This full curriculum vitae has been uploaded for the potential employers offering a job opportunity in the area of synthetic organic and analytical chemistry.

1. CURRICULUM VITAE
1
PERSONAL INFORMATION
Name: Muhammad Shamsul Azim Khan, Ph.D.
Date of birth: 30-12-1975
Nationality: Bangladesh
Current mail address: Podjavorinské 1598/6, Chodov, 149 00 Praha, Czech Republic
[with permanent residency (s trvalým pobytem) in the Czech Republic]
European driving license: Group “B” - active
Email: azim2005@gmail.com
Mobile: + 420-776 837 244 (Czech Republic).
Skype ID: azimchem
Linkedin profile: https://cz.linkedin.com/in/msakhan1975
KEY SKILLS AND ABILITIES / RESEARCH INTERESTS
• experienced in synthetic organic chemistry (10 years, research and development sector)
• custom / multi-step synthesis (from mg to multi-gram scale) of new/old compounds including
macrocyclic receptors (cucurbit[n]urils, cyclodextrin dimer, calix[n]phyrin, porphyrin and
porphyrinoids), heterocycles, biologically active compounds, functionalized carbohydrates etc.
• development of separation and purification method using various chromatographic instruments
(HPLC-MS: preparative/analytical etc.) and characterization of the synthesized compounds using
various spectroscopies (FT-NMR, UV-vis, FT-IR, etc.)
• experienced in qualitative and quantitative measurement of supramolecular binding interactions
between synthetic receptor and other chemical entity such as drug
• independent, dedicated, resourceful, strong analytical ability, innovative
• excellent communication and presentation skills
• research interest includes design and synthesis of active pharmaceutical ingredient (API), fine
chemicals, new drug discovery, medicinal and analytical chemistry etc.
• experienced R & D chemist in the paint and surface coating industry
ACADEMIC QUALIFICATION
1. 09/2006 - 09/2012
Ph.D. degree completed (Field: Macromolecular Chemistry)
Department of Chemistry, Masaryk University in Brno, Czech Republic
2. 2001 - 1999
M.Sc. in Organic Chemistry (Thesis - Organic synthesis)
Department of Chemistry, Jahangirnagar University, Savar - 1342, Dhaka, Bangladesh
Result: 1st class 2nd position (Obtained marks - 71.86 %)
3. 1999 - 1993
B.Sc. (Honors) in Chemistry
Department of Chemistry, Jahangirnagar University, Savar-1342, Dhaka, Bangladesh
Result: 1st class 1st position (Obtained marks - 69.25 %)
4. 1993 - 1991
Higher Secondary Certificate (H.S.C) Exam’1993
Dhaka College, Dhaka, Bangladesh
Result: 1st division (Obtained marks - 69.9 %)
5. 1991 - 1989
Secondary School Certificate (S.S.C) Exam’1991
A.K. Higher Secondary School, Dhaka-1236, Bangladesh
Result: 1st division with star marks (Obtained marks - 77 %)
RESEARCH FELLOWSHIP / ACADEMIC / INDUSTRIAL JOB EXPERIENCE
1. 05/2013 - 06/2015 (2-year, 2-month)
Postdoctoral research fellow (co-financed by EU grant)
University of Chemical Technology Prague, Technická 5, Prague 6, Czech Republic

2. CURRICULUM VITAE
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Project title: Synthesis, purification and characterization of
i) calix[n]phyrin (n=4, 6) conjugates with Tröger’s base (TB) for sensing cations or anions, and
ii) TB-Tris(mannose) cluster
Accomplishments: Multi-step synthesis of Calix[n]phyrin-Tröger’s base (TB) (n= 4, 6) conjugates
was performed with the aim to construct a possible molecular tweezer for sensing cation or anion
(Scheme 1).
Multistep synthesis of a selectively functionalized D (+)-mannose derivative with the aim to construct
a TB-mannose cluster conjugate which is supposed to be water soluble and would interact with
various biological entities like protein, amino acid etc.
2. 01/2015 – 05/2015 (4-month)
Visiting postdoctoral fellow (porphyrin chemistry research group of Prof. L. Latos-Grażyński)
Department of Chemistry, University of Wroclaw, Wroclaw, Poland
Project title: Synthesis, purification and characterization of a carbachlorin molecule (structurally
related to a Chlorin molecule, 20 π electron system) and it’s complexation with transition metal.
Accomplishments: Final carbachlorin was synthesized with optimization and characterized.
3. 08/2011 – 12/2012 (1-year, 5-month)
Research assistant
Institute of Organic Chemistry and Biochemistry (IOCB), Academy of Science of the Czech Republic
(AS CR), Flemingovo nám. 2, 166 10 Praha 6, Czech Republic
Project title: Synthesis, purification and characterization of αβ-cyclodextrin (CD) heteroduplex and
it’s complexation with guest molecules.
β- CD
α- CD α- CD
β- CD
α- CD
β- CD

