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Feeding, Fueling and Healing the World
- 1. Click to edit Master text styles June 2015 Feeding, fueling and healing the world
- 2. ncbiotech.org 11 million pounds of food are eaten every minute. 2ncbiotech.org
- 3. 11 million pounds of food are eaten every minute. 275,000 babies are born every day. 3ncbiotech.org CREDIT:istockphoto.com
- 4. 4ncbiotech.org 11 million pounds of food are eaten every minute. 275,000 babies are born every day. 14.1 million people are diagnosed with cancer every year. CREDIT:shutterstock.com 4ncbiotech.org
- 5. 5ncbiotech.org Population growth, food demand, and the spread of disease challenge the world’s resources. CREDIT:istockphoto.com
- 6. How do we continue to feed, fuel and heal the global population? 6 CREDIT:istockphoto.com ncbiotech.org
- 8. Biotechnology uses living systems and organisms to solve problems and create transformational products. 8 Vaccines that prevent disease. Spider silk vests that protect battlefield soldiers. Crops that thrive in drought. ncbiotech.org
- 10. CREDIT:Sartorius The world of biotechnology is complex and counterintuitive. 10ncbiotech.org
- 11. 11ncbiotech.org Long timelineFunding Workforce Protection Grants High Cost Jobs Regulatory Framework 10-15 years Risk Profile 11ncbiotech.org
- 13. 13ncbiotech.org Ways We Serve North Carolina
- 14. We work to eliminate funding gaps. We know the critical points where our funding will have the greatest impact. And more often than not, we provide funding when no one else will. 14ncbiotech.org
- 15. Success Story: Entegrion 15 Entegrion’s wound treatment technology can save lives on the battlefield. They needed funding to prove their idea. CHALLENGE ncbiotech.org
- 16. Success Story: Entegrion The Biotech Center awarded Entegrion a $150,000 Small Business Research Loan in 2003 and $284,000 in three Collaborative Funding Grants over a four year period. NCBIOTECH’S ROLE 16ncbiotech.org
- 17. Success Story: Entegrion 17 $88M in contracts from various units in the U.S. Department of Defense and more lives saved. IMPACT CREDIT:Entegrion ncbiotech.org
- 18. We connect industry, academia, and government resources to get things done. We grew with the life science sector in North Carolina. When a new idea emerges, we help facilitate the partnerships needed for it to succeed. Our many events keep the industry energized. 18ncbiotech.org
- 19. Success Story: Mid-Atlantic Feed Grain Coalition North Carolina’s $68B animal meat industry imported about two-thirds of its feed. The costs of importing were increasing expenses, threatening business. CHALLENGE 19ncbiotech.org
- 20. Success Story: Mid-Atlantic Feed Grain Coalition The Ag Biotech Initiative connected a coalition of university researchers. Scientists identified sorghum, a cereal grain that resembles corn, as a feed replacement option. NCBIOTECH’S ROLE 20ncbiotech.org
- 21. Success Story: Mid-Atlantic Feed Grain Coalition Sorghum production increased 5X in North Carolina, saving millions for the animal meat industry. IMPACT 21ncbiotech.org CREDIT:istockphoto.com
- 22. Together, ideas, funding, and connections create jobs We train the best workforce, students, and educators to build strong companies and power our thriving ecosystem. We understand a technology’s potential value and communicate it to the stakeholders who matter. This means our leading companies stay here, at home, in our state. 22ncbiotech.org
- 23. 23 Duke University spinout Argos Therapeutics has a product that can treat many cancers. Argos needed a place to manufacture the clinical trial doses. But it was unable to find financing for the facility. Success Story: Argos CHALLENGE ncbiotech.org
- 24. 24 Success Story: Argos The Bioscience Industrial Development team helped Argos communicate the need to state and local officials, helping Argos secure financing. NCBIOTECH’S ROLE ncbiotech.org
- 25. 25 CREDIT:Argos Success Story: Argos Argos’ new $57M facility is under construction in Durham and will provide 230 future jobs. IMPACT ncbiotech.org
- 26. Ways We Serve North Carolina 26ncbiotech.org Recruitment Business Growth Workforce Partnerships Networking Licensing Coaching Events Loans Grants Infrastructure Investors
- 27. “ This [funding] was crucial for our development and it is why we were able to equip and staff a commercial diagnostic laboratory in RTP. John Bilello, CEO | Ridge Diagnostics 27 In Our Partners’ Words ncbiotech.org
- 29. ncbiotech.org North Carolina’s Biotechnology Industry 29ncbiotech.org
- 30. ncbiotech.org The State’s Knowledge Infrastructure 30ncbiotech.org
- 31. ncbiotech.org The State’s Workforce Infrastructure 31ncbiotech.org 31
- 32. ncbiotech.org North Carolina is one of the most competitive and fastest growing biotechnology clusters. Life science jobs grew at four times the national rate from 2000 to 2012 30.9 7.4 1 N.C. life science U.S. life science N.C. private sector *Numbers are in percentages 32ncbiotech.org
- 33. Ways We Serve North Carolina 33ncbiotech.org
- 34. Let’s feed, fuel and heal the global population 3434 CREDIT:Syngenta ncbiotech.org
- 35. We are committed to North Carolina leading the way. 3535ncbiotech.org
Editor's Notes
- Thank you for inviting me to speak today. In order to tell you about the North Carolina Biotechnology Center, I want to step back and tell you a story. It has a strong time element to it, so take note of that as we move through these slides.
