2. Moderators:
Professors:
Prof. Dr. G. Sivasankar, M.S., M.Ch.,
Prof. Dr. A. Senthilvel, M.S., M.Ch.,
Asst Professors:
Dr. J. Sivabalan, M.S., M.Ch.,
Dr. R. Bhargavi, M.S., M.Ch.,
Dr. S. Raju, M.S., M.Ch.,
Dr. K. Muthurathinam, M.S., M.Ch.,
Dr. D. Tamilselvan, M.S., M.Ch.,
Dr. K. Senthilkumar, M.S., M.Ch.
Dept of Urology, GRH and KMC, Chennai. 2
3. INTRODUCTION
TILL 1990-LAPROSCOPY, A DIAGNOSTIC TOOL
1990-LAP CHOLECYSTECTOMY
1991-LAP NEPHRECTOMY
3
Dept of Urology, GRH and KMC, Chennai.
4. HISTORY
• 1902-KELLING COINED "KOELIOSCOPIE“
• USED FILTERED AIR FOR
PNEUMOPERITONEUM IN DOG
• USED NITZE CYSTOSCOPE
• 1910-JACOBEUS OF STOCKHOLM-FIRST
ENDOSCOPIC ABDOMINAL INSPECTION IN
HUMAN-USED AIR
4
Dept of Urology, GRH and KMC, Chennai.
5. HISTORY
1920-ORNDOFF –RADIOLOGIST USED OXYGEN AS
INSUFFLANT-USED VALVED CANULA
1924-ZOLLIKOFER OF SWITZERLAND-CO₂ MORE
PRACTICAL CHOICE
5
Dept of Urology, GRH and KMC, Chennai.
6. CHOICE OF INSUFFLANT
CO₂ - most commonly used
Colourless ,non combustible,inexpensive
Quickly absorbed
High diffusion coefficient
Hypercarbia ,hypercapnia ,arrythmias
Stored in viscera,bone,muscle
6
Dept of Urology, GRH and KMC, Chennai.
7. CHOICE OF INSUFFLANT
Nitrous oxide
Less irritating, fewer acid base disturbances
&arrythmias
Supports combustion
Helium –inert, non combustible
Useful in COPD & poor hypercarbia tolerance
Decrease in tumor cell growth &
inflammatory reaction
7
Dept of Urology, GRH and KMC, Chennai.
8. CHOICE OF INSUFFLANT
Helium –high risk of gas embolism
Don’t use in extraperitoneal innsufflation-↑risk
of pneumothorax
Room air,oxygen-air embolism,combustion, intra
abdominal explosion
8
Dept of Urology, GRH and KMC, Chennai.
9. PHYSIOLOGICAL EFFECTS OF
PNEUMOPERITONEUM
Cardiovascular effects depends upon
Intra abdominal pressure
Patient position
co₂ absorption
Intravascular volume status
Pre existing cardiopulmonary status
Current medications
9
Dept of Urology, GRH and KMC, Chennai.
10. CARDIO VASCULAR EFFECTS
At low atrial pressure[normal or hypovolemic
state]→for pneumoperitoneum upto 20mmHg
→venous return is reduced
At high atrial pressure[hypervolemic state]→ IVC
resists↑IAP→venous return is actually enhanced
Net effect-↑TPR depressing cardiac function-more
pronounced in hypovolemic individuals
10
Dept of Urology, GRH and KMC, Chennai.
11. CARDIOVASCLAR EFFECTS
Cardiac index↓ by 50% of pre operative value within
5 minutes of insufflation,stabilises after 10 minutes
as systemic vascular resistance drops
EUROPEAN ASSOCIATION FOR ENDOSCOPIC
SURGERY PRACTICE GUIDELINES –
At IAP up to 15mmHg,↓venous return & cardiac output
is minimal without consequence in healthy individuals
11
Dept of Urology, GRH and KMC, Chennai.
