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Extracutaneous atypical syphilis in hiv
1. Extracutaneous atypical syphilis in HIV-infected patients.
Abstract
INTRODUCTION AND OBJETIVE:
We describe a series of cases of syphilis with atypical extracutaneous clinical presentation
diagnosed in HIV-infected patients.
METHODS:
Retrospective observational study. All cases of syphilis diagnosed in HIV-infected patients
during the period between June 2013 and June 2016 in a tertiary hospital of the Barcelona
metropolitan area were analysed.
RESULTS:
A total of 71 cases of syphilis were diagnosed, 32 of them presenting with clinical signs or
symptoms. Seven of these cases (9.8% of the total and 21.8% of the symptomatic cases)
had atypical presentations with extracutaneous involvement: ocular (4), gastric (1),
multiple hepatic abscesses (1) and generalised adenopathies (1). Patients were treated
with intramuscular or intravenous penicillin and the clinical and serological evolution was
good in all of them.
CONCLUSIONS:
Extracutaneous atypical clinical presentations were observed in 21.8% of symptomatic
cases of syphilis in HIV+ patients with ocular involvement being the most freqent.
KEYWORDS:
Hombres que tienen sexo con hombres; Human immunodeficiency virus; Infecciones de
transmisión sexual; Men who have sex with men; Sexually transmitted infections; Syphilis;
Sífilis; Treponema pallidum; Virus de la inmunodeficiencia humana
REFERENCIAS:
Prieto P, Imaz A, Calatayud L, García O, Saumoy M, Podzamczer D.
Med Clin (Barc). 2017 Jul 21. pii: S0025-7753(17)30475-X. doi:
10.1016/j.medcli.2017.06.006. [Epub ahead of print] English, Spanish.
![Extracutaneous atypical syphilis in HIV-infected patients.
Abstract
INTRODUCTION AND OBJETIVE:
We describe a series of cases of syphilis with atypical extracutaneous clinical presentation
diagnosed in HIV-infected patients.
METHODS:
Retrospective observational study. All cases of syphilis diagnosed in HIV-infected patients
during the period between June 2013 and June 2016 in a tertiary hospital of the Barcelona
metropolitan area were analysed.
RESULTS:
A total of 71 cases of syphilis were diagnosed, 32 of them presenting with clinical signs or
symptoms. Seven of these cases (9.8% of the total and 21.8% of the symptomatic cases)
had atypical presentations with extracutaneous involvement: ocular (4), gastric (1),
multiple hepatic abscesses (1) and generalised adenopathies (1). Patients were treated
with intramuscular or intravenous penicillin and the clinical and serological evolution was
good in all of them.
CONCLUSIONS:
Extracutaneous atypical clinical presentations were observed in 21.8% of symptomatic
cases of syphilis in HIV+ patients with ocular involvement being the most freqent.
KEYWORDS:
Hombres que tienen sexo con hombres; Human immunodeficiency virus; Infecciones de
transmisión sexual; Men who have sex with men; Sexually transmitted infections; Syphilis;
Sífilis; Treponema pallidum; Virus de la inmunodeficiencia humana
REFERENCIAS:
Prieto P, Imaz A, Calatayud L, García O, Saumoy M, Podzamczer D.
Med Clin (Barc). 2017 Jul 21. pii: S0025-7753(17)30475-X. doi:
10.1016/j.medcli.2017.06.006. [Epub ahead of print] English, Spanish.](https://image.slidesharecdn.com/extracutaneousatypicalsyphilisinhiv-171004171105/85/Extracutaneous-atypical-syphilis-in-hiv-1-320.jpg)
