MODY is the name given to a collection of different types of inherited forms of diabetes that usually develop in adolescence or early adulthood. MODY stands for “Maturity-onset diabetes of the young” and was given that name in the past because it acted more like the adult type of diabetes (Type 2 Diabetes) but was found in young people. MODY limits the body’s ability to produce insulin, but is different than the juvenile type of diabetes (Type 1 Diabetes). When our bodies don’t produce enough insulin, it can increase blood glucose levels. High blood glucose levels lead to diabetes.

1. Memoona Arshad
Group 11
6th Semester
ISM-IUK
Presented to: Uvaidulaeva F.T.

2.  MODY is the name given to a collection of
different types of inherited forms of diabetes
that usually develop in adolescence or early
adulthood.
 MODY stands for “Maturity-onset diabetes of the
young” and was given that name in the past
because it acted more like adult type of diabetes
(Type 2 Diabetes) but was found in young people.
 MODY limits the body’s ability to produce insulin,
but is different than the juvenile type of
diabetes (Type 1 Diabetes).
 When our bodies don’t produce enough insulin, it
can increase blood glucose levels. High blood
glucose levels lead to diabetes.

3.  MODY is a rare form of diabetes which is
different from both type 1 and type 2
diabetes, and runs strongly in families.
 MODY is caused by a mutation (or change) in
a single gene.
 If a parent has this gene mutation, any child
they have, has a 50% chance of inheriting it
from them.
 If a child does inherit the mutation they will
generally go on to develop MODY before
they’re 25, whatever their weight, lifestyle,
ethnic group etc.

5.  Facts about MODY:
 MODY accounts for approximately 5 percent of all
U.S. diabetes cases.
 High blood glucose levels can damage body
tissues over time, including the eyes, kidneys,
nerves and blood vessels.
 MODY can show up at any age.

6.  People with MODY may have mild diabetes
symptoms.
 MODY symptoms tend to develop gradually,
so you may have no symptoms at first.
 That’s why MODY is often left undiscovered
until later in life or may be confused with
type 1 or type 2 diabetes.

7.  Symptoms may include:
 Frequent urination
 Thirst
 Dehydration
 Blurry vision
 Recurrent skin infections
 Recurrent yeast infections
 People with MODY may have high blood sugar
levels for many years before they experience
any symptoms.

8.  MODY is a “monogenic” disease. This means it is
caused by a single gene mutation.
 A number of different gene mutations can cause
MODY. If you have a family member with MODY,
you have an increased risk for the condition.
 While type 2 diabetes and MODY can both run in
families, individuals diagnosed with MODY often
have a family history of diabetes in successive
generations:
 meaning MODY is present in a
 Grandparent
 Parent
 child.

9.  A blood sugar test is the first step toward
diagnosing MODY.
 If your results indicate you have diabetes,
your doctor may order additional tests to
determine if you have MODY or another type
of diabetes, such as type 1 or 2.
 Since MODY is caused by a genetic mutation,
a genetic test can also help diagnose it.

10.  This testing will determine the exact type of
MODY.
 MODY is caused by a genetic mutation passed
on through the family.
 There’s currently no way to prevent or cure
it, but it can be managed, and predicted.
Knowledge is power.

12.  MODY is often treated with oral medications
or insulin injections, and some forms may
not require any treatment.
 The specific treatment may vary depending
on what genetic mutation caused the
condition.

13.  If you suspect your child has MODY, talk to
his or her health care provider as soon as
possible.
 An evaluation with a Pediatric
Endocrinologist experienced with MODY (like
those at Nationwide Children’s Hospital) can
be helpful.

14.  Diabetes MODY: Causes, Symptoms, Diagnosis
and Treatment (nationwidechildrens.org)
 DMSO_A_179793_O_F0002g.jpg (766×423)
(dovepress.com)
 fendo-09-00253-g001.jpg (964×664)
(frontiersin.org)
 Maturity onset diabetes of the young (MODY)
| Diabetes UK