12. CARDIOVASCULAR EFFECTS
Tachycardia,ventricular extrasystole-due to
hypercapnia
Brady arrythmia-due to peritoneal irritation and
vagal stimulation
Significance-clinical warning for
pneumothorax,hypoxia,gas embolism
Unreliability of CVP
12
Dept of Urology, GRH and KMC, Chennai.
14. RESPIRATORY EFFECTS
↑IAP→limits diaphragmatic movement →FRC↓,
pulmonary dead space unaffected→average peak
airway pressure needed to keep up constant tidal
volume increases parallel to ↑IAP
Non pressure related respiratory effects
Head down position ↓vital capacity
Pulmonary edema in ↑left atrial pressure
14
Dept of Urology, GRH and KMC, Chennai.
16. RENAL EFFECTS
Thorington&Schmidt found in dogs that
IAP>15mmHg - oliguria
IAP>30mmHg - anuria
Causes-↑renal vein pressure
Direct renal compression [Harman & co]
?ADH, ?AVP - unclear
16
Dept of Urology, GRH and KMC, Chennai.
17. RENAL EFFECTS
Renal vein& IVC pressure correlates with IAP
Renal artery pressure relatively unaffected by IAP
changes
With ↑IAP,increase in renal vascular resistance far
exceeded systemic vascular resistance
Direct effects on kidney plays major role
17
Dept of Urology, GRH and KMC, Chennai.
18. RENAL EFFECTS
In 1994 CHIU et al found that
Renal cortical blood flow↓ with↑IAP
Renal medullary blood flow↑upto 20mmHg &↓
>20mmHg
Low dose dopamine[2μg/kg] can prevent dip in urine
output [PEREZ et al,2002 ]
Summary-At IAP 10-15mmHg urine output ↓
significantly & associated with↓ RBF
18
Dept of Urology, GRH and KMC, Chennai.
19. INTRACRANIAL PRESSURE
Monroe –kellie doctrine hypothesis
Vascular,CSF,osseous,parenchymal
Este-Mcdonald colleagues
↑IAP→↓venous outflow from spinal cord via
lumbar & pelvic plexuses → ↑intracranial
pressure
19
Dept of Urology, GRH and KMC, Chennai.
20. INTRACRANIAL PRESSURE
Rosenthal & colleagues postulated that ,↑ICP is by
two phase mechanism
Early passive venous effect
Late active arterial effect
Acute elevation of ICP elicits CUSHING REFLEX
Todate ,no neurological sequelae in normal patients
20
Dept of Urology, GRH and KMC, Chennai.
22. VISCERAL EFFECTS
Decreased blood flow noted in mesentry,
liver,pancreas,stomach,spleen, small& large intestine
Increased blood flow in adrenals
No ↑ incidence of GE reflux/regurgitation
22
Dept of Urology, GRH and KMC, Chennai.
23. ACID BASE METABOLIC
EFFECTS
Co₂ absorbed from peritoneal membrane in TPL
&preperitoneal adipose& connective tissue in RPL
scopy
Co₂ absorption is more, during initial 30-60 minutes
of the procedure
Hypercarbia & respiratory acidosis is more common
ABG must in-lap >1 hour,COPD,RF,CCF.
23
Dept of Urology, GRH and KMC, Chennai.
24. ACID BASE METABOLIC
EFFECTS
Ideally End tidal co₂ & o₂ should be monitored using
a capnometer.
With ↑ in end tidal co₂, adjust the respiratory rate &
tidal volume.
24
Dept of Urology, GRH and KMC, Chennai.
25. HEMODYNAMIC EFFECTS IN RELATION
TO PATIENT POSITION
parameter Head up Head down
Heart Rate
MAP
SVR
CO
ICP
25
Dept of Urology, GRH and KMC, Chennai.
26. HARMONAL & METABOLIC
EFFECTS
Increase in βendorphin,cortisol,prolactin,
epinephrine,nor epinephrine,dopamine.
Reduced tissue loss of amino nitrogen in LAP
responsible for rapid convalescense
Lap procedures generally result in less
immunosuppression
26
Dept of Urology, GRH and KMC, Chennai.
