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8. Consider the following diagram of a segment of eukaryotic chromosomal DNA. The filled
boxes denote DNA encoding exons, and the hollow boxes denote DNA encoding introns; the
central horizontal line separates the two strands of the double helical DNA. In a series of
cartoons, sketch the events that occur before the fully mature mRNA encoded by this DNA
arrives in the cytoplasm for translation into a protein. Include capping, splicing, poly-
adenylation, and transcription (which do not occur in that order). Explicitly denote which steps
occur in the nucleus and which occur in the cytoplasm.

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