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Vasospastic angina

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Rickettsia Rickettsii
Rickettsia Rickettsii

Vasospastic angina

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Vasospastic angina Pathogenesis • Hyperreactivity of coronary smooth muscle Clinical presentation • Young patients (age <50) • Smoking (minimal other CAD risk factors) • Recurrent chest discomfort • Occurs at rest or during sleep • Spontaneous resolution <15 minutes Diagnosis • Ambulatory ECG: ST elevation • Coronary angiography: No CAD Treatment • Calcium channel blocker (preventive) • Sublingual nitroglycerin (abortive)

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Vasospastic angina

  • 1. Vasospastic angina Pathogenesis • Hyperreactivity of coronary smooth muscle Clinical presentation • Young patients (age <50) • Smoking (minimal other CAD risk factors) • Recurrent chest discomfort • Occurs at rest or during sleep • Spontaneous resolution <15 minutes Diagnosis • Ambulatory ECG: ST elevation • Coronary angiography: No CAD Treatment • Calcium channel blocker (preventive) • Sublingual nitroglycerin (abortive)