27. COMPLICATIONS WITH VERESS
NEEDLE PLACEMENT
Pre peritoneal placement
Steep pressure rise
Unequal abdominal distension
Check –signs of proper entry
Negative aspiration
Easy irrigation of saline
Negative aspiration of saline
Positive drop test, normal advancement test
27
Dept of Urology, GRH and KMC, Chennai.
28. VASCULAR INJURIES
First sign-blood appearing at hub of the needle
Prevention-direct needle towards hollow of pelvis
Blunt subcutaneous fat separation, grasp & stabilise
anterior fascia before puncture
Non umbilical site of entry
Use of blunt trochars
28
Dept of Urology, GRH and KMC, Chennai.
29. VISCERAL INJURIES
Initial sign-aspiration of blood, urine, bowel
contents/high pressure on insufflations
Management-reintroduce at different site
Bleeding from liver/spleen need argon beam
coagulator or apply surgical hemostat[fibrin
glue]
Bowel/bladder entry needs only needle
withdrawal
29
Dept of Urology, GRH and KMC, Chennai.
30. VISCERAL INJURIES
Prevention-NG tube
Foley catheter
Stabilize abdominal wall fascia
Check proper signs of peritoneal entry
30
Dept of Urology, GRH and KMC, Chennai.
31. COMPLICATIONS OF
INSUFFLATION
Bowel insufflations
Gas embolism-mc cause is puncture of blood
vessel/organ
first sign-acute cardiovascular collapse
Dysrhythmias, tachycardia, cyanosis,
pulmonary edema
Millwheel precordial murmur
31
Dept of Urology, GRH and KMC, Chennai.
32. COMPLICATIONS OF
INSUFFLATION
Management of gas embolism
Cessation of insufflations
Desufflate peritoneal cavity
Turn pt in left lateral decubitus position
Hyperventilate with 100% oxygen
Advance central line into Rt heart & aspirate gas
32
Dept of Urology, GRH and KMC, Chennai.
33. COMPLICATION OF
INSUFFLATION
Barotrauma-prolonged elevated pressure [>15mm hg]
Cause-malfunction of insufflator
Insufficient pressure monitoring
PEEP ventilation –rupture of pulmonary bulla
Initial sign- hypotension-↓ venous return from IVC
compression
33
Dept of Urology, GRH and KMC, Chennai.
34. BAROTRAUMA
Management- desufflate the abdomen
Replace malfunctioning insufflator
Reinitiate pneumoperitoneum
Subcutaneous emphysema-cause
Improper veress needle placement
Leakage of co₂ around ports
Problem resolves in 2 to 3 post op days
34
Dept of Urology, GRH and KMC, Chennai.
35. PNEUMOPERICARDIUM
Cause-gas leak along major blood vessels,through
congenital defects
Incidence-0.8%
Diagnosis rarely made during procedure, usually
made in recovery room with CXR
Treatment-interrupt procedure
Desufflate abdomen
pericardiocentesis
35
Dept of Urology, GRH and KMC, Chennai.
37. Complications of blind
placement of first trochar
Injury to GI organs-small/large intestine injury
Injury to intra abdominal vessels-0.11%-2%
More common in retroperitoneoscopy
Aorta & common iliac vessels-mc
In intestinal adhesions- mesentric vessel of
fixed loop, may be injured
First sign-hypotension, tachycardia
Treatment-emergency laporotomy
37
Dept of Urology, GRH and KMC, Chennai.
38. COMPLICATIONS
Prevention-special care in children
Look for CT scan if available
IAP may be temporarilyraisedto25mmHG
Avoid trochar through scar
treatment-vascular repair
38
Dept of Urology, GRH and KMC, Chennai.
39. INJURY TO URINARY TRACT
Mc with trochar passage
Incidence-0.02% to8.3%
Mc-bladder injury
Sign-pnematuria, macroscopic haematuria
Confirm-intra vesical installation of indigo carmine
Treatment-lap/open surgical repair[don’t allow to
heal on their own]
39
Dept of Urology, GRH and KMC, Chennai.