3. CURRICULUM VITAE
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Accomplishments: αβ-CD heteroduplex was synthesized by oxidative coupling between α-CD dithiol
(6-step synthesis) and β-CD dithiol (6-step synthesis). Selective synthesis of the aforementioned
heteroduplex was also performed in the presence of custom made template. Method of its separation
and purification was developed using chromatography - gradient elution: LC-MS (waters), reverse
phase-preparative/analytical, flash etc.). In water, the duplex showed high binding affinities
(determined by VP-ITC technique) with several probe guests.
4. 09/2006 - 02/2011 (4-year, 5-month)
Ph.D. research student [Doctoral stipend + Dean award (54- month) + Rector award (12-month)]
Department of Chemistry, Masaryk University in Brno, Czech Republic
Dissertation title: Modified cucurbit[n]urils: synthesis and supramolecular interactions.
Accomplishments: My Ph.D. dissertation comprised of four projects: two major independent and two
collaborative projects.
Major projects: Two new water soluble functionalized cucurbit[n]urils (A and B, CB[n], n = 6) were
synthesized, purified and characterized and their supramolecular interactions with organic guests were
studied. Binding modes of the macrocycle B (hexamethylcucurbit[6]uril, MeCB[6]) with viologen
guests (MeV2+
and MeV+
) in solution and solid state were determined. Macrocycle B exhibited strong
binding affinity toward MeV2+
guest (K = 105
M-1
) in pure water. 1
H NMR and UV-vis titration
experiments showed remarkable weakening of the B-MeV2+
complex in the presence of NaCl.
Synthesis of macrocycle A was the first example of substituted CB[6] with one substituent at the
methylene bridge position. New method of synthesis, isolation and purification was developed. The
results introduced a milestone concept in the chemistry of CB[n] compound and further extend its area
of application.
Collaborative projects: In one project, new method of deprotection of a propylene glycoluril dimer
(C) was introduced. In the second project, a CB[6] based supramolecular shuttle (rotaxane) was
constructed based on the complexation studies between CB[6] and a bispyridinium ethylene guest.
5. 11/2005 - 02/2006 (4-month)
Research student
University of Chemical Technology Prague, Technická 5, Prague 6, Czech Republic
Project summary: Synthesis, purification and characterization of binaphthalene based receptors for
binding anions.
6. 10/2004 - 07/2005 (10-month)
Research student [UNESCO - IUPAC Postgraduate course in polymer science (with research)]
Institute of Macromolecular Chemistry, AS CR, Heyrovského nám. 2, Praha 6, Czech Republic
A B

4. CURRICULUM VITAE
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Accomplishments: A series of bisphosphonic acid compounds (I-III, strong chelating agents) having
functional groups: NH2, OH, Br, H2C=C- were synthesized and characterized for surface modification
of magnetic oxide nanoparticles such as magnetite (Fe3O4), and Co-ferrite.
7. 08/2002 - 03/2004
Assistant Chemist (production, quality control, research and development)
Pailac paint and chemical company (Pvt.) Ltd., Dhaka, Bangladesh
8. 05/2002 - 07/2002
Lecturer in Chemistry, College of development alternative (CODA), Dhaka, Bangladesh
9. 1999 – 2001
M.Sc. thesis student
Thesis title: Synthesis of Schiff bases, thiadiazoline derivatives and some heterocyclic compounds as
probes for pharmacological studies especially as Anti-cancer agents.
Accomplishments: A series of aldehyde-Δ2
-1, 3, 4-thiadiazolines (Scheme 1) were synthesized from
oxidative cyclization of the aldehyde thiosemicarbazones in acetic anhydride in hot condition. In
addition, some of the aldehyde thiosemicarbazone underwent cyclization with p-substituted
phenacylbromide to give the phenylthiazolyl hydrazone (Scheme 3). Some of the synthesized
compounds were shown to have cytotoxic and antibacterial activity.
EXPERIENCE IN INSTRUMENTATION
1. Varian/Bruker 300/400/500 MHz FT-NMR (manual/autosampler), 2. UV-vis and FT-IR
spectroscopy, 3. RP preparative chromatography (Biotage - Horizon fraction collector) and flash
chromatography, 4. RP preparative/ analytical LC-MS with fraction collector (Waters), HPLC, Gel
permeation chromatography, Ion exchange chromatography, 5. Theoretical knowledge on MALDI-
TOF MS, 6. VP - ITC (microcal), 7. Autoclave, 8. Potentiometric titrator (Metrohm), 9. Rotary
evaporator, 10. High vacuum - Argon setup for moisture free and inert reaction, 11. Dry solvent setup
under inert atmosphere

