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ANESTHESIA FOR
ROBOTIC SURGERY
DR ZIKRULLAH
 Physiological Impact
 Complications
 Anesthetic Management
Console Patient side cart Vision system
SURGICAL PROCEDURES
EMPLOYED:
 Cardiac : LIMA takedown with LAD
anastomosis, Mitral valve repair.
 Thoracic : Mediastinal mass, Lobectomy.
 Upper Abdominal : Reflux surgery, Bariatric
surgery, Diaphragmatic and Esophageal hernia
surgery, Esophagectomy, Cholecystectomy.
 Mid Abdominal : Nephrectomy, Adrenalectomy,
Colorectal.
 Pelvic; Prostatectomy, Hysterectomy,
Cystectomy, Sacrocopolpexy, Myomectomy,
Endometriosis.
 Head and Neck; Thyroidectomy, Cancer surgery.
PHYSIOLOGICAL IMPACT
PHYSIOLOGY OF ROBOTIC ASSISTED
PELVIC SURGERY
15 – 20 degree
Trendelenburg
PCWP > 18 mm Hg
CO fell by 1030%
12 mm Hg
Pneumoperitoneum
 MAP increased 25%
 CVP, MPAP, PCWP
unchanged
 SVR increased 20%
 HR, SV unchanged
 Mesenteric, hepatic and
renal blood flow
decreased.
Cardiovascular Effects of Trendelenburg and
Pneumoperitoneum
PHYSIOLOGY OF ROBOTIC
ASSISTED PELVIC SURGERY
45o Trendelenburg with Pneumoperitoneum for
robotic assisted pelvic surgery.
CVP, MPAP, PCWP doubled
Blood pressure increased by 25%
SVR initially increased, then normalized
HR, SV unchanged
RV and LV stroke work increased by 65%
PHYSIOLOGY OF ROBOTIC
ASSISTED PELVIC SURGERY
 Elevation in filling pressures was associated with 25%
increase in
early transmitral flow (early passive LV filling before
atrial kick).
 Preservation of isovolemic relaxation time and
deceleration time would indicate diastolic function is
well preserved.
 Diastolic function as an early indication of ischemia
indicate increases in filling pressure, afterload and
stroke work are well tolerated.
Echocardiographic measures of left and right
ventricle function indicate preserved or slight
increase in stroke volume.
PHYSIOLOGY OF ROBOTIC
ASSISTED PELVIC SURGERY
 Healthy nonanesthetized volunteers experienced
a rise in heart rate without significant change in
blood pressure or cardiac output.
 Patients with underlying ischemic heart
disease saw a rise in blood pressure and
cardiac output with a fall in heart rate.
PHYSIOLOGY OF ROBOTIC
ASSISTED PELVIC SURGERY
Pulmonary Effects of Trendelenburg and
Pneumoperitoneum
 Reduced total lung capacity, compliance and
increase airway pressures.
 A 15 mm Hg pneumoperitoneum yields a 9 mm
Hg rise in intrathoracic pressure.
 The diaphragm is shifted cephalad and FRC is
reduced more than 50%. Lung volume
approaches closing capacity with resultant
atelectasis and shunt.
 Arterial oxygenation falls.
 Minute ventilation must increase to offset
hypercarbia.
PHYSIOLOGY OF ROBOTIC
ASSISTED PELVIC SURGERY
Ventilation modes and respiratory variables during TrP
and PPN
 Volume Control and Pressure Control at equal tidal
volumes.
 Pressure Control yields better compliance and
lower airway pressures.
 There were no statistically significant differences in
hemodynamics.
 RR increased nearly 50% to maintain normal pCO2
levels.
PHYSIOLOGY OF ROBOTIC
ASSISTED PELVIC SURGERY
Effects of PEEP during TrP
and PPN
Application of 5 mm Hg PEEP
increases FRC, elevating
lung volumes above
closing capacity.
 Less atelectasis.
 Compliance improves.
 Arterial oxygenation
improves.
Pneumoperitoneum with
addition of PEEP may
abruptly drop CO.
