Treatment of an osseous –cyst-like lesion (OCLL) with Quinaquanone (Bonekare)in a young foal.

1. BoneKare™ Case Study
Treatment of an osseous – cyst-like lesion (OCLL) with Quinaquanone® (BoneKare™)in a young foal.
Dr Thorsten Feddern - Bellowhill Veterinary Clinic
History
A 4 week old warmblood filly foal was presented with a severe hindlimb lameness, that had initially been observed by the owner five days previously.
Little swelling of the fetlock joint had been present at that time and this together with the degree of lameness had increased steadily up to the time of
the examination.
Mare and foal had been kept at pasture during the day and stabled at night. No treatment had been administered prior to the examination.
Clinical findings
The foal was in normal bodily condition but somewhat lethargic.
The right hind fetlock joint was severely swollen with only the tip of the toe resting on the ground. In walk the filly did not bear weight.
Palpation revealed a grossly distended joint capsule and substantial diffuse swelling around the joint. Any movement or attempted manipulation
triggered a violent pain response.
Body temperature was within normal limits, no further joint swellings were observed and the umbilical area appeared normal.
Haematological findings
The fibrinogen was raised (4.1g/l). No further abnormalities were found.
Radiographic findings
Radiographs revealed the presence of an osseous cyst-like lesion in the medial condyle of the third metatarsal bone, that measured approximately
10-12mm in diameter.

2. Before Age: 2.5 monthsBefore Age: 2.5 months

3. ...Continued
Treatment
The antibiotic treatment that had been prescribed after the initial examination (Cefquinome 4,5% 1mg/kg) was discontinued after 5 days. Nonsteroidal
anti-inflammatories (flunixin 5%, 1.1mg/kg) were administered by mouth for 5 days, and mare and foal were confined to strict box rest for the first two
months.
Quinaquanone® (BoneKare™) was administered orally once daily at a dose rate of 10g/100 kg for the duration of three months.
Swelling and function did continue to improve slowly over the course of the following weeks.
Eight weeks after the original examination, no lameness could be observed in walk or trot and only mild distension of the joint capsule was present.
Flexion of the fetlock was non painful.
Radiographs taken at the time show healing well advanced with only slight differences in the mineral density still present (as judged on radiographs) and
the OCLL nearly completely eliminated.
Further Outcome
Mare and foal were returned to confined pasture for four weeks and put back into the herd after that.
The filly continued to progress well, showed no further lameness or swelling of the fetlock and did successfully take part in a breed show 14 weeks after
the original examination.

4. After Age: 4.5 months