- Around the world, 11 million pounds of food are eaten every minute
- Each day, 275,000 babies are born.
- And over the course of a year, 14.1 million people will be diagnosed with cancer
- These are significant challenges created by a growing population. And they create a consistent pressure on our finite resources. Which gives us a big question
- How do we feed, fuel and heal the global population? I have a simple answer
- Many of these challenges can be solved with the tools of biotechnology.
- So what is biotechnology, this great problem solver? It’s based on living systems. It takes those systems and puts them to work to solve a problem or to create a product. At NCBiotech, we think of biotechnology as a toolbox. There are a number of things that living systems or organisms do naturally. The toolbox harnesses those activities to create products and solve problems. For example: Many of us are familiar with vaccines – we get our flu shots every year. But did you know that spider silk can be woven into a material that’s stronger than Kevlar. It makes a lightweight vest that can protect soldiers on the battlefield. Making enough spider silk? That’s biotech. Right here in North Carolina, crop biotech companies are testing crop varieties that need less water to grow. That means more farmers around the world will be able to feed their families and communities. Those are just three applications of biotechnology that help heal fuel and feed our growing population.
- Biotechnology has specific solutions to our challenges to heal, fuel and feed. The process of getting these solutions to market creates high-paying jobs and wealth, and works to develop our communities. Where these two overlap is an opportunity. We can feed the world and create jobs. This sounds great, right?
- Well. It turns out our simple answer is not an easy answer. How so?
- Here are three ways biotechnology solutions come to be. Along the way, they encounter many hurdles. These obstacles are unique to the life science, and the regulation in the industry creates a unique risk profile with a long, expensive time to market.
- This is where the Biotech Center comes in. Here are the same three needs. But now, a team of experts – in science, business, finance, training and more – come in and organize the clutter. These experts, the Biotech Center staff, connect each university technology or company need to resources required to move forward. The result, is technology moves to marked faster, and we heal, fuel and feed the world. Faster, and with products from North Carolina.
- Let’s look at this hub more closely. First ideas need some funding to move forward. That’s not a new concept, but the way the Biotech Center funds is new. Second, we connect resources. This is the single biggest way we can really catalyze growth. Third, we create jobs by helping company grow in North Carolina or move here. This is traditional economic development, but again with specialized expertise applied.
- NCBiotech has several programs – grants and loans – that fund ideas. Our funding is targeted at funding gaps. For example, a technology may need more proof-of-concept data before it’s a good candidate to be licensed. We target our funding where it can prove a case and leverage additional investment in an idea. Projects funded by our grant programs, on average, bring in $28 more for each $1 in grants. And our loan portfolio companies attract $118 in investment for each $1 loaned. These are great results, ones we all hope for in our own investments. But how does it work?
- One example starts on the battlefield, where soldiers get wounded. The immediate threat following the injury is blood loss. What if there was a bandage that soldiers could carry that actually helped stop the bleeding. It’s like an emergency tourniquet, but actually includes a medicine that works to clot the blood. Researchers at ECU and UNC had such a technology, but they had a lot to prove before it could be used on the battlefield, or in other trauma cases.
- We also provided $284,000 in three NCBiotech Collaborative Funding Grants subsequently that went to scientists working on Entegrion technologies at UNC and ECU in 2005, 2006 and 2009. This helped develop what would become a commercially and medically significant product bloodline. Their wound dressing that helps stop bleeding is being used today. And its technology to freeze-dry platelets, which normally have a short life, is progressing through the testing phases. And …
- …attracted funding from the Department of Defense. $88 million in funding, so far. And today we have a bandage, and it’s helping to save lives. We’re saving lives not just because of the Biotech Center’s funding, but we did help get it to market faster, and our funding does make sure these solutions of the future come from North Carolina. This is one example of how NCBiotech works to heal the world.
