1. LINKEDIN
E-MAIL
ichiaolee@gmail.com
MOBILE
+31 6 8179 9105
I-CHIAO LEE
EXPERIENCE
An experienced molecular microbiologist, who is
independent and responsible. Like to work in a well
organized manner with a creative mind. Perform
the best in a friendly environment.
PhD CANDIDATE
2011 - 2016
Wageningen University
The Netherlands
INTERNSHIP
2010
Genetwister
Technologies
The Netherlands
MASTER THESIS
2009 - 2010
TIFN Project
NIZO Food Research
The Netherlands
RESEARCH ASSISTANT
2006 - 2008
Academia Sinica IBMS
Taiwan
Focus on surface molecules, including proteins, CPS,
and teichoic acids, of probiotics
Study biochemical, physiological and
immunological properties of probiotic molecules
Focus on identifying molecular markers for apple
ripening using RNA isolation and qRT-PCR
techniques
Study the diversity of ripening within an apple tree
Focus on in vitro gastrointestinal tract survival of
probiotics
Identified a regulator improving the survival of
Lactobacillus plantarum WCFS1
EDUCATION
MSc BIOTECHNOLOGY
2008 - 2010
BSc LIFE SCIENCES
2001 - 2005
Wageningen University, The Netherlands
Specialized in molecular and cell biotechnology
Graduated with “cum laude”
National Taiwan University, Taiwan
Obtain solid knowledge in biology, genetics,
biochemistry, microbiology and molecular biology
Focus on improving surface protein expression
stability and quantity and on modifying enzyme
specificity using laboratory evolution
Skilled with mammalian cell tissue culture techniques
LANGUAGES SKILLS INTERESTS
CHINESE (Native)
ENGLISH (Fluent)
DUTCH (Basic A2)
CREATIVE
LOGICAL REASONING
INDEPENDENT
TENNIS and SWIMMING
PAINTING and POTTERY
BAKING and COOKING
2. PUBLICATION
MICROBIOLOGY
published ahead of
print: 17 Dec 2015
JOURNAL OF
BACTERIOLOGY
196 (2014) 9 p. 1671 -
1682
PHARMACOLOGICAL
RESEARCH
69 (2013) 1 p. 61 – 74
PLoS ONE
7 (2012) 7 e39053
PLoS ONE
8 (2013) 9 e75084
GtfA and GtfB are both required for protein O-
glycosylation in Lactobacillus plantarum
I-Chiao Lee, Iris I van Swam, Satoru Tomita, Pierre Morsomme,
Thomas Rolain, Pascal Hols, Michiel Kleerebezem, Peter A Bron
The quest for probiotic effector molecules—
Unraveling strain specificity at the molecular level
I-Chiao Lee, Satoru Tomita, Michiel Kleerebezem, Peter A. Bron
Modulation of Lactobacillus plantarum
Gastrointestinal Robustness by Fermentation
Conditions Enables Identification of Bacterial
Robustness Markers
Hermien van Bokhorst-van de Veen, I-Chiao Lee, Maria L Marco,
Michiel Wels, Peter A Bron, Michiel Kleerebezem
The B7-1 Cytoplasmic Tail Enhances Intracellular
Transport and Mammalian Cell Surface Display of
Chimeric Proteins in the Absence of a Linear ER
Export Motif
Yi-Chieh Lin, Bing-Mae Chen, Wei-Cheng Lu, Chien-I Su, Zeljko M
Prijovich, Wen-Chuan Chung, Pei-Yu Wu, Kai-Chuan Chen, Ting-
Yi Juan, I-Chiao Lee, Steve R Roffler
PATENT
WO2012150861 A1
2012
Probiotics with enhanced survival properties
Hermien VAN BOKHORST-VAN DE VEEN, I-Chiao LEE, Michiel
Wouter Wilhelmus WELS, Paulus DE VOS, Peter Allard BRON, Roger
Samuel BONGERS, Anne WIERSMA, Michiel KLEEREBEZEM
I-CHIAO LEE
Born on 21 FEBRUARY 1983
in TAIPEI, TAIWAN
Live now in
Lombardi 70, 6708LT Wageningen, The Netherlands
Characterisation of the transcriptional regulation of
the tarIJKL-locus involved in ribitol-containing wall
teichoic acid biosynthesis in Lactobacillus
plantarum
Satoru Tomita, I-Chiao Lee, Iris I van Swam, Sjef Boeren,
Jacques Vervoort, Peter A Bron, Michiel Kleerebezem
References
Prof. dr. Michiel Kleerebezem
michiel.kleerebezem@wur.nl
Dr. ir. Peter A Bron
peter.bron@nizo.com
