain barrier, and may form
their own communication
network. They are also
involved in neurogenesis.
.
48

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1Tissues .pptx

  • 1. NEW SYLLABUS BSc Nursing First Semester Applied Anatomy Unit : 1 TISSUES
  • 3. Definition of Tissues Biological tissue is a collection of interconnected cells that perform a similar function within an organism. In other words, it is a group of cells working together mainly inside an organ.
  • 4. Classification of Tissues Human body is composed of 4 basic types of tissue: •Epithelial tissue •Connective tissue •Muscular tissue •Nervous tissue
  • 5. Origin of Tissue A fertilized egg divides to produce 3 primary germ cell layers. These layers differentiate to form the tissues of the body.
  • 6. Epithelial Tissue Epithelial cells cover or line all body surfaces, cavities and tubes. So, These are called covering epithelia. Epithelial cells form the functional units of secretory glands. So, These are called glandular epithelia.
  • 7. General Characteristic ✔ Closely attached to each other forming a protective barrier. ✔ Always has one free (apical) surface open to outside the body or inside (cavity) an internal organ. ✔ Always has one fixed (basal) section attached to underlying connective tissue.
  • 8. General Characteristic ✔ Has no blood vessels but can soak up nutrients from blood vessels in connective tissue underneath. ✔ Can have lots of nerves in it (innervated). ✔ Very good at regenerating (fixing itself). i.e. sunburn, skinned knee.
  • 9. Functions ❑ To protect the tissues that lie beneath it from radiation, desiccation, toxins, invasion by pathogens, and physical trauma. ❑ The regulation and exchange of chemicals between the underlying tissues and a body cavity.
  • 10. Functions ❑ The secretion of hormones into the blood vascular system, and/or the secretion of sweat, mucus, enzymes, and other products that are delivered by ducts glandular epithelium. ❑ To provide sensation. ❑ Absorbs stomach and intestinal lining (gut). ❑ Filters the kidney. ❑ Forms secretary glands.
  • 11. Classification of Epithelia According to thickness ✔ “simple” - one cell layer ✔ “stratified” – more than one layer of cells (which are named according to the shape of the cells in the apical layer) According to shape ✔ “squamous” – wider than tall ✔ “cuboidal” – as tall as wide ✔ “columnar” - taller than wide
  • 12.
  • 13. Simple squamous epithelium Description: Single layer of flattened cells with disc-shaped central nuclei and sparse cytoplasm; the simplest of the epithelia. Function: Passive transport of gases and fluids. Location:Alveoli of lungs, lining body cavities (mesothelium), lining blood vessels (endothelium)
  • 14. Simple cuboidal epithelia Description : Single layer of cubelike cells with large, spherical central nuclei. Function : Secretion and absorption. Location: Kidney tubules; ducts and secretory portions of small glands; ovary surface.
  • 15. Simple columnar epithelia Description: Single layer of tall cells with round to oval nuclei. Types: (i)Ciliated columnar epithelia. (ii)Non-ciliated columnar epithelia. Functional: Absorption; secretion of mucus, Enzymes and other substances. Location: Digestive tract, gall bladder etc.
  • 16. Stratified squamous epithelia Description: Multilayered, surface cell are squamous, basal cells are cuboidal and divided constantly. Function: Protection. Location: Oral cavity, cervix, anal canal.
  • 17. Stratified cuboidal epithelia Description: Generally two layers of cube-like cells. Function: Protection. Location: Large ducts of sweat glands, mammary glands, and salivary glands.
  • 18. Stratified columnar epithelia Description: Multilayered, superficial cells elongated and columnar. Function: Protection; secretion. Location: Rare in the body; small amount in the male urethra.
  • 19. Pseudo stratified columnar epithelia Description: Single cell layered, all cell attach to the basement membrane but not all reach the free surface. Nuclei at varying depth. Function: Secretion of mucus, propulsion of mucus by ciliary action. Location: Lines of trachea.
  • 20. Transitional epithelia Description: Characterized by domelike cells that are neither squamous nor columnar. The form of the cells changes. Function: Stretching and protection. Location: Bladder and part of urethra.
  • 21. Connective Tissues The tissues that connect the different parts of the body together are called connective tissues.
  • 22. General characteristic ✔ The intercellular material is maximum where as the cellular component is minimum. ✔ Unlike the other tissues, (e.g. epithelium, muscle and nerve) which are formed mainly by cells, the major constituent of connective tissue is ECM (Extra-cellular matrix). ✔ Possess cells, fibers and ground substances.
