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CELL CYCLE AND DIVISION
DR. GURMINDER RAWAL
• Describe cell division in eukaryotes
• Describe the basic properties of
chromosomes.
• Describe the key steps in the cell cycle.
• Identify and describe the main processes
in mitosis.
• Describe how the cell cycle is controlled
and define cancer.
• Cell Division: process by which a cell divides to
form two new cells (daughter cells)
• Three types of cell division, or cell reproduction
• Prokaryotes (bacteria)
• Binary fission→ divides forming two new
identical cells
• Eukaryotes
• Mitosis
• Cell or organism growth
• Replacement or repair of damaged cells
• Meiosis
• formation of sex cells, or gametes
CELL CYCLE
• Period of growth and DNA replication
between cell divisions
• Three phases:
• G1 Phase
• cell increases in size
• S Phase
• Replication of chromosomes
• Now two strands called sister
chromatids joined by a centromere
• G2 Phase
• organelles double
• new cytoplasm forms
• All other structures needed for mitosis
form
INTERPHASE
MITOSIS
• Process that divides cell nucleus to produce two new
nuclei each with a complete set of chromosomes
• Continuous process
• Four phases (PMAT)
• Prophase
• Metaphase
• Anaphase
• Telophase
PROPHASE
1. chromosomes visible (sister chromatids)
2. centrioles migrate to the poles (only in animals)
3. nuclear membrane disappears
4. spindle forms
METAPHASE
1.spindles attach to centromeres
2.chromosomes line up on the equator of the
cell
ANAPHASE
1.sister chromatids separate
2.centromeres divide
3.sister chromatids move to opposite poles
TELOPHASE
1. chromosomes uncoil • now chromatin
rearranges at the poles
2. nuclear membranes reform/reappear
3. spindle disappears
CYTOKINESIS
-Occurs at end of Mitosis
--division of the cytoplasm to form 2
new daughter cells
--organelles are divided
-Daughter cells are genetically identical
CANCER
Uncontrolled cell division leading to
tumours
No resting or gap phase
MEIOSIS
TAKES PLACE ONLY IN SEX
CELLS
RESULTS IN THE FORMATION OF
4 DAUGHTER CELLS
REDUCTIONAL DIVISION
THANK YOU

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Cell cycle and division

  • 1. CELL CYCLE AND DIVISION DR. GURMINDER RAWAL
  • 2. • Describe cell division in eukaryotes • Describe the basic properties of chromosomes. • Describe the key steps in the cell cycle. • Identify and describe the main processes in mitosis. • Describe how the cell cycle is controlled and define cancer.
  • 3. • Cell Division: process by which a cell divides to form two new cells (daughter cells) • Three types of cell division, or cell reproduction • Prokaryotes (bacteria) • Binary fission→ divides forming two new identical cells • Eukaryotes • Mitosis • Cell or organism growth • Replacement or repair of damaged cells • Meiosis • formation of sex cells, or gametes
  • 5. • Period of growth and DNA replication between cell divisions • Three phases: • G1 Phase • cell increases in size • S Phase • Replication of chromosomes • Now two strands called sister chromatids joined by a centromere • G2 Phase • organelles double • new cytoplasm forms • All other structures needed for mitosis form INTERPHASE
  • 6. MITOSIS • Process that divides cell nucleus to produce two new nuclei each with a complete set of chromosomes • Continuous process • Four phases (PMAT) • Prophase • Metaphase • Anaphase • Telophase
  • 7. PROPHASE 1. chromosomes visible (sister chromatids) 2. centrioles migrate to the poles (only in animals) 3. nuclear membrane disappears 4. spindle forms
  • 8. METAPHASE 1.spindles attach to centromeres 2.chromosomes line up on the equator of the cell
  • 9. ANAPHASE 1.sister chromatids separate 2.centromeres divide 3.sister chromatids move to opposite poles
  • 10. TELOPHASE 1. chromosomes uncoil • now chromatin rearranges at the poles 2. nuclear membranes reform/reappear 3. spindle disappears
  • 11. CYTOKINESIS -Occurs at end of Mitosis --division of the cytoplasm to form 2 new daughter cells --organelles are divided -Daughter cells are genetically identical
  • 12. CANCER Uncontrolled cell division leading to tumours No resting or gap phase
  • 13. MEIOSIS TAKES PLACE ONLY IN SEX CELLS RESULTS IN THE FORMATION OF 4 DAUGHTER CELLS REDUCTIONAL DIVISION