Acta Anaesthesiologica Scandinavica, 2005, 49, 778
783
PHYSIOLOGY OF ROBOTIC ASSISTED
PELVIC SURGERY
Abdominal Effects of Elevated Intraabdominal
Pressure and
Pneumoperitoneum
 Blood is mobilized out of the abdominal viscera, causing
an acute increase in cardiac preload.
 Blood flow through the mesenteric arteries decreases,
resulting in a slow gradual rise in mucosal pH related to gut
ischemia.
 Portal vein, hepatic vein and hepatic tissue perfusion all
decrease with associated rise in transaminases.
 Blood flow in both the renal cortex and medulla decreases with
resultant fall in urine output.
 Elevated intraabdominal pressure may decrease return
through the IVC and may result in delayed drop off in cardiac
preload.
PHYSIOLOGY OF ROBOTIC
ASSISTED PELVIC SURGERY
Effect of Elevated Pressure Pneumoperitoneum on
Neurohormonal regulation.
 Rise in vasopressin and norepinephrine.
 Activation of reninangiotensin system.
PHYSIOLOGY OF ROBOTIC
ASSISTED PELVIC SURGERY
Cerebral Hemodynamics during steep Trendelenburg and
Pneumoperitoneum
 Headdown positioning increases CVP and thus impairs
venous drainage of the head.
 The elevation of hydrostatic forces can lead to an
increase in extracellular water and perivascular
edema.
 Development of cerebral edema and elevations in ICP may
lead to increased cerebrovascular resistance and reduced
cerebral blood flow.
 ICP may be further elevated by increases in cerebral blood
volume
related to hypercarbia.
 Impedance of drainage of the lumbar venous system
secondary to the elevated intraabdominal pressure may
decrease reabsorption of CSF and lead to a rise in ICP.
PHYSIOLOGY OF ROBOTIC
ASSISTED PELVIC SURGERY
Intraocular Pressure Dynamics during steep Trendelenburg
and Pneumoperitoneum
Major determinants of IOP
Aqueous humor flow
Choroidal blood volume
CVP
Extraocular muscle tone
Intraoperative hypertension, hypercarbia, position
and elevation in CVP may lead to
elevated IOP.
COMPLICATIONS
1.3% postop anemia
1% postop transfusion
3% corneal abrasion
6 % reoperation
 Bleeding
 Bowel injury
 Hernia
0.2% PE
ROBOTIC SYSTEM MALFUNCTION
Review of 1,914 reports of da Vinci malfunction reported
to FDA.
 Instrument failures comprise the largest group.
Arcing
Fragmentation
 Patient side cart malfunctions.
 Console malfunction.
 Endoscope malfunction.
ROBOTIC SYSTEM MALFUNCTION
COMPLICATIONS OF PNEUMOPERITONEUM
Subcutaneous Emphysema
 Common ~5%.
 Usually self limited.
 Increases rate of CO2
uptake.
Progressive mixed
acidosis.
o Continued postoperative absorption.
 Further investigation
Pneumothorax
Capnothorax
Pneumomediastinum
COMPLICATIONS OF ACCESS
Aortic injury. Robotically
repaired.
Journal of Endourology; 2011, Volume 25, Number 2, 235238
INNOCENT BYSTANDER INJURY
Iliac Vein
hemorrhage.
Bowel
perforation.
World Journal of Urology; Volume 26, Number 6, 595
602
Yonsei Medical Journal; 2011, Volume 52, Number 2, 365368
CARDIOVASCULAR COMPLICATIONS
Myocardial Infarction
 Patient had preexisting coronary artery disease
 Coronary stents insitu
 Taken off antiplatelet,
drugs prior to surgery,
Congestive heart failure,
refractory hypertension.
CARDIOVASCULAR COMPLICATIONS
Cardiac Arrest
 Robotic arm pressed against patients neck
Vagal nerve mediated response; bradycardia,
nodal, atrioventricular dissociation, asystole.
Catecholamine mediated response; sinus tach,
ventricular extrasystole.
PULMONARY COMPLICATIONS
Pulmonary Edema
 IAP raised from 15 to 20 mm Hg
 30 degree Trendelenburg
 CVP 31 cm H2O
 Compression of lung
 Absorption of crystalloid irrigating fluid
Barotrauma, atelectasis, pneumothorax, capnothorax.