5. CURRICULUM VITAE
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COMPUTER LITERACY AND EXPERIENCE ON RESEARCH DATA BASE
MS-Office applications (word, excel, power point), adobe photoshop and illustrator, chemical
structure drawing softwares (Isis draw, ChemBioOffice), data analysis softwares (Origin, PSI-plot),
scanning, computer hardware and trouble shooting, e-mail and internet browsing.
SciFinder Scholar, Reaxys, Reference Manager Software, End note, Chemical abstracts on CD, Web
of Science.
LIST OF PUBLICATIONS (Total citation= 48, according to Google Scholar since 2009)
8. L. Gilberg, M S A. Khan, M. Enderesova, V. Sindelar.
Cucurbiturils substituted on methylene bridge.
Organic Letters, 16 (9), 2446-2449, 2014 (IF 6.142, 2012)
7. V. Kolman, M S A. Khan, M. Babinsky, R. Marek, V. Sindelar.
Supramolecular shuttle based on inclusion complex between cucurbit[6]uril and bispyridinium
ethylene.
Organic Letters, 13 (23), 6148-6151, 2011. (IF 5.862, 2011)
6. M. Stancl, M S A. Khan, V. Sindelar.
1,6-Dibenzylglycoluril for Synthesis of deprotected glycoluril dimer.
Tetrahedron, 67, 8937-8941, 2011. (IF 3.025, 2011)
5. M S A. Khan, D. Heger, M. Necas, V. Sindelar.
Remarkable salt effect on stability of supramolecular complex between modified cucurbit[6]uril and
methylviologen in aqueous media.
Journal of Physical Chemistry B, 113 (32), 11054-11057, 2009. (IF 4.19, 2009)
4. M S A. Khan, V. Sindelar.
Synthesis of modified cucurbit[n]urils.
Chemické listy, 102, 1245-1246, 2008. (IF 0.62, 2010)
3. M S A. Khan, M. Benes.
Functionalized bisphosphonic acids for surface modification of magnetic iron oxide and other metal
oxides.
In book of proceedings, p.27-32. EUROGREENPOL- First European Summer School on Green
Chemistry of Polymers, Iasi, Romania, 21-27 August 2005.
2. M S A. Khan, M. Rabiul Islam, S. Malik, H. Duddeck.
Synthesis of some aldehyde schiff bases of 4-amino-1,2,4-triazine-3-thione and p-substituted
phenylthiazolyl derivatives and their cytotoxic activities.
Journal of the Bangladesh Chemical Society, 17(1), 52-58, 2004.
1. M. Rabiul Islam, M S A. Khan, D. Devnath, M. Mizanur Rahman Khan.
Synthesis of some aldehyde- Δ2-1, 3, 4 -thiadiazoline heterocycles.
Journal of the Bangladesh Chemical Society, 16(2), 124-132, 2003.
CONFERENCE PARTICIPATION (INCLUDING BOOK OF ABSTRACT)
7. 49th Advances in Organic, Bio-organic and Pharmaceutical Chemistry, Liblice2014, 7-9.
November 2014, Lazne Belohrad, Czech Republic
Contribution: Poster (P27)
In book of abstract: Tröger’s Base (TB) Conjugates with Calix[n]phyrins, p. 73.
6. XII International Congress of Young Chemists, ‘YoungChem2014’
8 - 12. October’ 2014, Szczecin, Poland
Contribution: Poster (P37)
In book of abstract: Tröger’s Base (TB) Conjugates with Calix[n]phyrins, p. 109.
5. Modified cucurbit[6]uril and its supramolecular interactions with methylviologen. In Chemické
listy, Book of Abstracts – Progress in organic, bio-organic and pharmaceutical chemistry –
“LIBLICE 2009“. 103, p.961, ISSN 0009-2770, 2009
4. 44. conference on progress in organic, bio-organic and pharmaceutical chemistry, Liblice, 27-29.
November 2009, Czech Republic
Contribution: Oral presentation

6. CURRICULUM VITAE
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3. 10th international conference on calixarenes (ICC) Seoul. (13-16 July 2009) - Department of
Chemistry, Korea University, Seoul, Korea
Contribution: Poster
2. 1st international conference on cucurbiturils (ICCB), Pohang, Korea (July 10-11, 2009) -
Department of Chemistry, Pohang University of Science and Technology
Contribution: Poster
1. 4th meeting on chemistry and life, Brno. (Sept 9-11, 2008) - Faculty of Chemistry, Brno University
of Technology
Contribution: Poster
LANGUAGE SKILLS
English: excellent (2nd language)
Czech : very good (secured velmi dobře, 80%, )
Bengali: mother tongue
Hindi : passive
I hereby declare that all the information stated above is correct.
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