Punnett squares are used to predict the possible combinations of dominant and recessive genes that will be passed on from parents to offspring. The dominant genes from the father are written along the top of the square and the mother's recessive genes are written along the side. Each box represents a possible genetic combination, with the dominant genes always being placed first and the recessive genes last in each box. The percentage of each combination can be determined by the number of boxes showing that combination, with each box representing 25% of the total offspring.