NEUROMUSCULAR COMPLICATIONS
Compartment Syndrome
 LithotomyTrendelenburg
 Surgery over 4.5 hours
 Muscular calf muscles
 Blood loss
 Hypotension
 Vasoactive drugs
 Fibrate monotherapy
 Elevated BMI
CNS COMPLICATIONS
Paradoxical Cerebral Air Embolism
 45 degree Trendelenburg
 CVP 816
ANESTHETIC
CARE
PREOPERATIVE
History and Physical Exam
 General Medical Assessment.
 Patient specific factors which may be of
concern with prolonged
pneumoperitoneum or extremes of
positioning.
 Patient specific factors which may
contribute to a difficult procedure.
 Testing, blood work and consent driven by
standard
process.
 Nervous system evaluation
 CVA
 Aneurysm
 Elevated ICP
Hydrocephalus, VP shunt
Head trauma
 Ocular pathology
Glaucoma
 Preexisting neuropathy or susceptibilities
Diabetes, chemotherapy, peripheral
vascular disease
Extremes of body size, surgery lasting
> 3 hours.
 Cardiovascular
Evaluation
 Cardiomyopathy
 CAD or MI by history or symptoms
Angina
Untreated obstructive coronary
disease
 Cardiac murmurs
Evaluated by Echo
Moderate or severe regurgitant
valvular lesions
 Peripheral vascular disease
 Pulmonary Evaluation
 COPD
 Bullous emphysema
 Spontaneous pneumothorax
 Reactive airway disease
 Prolonged pneumoperitoneum is
contraindicated in moderate to severe
disease states.
 Renal disease
 Renal insufficiency
may benefit from protective
strategies.
 Renal failure
Contraindication to prolonged
pneumoperitoneum.
 Lithotomy and Trendelenburg positioning
 For every one hour spent in lithotomy, risk of
nerve injury increases 100 fold.
 Risks of compartment syndrome
Myopathy, Fibrates or statin use, Muscular calf,
PVD.
 Lateral decubitus positioning
 Cervical spine disease
 Back pain, radiculopathy
 Age
 Increased risk of post operative ventilation (> 65
years old)
 Increased risk of ICU admission
 Obesity
 Correlated with longer operative times.
 Higher ventilatory pressures and risk of
barotrauma.
 Lower intraoperative oxygenation.
 Associated with OSA, airway difficulty, diabetes.
 Diaphragmatic hernia
 Coagulopathy
 Patient specific factors making for a difficult
operation.
 Morbid obesity
 Adhesions
 Prior surgery
 Prior infection
 Prior radiation
 Procedure specific
PREOPERATIVE
 stop all antiplatelet medications for 1 week
and ASA in radical prostatectomies
 1 day before surgery should adhere to clear
liquid diet.
 Night before use laxative suppositories.
 Bowel prep not used.
 NPO at midnight.
 Psychological preparation
 Should be aware of plan for early discharge.
 Informed of known side effects and
complications which are within the realm of
normal and do not affect recovery or
discharge.
PREOPERATIVE
 Blood Type and Antibody Screen.
 Peripheral IV access x 2.
 Premedication for multimodal
analgesia.
 Antibiotic order.
 Antigastric prophylaxis with Ranitidine and
sodium citrate.
CONDUCT OF ANESTHESIA
 Monitors
 Standard ASA monitors.
 Orbicularis oculi twitch response is most
similar to the adductor pollicis in onset and
duration.
CONDUCT OF ANESTHESIA
 Monitors for special circumstances
 Invasive monitors are indicated with inexperienced
robotic programs or while a surgeon is
inexperienced with a particular procedure.
 Arterial blood pressure monitoring is indicated for
patients with cardiac or pulmonary disease, with all
cystectomy or nephrectomy operations and
procedures planned for greater than four hours.
 Central line placement for the purpose of
resuscitative drug administration warrant re-
consideration if robotic surgery is the appropriate
approach.
CONDUCT OF ANESTHESIA
 Monitors for special circumstances
 Cardiac output monitoring is indicated in
cardiomyopathy.
Esophageal doppler has been advocated by
several authors.
 TransEsophageal Echocardiography is the most
advantageous monitor to add in the event of
unexpected hemodynamic collapse.