40. COMPLICATIONS OF SECONDARY
TROCHAR PLACEMENT
Bleeding at cannula site
Position related problems,
crossing swords & striking
handles
40
Dept of Urology, GRH and KMC, Chennai.
41. COMPLICATIONS OF GA
Cardiac arrythmias & cardiac arrest
MC - sinus tachycardia, bradyarrythmias
Causes- CO₂ insufflation, ↑ vagal tone
Changes in BP
Aspiration of gastric contents
Hypothermia [0.3⁰c for each 50L of co₂ insufflated]
↑bleeding tendency, ↑adrenergic response,
prolonged recoverytime, ↑early post op MI.
41
Dept of Urology, GRH and KMC, Chennai.
42. Complications of lap surgery
Bowel injury-Electro surgical etiology
Inappropriate direct activation
Coupling to another instrument
Capacitative coupling
Insulation failure
42
Dept of Urology, GRH and KMC, Chennai.
43. Bowel injury-management
Intra op – looks as white spots in serosa
Full extent of bowel necrosis-takes 18 days
Intraperitoneal free air unreliable
Early or late
Monopolar thermal injury/bipolar thermal injury
Preventive measures
43
Dept of Urology, GRH and KMC, Chennai.
44. BLADDER INJURY
Predisposing factors-prior pelvic/bladder surgery,
prior RT, endometriosis, bladder diverticula,
amyloidosis
Management- intra op or post op diagnosis
In post op- extraperitoneal or intraperitoneal
44
Dept of Urology, GRH and KMC, Chennai.
45. URETERAL INJURY
As a result of monopolar cautery around ureter
Common in lap hysterectomy-1%,lap endometrial
ablation,pelvic lymphadenectomy,lap radical
prostatectomy
Management-intra op or post op.
45
Dept of Urology, GRH and KMC, Chennai.
46. NERVE INJURIES
Invariably due to patient positioning
Brachial plexus appears to be at high risk
Schiatic nerve –stretching along superior leg when pt
in lateral decubitus position
Femoral nerve-lateral rotation& abduction of hip
46
Dept of Urology, GRH and KMC, Chennai.
47. EARLY POST OP
COMPLICATIONS
Acute hydrocele
Scrotal&abdominal ecchymosis
Pain
Incisional hernia->10mm port –in adults
Wound infection
DVT
rhabdomyolysis
47
Dept of Urology, GRH and KMC, Chennai.
48. DEEP VEIN THROMBOSIS
Immediate heparin anticoagulation
Pneumatic sequential compression devices
Unfractionated heparin 5000 units ,2 hours pre op
and 12th hourly post op
48
Dept of Urology, GRH and KMC, Chennai.
49. RHABDOMYOLYSIS
Mc after RPL procedures
Incidence -1%
Mc in male –LAP renal procedures>5hrs
Severe pain in downside hip area, brown urine,
CPK>5000units/dl
Hydration & alkalinisation, extended physiotheraphy.
Avoid kidney rest, hypotension ,gel/fluid pad.
49
Dept of Urology, GRH and KMC, Chennai.
50. LATE POST OP COMPLICATIONS
Lymphocele – mc after pelvic procedures, take
weeks to develop, present as mass/pressure effect –
CT- Percutaneous drainage/lap marsupialization.
Chylous ascites- mc after left sided retroperitoneal
surgeries,-abdominal distension-low fat medium
chain triglyceride diet-observe. CT scan reveal
ascites, tap & analyse.
Treatment- somatostatin, suturig of leaky lymphatic
channel.
50
Dept of Urology, GRH and KMC, Chennai.
51. PNEUMORETROPERITONEUM
Higher chance of subcutaneous emphysema,
pnemothorax and pneumomediastinum[7%],
vascular injuries
Less chance of intraperitoneal visceral injury, port
site hernia.
51
Dept of Urology, GRH and KMC, Chennai.