- Some people think that funding is the most important part. Now, don’t get me wrong, money is critical to a technology’s success, particularly in the life sciences. But NCBiotech’s sweet spot is connecting the many people who work in the industry to the information that they need to get their jobs done faster. This might be: Helping people come together to share ideas on a scientific topic, like plant molecular biology. Providing a facility for meetings Consulting with principal investigators on a grant to improve a funding application Connecting entrepreneurs with the resources needed to launch a company. This could be one meeting. Or it could be a larger initiative, like a coalition put together by our Ag Biotech Initiative.
- North Carolina’s meat animal industry is worth about $6B to North Carolina. It imports about two-thirds of its animal feed. A couple of years ago, fuel costs were rising, and with them, the price of animal production. The businesses had to consider whether it would be cheaper to move closer to the source of the food.
- Here again, there had to be a solution to this problem. But companies and universities don’t always speak the same language. So NCBiotech put a group of scientists around the table, and explained the industry’s need. This coalition of researchers from North Carolina, Virginia and South Carolina ran some tests on different alternatives to corn for food. They found sorghum. It has the nutritional profile necessary, and it grows well in North Carolina. Now, farmers decide what to grow, and animal producers decide what to buy.
- But because these groups trusted us, we had a solution that was market ready. And sorghum production was increased five times in 2013. We estimate this saved $30M or more for the industry. For North Carolina, it means that a very significant set of jobs stays here. This is one way that NCBiotech’s efforts feed the world.
- Funding ideas and connecting resources starts to build an ecosystem that helps us move into traditional economic development – creating jobs. New companies like the environment and want to come here Existing companies are able to grow here. Still, these are not typical economic development needs. The regulations are more intense than an automobile manufacturer would face. The permitting and zoning process is more complicated than an equipment vendor must pass. And the supply chain is different from a call center’s.
- To illustrate that, let me tell you another story, about a company named Argos. This company was exactly what we want. A Duke technology became a company. And what were they working on? A vaccine to treat cancer. Again, sounds great. What’s the obstacle? Argos needed to build a facility to produce batches of their product for testing. They needed financing, but had no revenue. That makes it difficult for a bank to invest. Also, Argos was fielding calls from other states and countries, which promised millions of dollars if Argos would move.
- NCBiotech understood what was going on with Argos. We were able to act as a neutral party and explain the technology and the risk to state and to private financers.
- The result is that in the summer of 2014, Argos announced a $57M facility, which creates construction jobs, and 230 permanent jobs as the manufacturing scales up.
- Job creation like that at Argos comes when the right ecosystem is in place. We had to fund ideas and connect resources so that we can create jobs. As you heard from these stories, there are many individual pieces and steps to getting life science technology to market. You heard just three examples today.
- Here’s one more. This is what our support means to one company. These stories are replicated over and over again across the state.
- And this is a statewide industry. We have 600 life science companies in North Carolina, and you can see them stretching from Wilmington to Asheville here. You can imagine that support companies and their jobs touch all 100 counties. That activity makes North Carolina a top-tier location for biotechnology.
- And this is real impact. Those 600 companies employ 61,000 people, Creating 73 billion in economic activity Generating $1.7B in state and local taxes.
- These results come from a strong scientific foundation at our public and private universities.
- And companies come here, and grow here, because of our highly skilled workforce. And if you know a teenager who is scientifically inclined, float the industry average salary in front of them. $81,000 annually.
- It’s a growing industry in North Carolina. 30.9 percent from 2000 to 2012. And I think the impact of a Biotechnology Center is clear on this slide. The yellow bar on the left is North Carolina’s growth. 30.9 percent. The middle bar is the U.S. life science industry, at 7.4 percent growth. So North Carolina’s life science jobs are growing 4X faster than the country’s. We’re doing something right here. This is the impact that …
- Funding ideas, connecting resources and creating jobs has on North Carolina. It’s because North Carolina thought ahead, because we built a strong life science foundation, and because we at the Biotech Center understand the challenges that life science faces. And because we understand that the impact is measured in more than jobs and billions.
- It’s measured in accelerating the technology that will feed, fuel and heal a global population.
- At NCBiotech, our commitment is that North Carolina will lead the way.