CONDUCT OF ANESTHESIA
 Induction
 Intubation
 Avoid hemodynamic response to
laryngoscopy.
 Note the depth of ETT relative to the carina.
 Ensure endotracheal tube is well secured.
CONDUCT OF ANESTHESIA
 General Endotracheal Anesthesia
 Secure airway.
 Controlled mechanical ventilation to properly
handle carbon dioxide absorbed through
pneumoperitoneum.
 Continuous neuromuscular blockade until
robot is undocked.
 Nitrous oxide +/.
 Low dose opiod.
 Neuraxial techniques not currently recommended.
 Thoracic epidural is associated with earlier
return of bowel function and of benefit in
cystectomy with ileal conduit.
Once the robot is docked there is no further
repositioning of the patient or bed without undocking the
robot.
Care must be taken the patient is positioned well enough
to tolerate up to 9 hours in the final position.
POSITIONING
Sequence for Lithotomy –Steep Trendelenburg
positioning
 Awake tucking of arms.
 Induction and intubation.
 Eyes padded. Tegaderm applied.
 Orogastric tube passed and gut decompressed.
 Ensure face will be clear of equipment;
 protective padding placed if necessary.
 Fingers protected from bed hinges.
 Legs raised simultaneously to bilateral stirrups.
 Apply nerve stimulator.
 Apply the bean bag ensuring no pressure points created.
 Test the security of patient to bed in steep TrP.
 Visualize face at all times.
INTRAOPERATIVE MANAGEMENT
 Ventilation
 A fall in compliance will complicate ventilation in TrP.
 Pressure Control Ventilation is recommended.
 PEEP [5 cm H2O] is recommended.
 Mild hyperventilation to avoid development of hypercarbia
and resultant metabolic and respiratory acidemia.
 Suggested minute ventilation is 1215 L/min.
 Alternatively use twice the prePPN minute ventilation.
 All changes in minute ventilation should be made
through manipulation of respiratory rate, not tidal
volume.
 ETCO2 should plateau by 1520 min.
 Appropriate to correlate to ABG in at risk patients.
 Anticipate endobronchial intubation or mechanical
obstruction in PPN.
INTRAOPERATIVE MANAGEMENT
 Perfusion
 Patients at risk of cardiomyopathy may benefit from
arteriovasodilators
 ie nicardipine
 Patients at risk of demand ischemia may benefit from alpha 2
agonist
 ie clonidine or dexmeditomidine
 Patients at risk of elevated intracranial pressure should be
protected
 mannitol, fluid restriction, normocapnia.
 Patients at risk of renal insufficiency should be protected
 Mannitol, nicardipine infusion, warm insufflation.
 Patients at risk of compartment syndrome should have calves
checked for tissue tugor and consider repositioning legs every
two hours.
INTRAOPERATIVE MANAGEMENT
 Neuromuscular blockade
 Absolute requirement for paralysis during
period which the robot is docked to the
patient.
 Use of continuous infusion has been
advocated.
 Monitoring of neuromuscular function by
train of four has been recommended.
INTRAOPERATIVE MANAGEMENT
 Temperature management
 Over the body forced air warmer above the xiphoid
 Isothermic carbon dioxide
INTRAOPERATIVE MANAGEMENT
 Fluid Management
 Excess fluid administration in steep TrP can lead to
facial edema with associated swelling of conjunctiva
and/or airway.
In prostatectomy, fluid restriction is warranted with
a goal of less than 1 liter IVF up to the completion
of the urethrovesical anastamosis.
After the urethrovesical anastamosis is
complete, liberalize fluid administration with the
goal of an additional 1 liter IVF by the end of
surgery.
 Always discuss concerns regarding fluid status with
surgeon.
 Have a lower than usual threshold for colloid
administration.
INTRAOPERATIVE MANAGEMENT
 Other intraoperative issues.
 Thromboprophylaxis
Elevation of the legs and placement to stirrups
raises the risk of DVT formation.
Intermittent Compression Devices lower DVT
risk and promote venous return to the heart
even with elevated intraabdominal pressure.
Preoperative SQ Heparin is standard practice
INTRAOPERATIVE MANAGEMENT
 Other intraoperative issues.
 Oral, facial and ocular burns have been associated with
regurgitation of stomach acid in TrP.