  • 23. Basic Functions ❑Support and binding of other tissues ❑Holding body fluids ❑Defending the body against infection ❑ macrophages, plasma cells, mast cells, WBCs ❑Storing nutrients as fat
  • 25. Connective tissue proper Loose connective tissue Areolar Description: Gel like matrix with all three fiber types ; cells: fibroblasts, macrophages, mast cells, and white blood cells. Function: Its macrophages phagocytize bacteria ; plays important role in inflammation ; holds and conveys tissue fluid. Location: Distributed under of body; surrounds capillarie:
  • 26. Loose Connective tissue Adipose Description: Matrix as in areolar, but very sparse; closely packed adipocytes, or fat cells , have nucleus pushed to the side by large fat droplet. Function: Provides reverse food fuel; insulates against heat loss; supports and protects organs. Location: Under skin; around kidneys and eyeballs; within abdomen; in breasts. Fat droplets Nucleus
  • 27. Loose connective tissue Reticular Description: Network of reticular fibers in a typical loose ground substance; reticular cells lie on the network. Function: Fibers form a soft internal skeleton that supports other cell types including white blood cells, mast cells, and macrophages. Location: Lymphoid organs(lymph nodes, bone marrow, and macrophages.
  • 28. Dense Connective tissue Irregular Description: Primarily irregularly arranged collagen fibers; some elastic fibers; major cell type is the fibroblast. Function: Elasticity and structural support. Location: Dermis of the skin; submucosa of digestive tract and joints. Collagen fibers
  • 29. Dense Connective tissue Regular Description: Primarily parallel collagen fibers; a few elastin fibers; major cell type is the fibroblast. Function: Attaches muscles to bones and bones to bones. Location: Tendons and in most ligaments.
  • 30. Cartilage: Hyaline Description: Amorphous but firm matrix; chondroblasts produce the matrix and when mature lie in lacunae. Function: Support and reinforces; to resist compressive stress. Location: Forms most of the embryonic skeleton; ends of long bones; cartilages of nose.
  • 31. Cartilage: Elastic Description: Similar to hyaline cartilage, but more elastic fibers in matrix. Function: Maintains the shape and allows flexibility. Location: Supports the external ear(pinna).
  • 32. Cartilage : Fibrocartilage Description : Collagen fibers are predominant ; matrix is as hyaline but less firm. Function: High tensile strength, absorb compressive shock. Location: Intervertebral disc; discs of knee joint.
  • 33. Bone Description: Hard, calcified matrix containing many collagen fibers. Very well vascularized. Function: Bone supports and protects; provides levers for the muscles to act on; stores calcium and other minerals and fat; bone marrow is the site of blood cell formation. Location: Skeleton.
  • 34. Blood Description: Liquid connective tissue, red and white blood cells in fluid matrix. Function: Transport respiratory gases, nutrients, wastes and other substances. Location: In the blood vessels.
  • 35. Muscle Tissue 🞇 Muscle is one of our 4 tissue types and muscle tissue combined with nerves, blood vessels, and various connective tissues. Muscles are quite complex and as we’ll find out, they are a marvel of both biology and physics.
  • 36. General characteristics 1. Excitability • The ability to receive and respond to a stimulus • In skeletal muscle, the stimulus is a neurotransmitter (chemical signal) release by a neuron (nerve cell). • In smooth muscle, the stimulus could be a neurotransmitter, a hormone, stretch, ΔpH, ΔPco2, or ΔPo2. • In cardiac muscle, the stimulus could be a neurotransmitter, a hormone, or stretch. • The response is the generation of an electrical impulse that travels along the plasma membrane of the muscle cell.
  • 37. 2. Contractility The ability to shorten forcibly when adequately stimulated. This is the defining property of muscle tissue. 3. Extensibility The ability to be stretched (Extended) 4. Elasticity The ability to recoil and resume original length after being stretched.
  • 38. Functions • Movement • Locomotion • Maintains posture • Produces heat • Facial expressions • Pumps blood • Peristalsis
  • 39. 3 Types of Muscle Tissue
  • 40. Skeletal Muscle Tissue Description: Long striated cells with multiple nuclei. Function: Contraction for voluntary movements. Location: In skeletal muscle.
  • 41. Smooth Muscle Tissue Description: Long, spindle- shaped cells, each with a single nucleus. Function: Propulsion of substances along internal passageways. Location: In hollow organs(e.g. stomach)
  • 42. Cardiac Muscle tissue Description: Branching, striated cells fused at plasma membranes. Function: Pumping of blood in the circulatory system. Location: Wall of heart.
  • 43. Nerve Tissue By far the most complex tissue in the human body is nerve tissue. Formed by a network of more than 100 million nerve cells, assisted by many more glial cells. Each neuron has, on an average , at least a thousand interconnection with other neurons forming a very complex nervous system.
  • 44. Functions  Regulates & controls body functions  Generates & transmits nerve impulses  Supports, insulates and protects impulse generating neurons.
  • 45. Composition of Nerve Tissue The nerve tissue is composed of two elements: 1. The nerve cell or neuron 1. The neuroglia
  • 46. Neuron Description: Neurons are branching cells; cell processes that may be quite long extend from the nucleus-containing cell body. Function: Transmit electrical signals from sensory receptors and to effectors(muscles and glands) that control their activity. Location: Brain, spinal cord and nerves.
  • 47. Glial cells Glia carry nutrients, speed repair, provide myelin for axons, support the blood- brain barrier, and may form their own communication network. They are also involved in neurogenesis.
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