Orogastric decompression
H2 blockade
Carefully cover the eyes with Tegaderm.
 Antiemetic prophylaxis.
 Surgical Local Anesthetic
Trocar / port site infiltration 5 – 10 mL
Intraperitoneal installation 40 mL
 Irrigation fluid and urine commonly overwhelm blood in
the suction canisters making estimating blood loss
difficult.
PNEUMOPERITONEUM
Recommendations state “to use the lowest IAP allowing
adequate exposure … to avoid more than 12 mm Hg combined
with Trendelenburg positioning because it reduces pulmonary
compliance … and worsens ventilationperfusion impairment.”
 Low pressure 57 mm Hg
 Splanchnic perfusion preserved.
 Normal 12 mm Hg
 High 1520 mm Hg;
 may be enacted to tamponade venous bleeding.
 Anticipate bradycardia [asystole] with raising
pneumoperitoneum and initial placement of ports.
 Reassess for bilateral breath sounds to exclude
endobronchial intubation.
EMERGENCY PLANNING
 Have a low threshold for advanced monitoring and
arterial blood gas analysis.
 Cardiovascular instability warrants immediate
termination of PPN and TrP and, if refractory,
investigation with transesophageal echo.
 Advocate for aborting or suspending robotic
technique if signs indicate patient is not tolerating
steep TrP.
 Have a plan for management of massive hemorrhage.
 Be prepared to emergently undock robot.
 It is acceptable to cardiovert with the robot docked.
PREPARING FOR EMERGENCE
 Terminate neuromuscular blocker administration
once the robot is undocked.
 Use “sigh” breath or recruitment maneuvers to
reverse interval atelectasis from PPN or
endobronchial intubation.
 Elevate the patient’s head as soon as is permissible.
 Maintain mechanical ventilation and
hyperventilation until the patient awakens.
EXTUBATION
Anticipate a delay in awakening.
 Elevate the head of bed.
 Assess for subcutaneous emphysema.
 Assess for head and neck swelling, and scleral and
periorbital edema.
 Perform endotracheal tube cuff “leak test”.
 Ensure patient is following commands.
 Auscultate for clear, bilateral breath sounds.
 Ensure return of neuromuscular function.
 If in any doubt of appropriate wakefulness, adequacy of
ventilation, or ability to maintain a patent airway - do not
extubate.
POSTOPERATIVE
 Standard monitors for recovery of general
anesthesia.
 Maintain elevation of the head of bed.
 Hemoglobin analysis is indicated.
 Blood gas analysis is indicated in the presence of
hypoxia, delirium, hyperventilation or as follow up to
intraoperative ABG abnormality.
 Chest radiographs are indicated when significant
subcutaneous emphysema is present, or if there
are signs suggesting pneumothorax, or
unexplained low oxygen saturations.
POSTOPERATIVE
 Patients should require little additional narcotic.
 Reported pain should be evaluated as
consistent with procedure, referred from
phrenic nerve irritation, or related to
intraoperative positioning.
 Moderate or severe pain should prompt
evaluation by surgeon.
 Mental status should be evaluated to
rule out hypercarbia, elevated intracranial
pressure and stroke.
 Positional neuropathies if any, need to be looked
into.
 Oliguria should be promptly treated with 500 mL
bolus of crystalloid and then continue at150 mL/Hr.
Chief Concerns for Anesthesia during Robotic
Assisted Surgery
 Limitation of access.
 Inexperience of surgeon, assistants or team.
 Extremes of patient positioning.
 Length of case.
 Hypothermia.
 Respiratory and hemodynamic effects of
pneumoperitoneum and
extremes of positioning.
 Occult blood loss.
 Unsuspected visceral injury.
Thank
you

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ANESTHESIA FOR ROBOTIC SURGERY: PHYSIOLOGICAL IMPACT, COMPLICATIONS AND MANAGEMENT

  • 2.  Physiological Impact  Complications  Anesthetic Management
  • 3. Console Patient side cart Vision system
  • 4.
  • 5.
  • 6. SURGICAL PROCEDURES EMPLOYED:  Cardiac : LIMA takedown with LAD anastomosis, Mitral valve repair.  Thoracic : Mediastinal mass, Lobectomy.  Upper Abdominal : Reflux surgery, Bariatric surgery, Diaphragmatic and Esophageal hernia surgery, Esophagectomy, Cholecystectomy.  Mid Abdominal : Nephrectomy, Adrenalectomy, Colorectal.  Pelvic; Prostatectomy, Hysterectomy, Cystectomy, Sacrocopolpexy, Myomectomy, Endometriosis.  Head and Neck; Thyroidectomy, Cancer surgery.
  • 8. PHYSIOLOGY OF ROBOTIC ASSISTED PELVIC SURGERY 15 – 20 degree Trendelenburg PCWP > 18 mm Hg CO fell by 1030% 12 mm Hg Pneumoperitoneum  MAP increased 25%  CVP, MPAP, PCWP unchanged  SVR increased 20%  HR, SV unchanged  Mesenteric, hepatic and renal blood flow decreased. Cardiovascular Effects of Trendelenburg and Pneumoperitoneum
  • 9. PHYSIOLOGY OF ROBOTIC ASSISTED PELVIC SURGERY 45o Trendelenburg with Pneumoperitoneum for robotic assisted pelvic surgery. CVP, MPAP, PCWP doubled Blood pressure increased by 25% SVR initially increased, then normalized HR, SV unchanged RV and LV stroke work increased by 65%
  • 10. PHYSIOLOGY OF ROBOTIC ASSISTED PELVIC SURGERY  Elevation in filling pressures was associated with 25% increase in early transmitral flow (early passive LV filling before atrial kick).  Preservation of isovolemic relaxation time and deceleration time would indicate diastolic function is well preserved.  Diastolic function as an early indication of ischemia indicate increases in filling pressure, afterload and stroke work are well tolerated. Echocardiographic measures of left and right ventricle function indicate preserved or slight increase in stroke volume.
  • 11. PHYSIOLOGY OF ROBOTIC ASSISTED PELVIC SURGERY  Healthy nonanesthetized volunteers experienced a rise in heart rate without significant change in blood pressure or cardiac output.  Patients with underlying ischemic heart disease saw a rise in blood pressure and cardiac output with a fall in heart rate.
  • 12. PHYSIOLOGY OF ROBOTIC ASSISTED PELVIC SURGERY Pulmonary Effects of Trendelenburg and Pneumoperitoneum  Reduced total lung capacity, compliance and increase airway pressures.  A 15 mm Hg pneumoperitoneum yields a 9 mm Hg rise in intrathoracic pressure.  The diaphragm is shifted cephalad and FRC is reduced more than 50%. Lung volume approaches closing capacity with resultant atelectasis and shunt.  Arterial oxygenation falls.  Minute ventilation must increase to offset hypercarbia.
  • 13. PHYSIOLOGY OF ROBOTIC ASSISTED PELVIC SURGERY Ventilation modes and respiratory variables during TrP and PPN  Volume Control and Pressure Control at equal tidal volumes.  Pressure Control yields better compliance and lower airway pressures.  There were no statistically significant differences in hemodynamics.  RR increased nearly 50% to maintain normal pCO2 levels.
  • 14. PHYSIOLOGY OF ROBOTIC ASSISTED PELVIC SURGERY Effects of PEEP during TrP and PPN Application of 5 mm Hg PEEP increases FRC, elevating lung volumes above closing capacity.  Less atelectasis.  Compliance improves.  Arterial oxygenation improves. Pneumoperitoneum with addition of PEEP may abruptly drop CO. Acta Anaesthesiologica Scandinavica, 2005, 49, 778 783
  • 15. PHYSIOLOGY OF ROBOTIC ASSISTED PELVIC SURGERY Abdominal Effects of Elevated Intraabdominal Pressure and Pneumoperitoneum  Blood is mobilized out of the abdominal viscera, causing an acute increase in cardiac preload.  Blood flow through the mesenteric arteries decreases, resulting in a slow gradual rise in mucosal pH related to gut ischemia.  Portal vein, hepatic vein and hepatic tissue perfusion all decrease with associated rise in transaminases.  Blood flow in both the renal cortex and medulla decreases with resultant fall in urine output.  Elevated intraabdominal pressure may decrease return through the IVC and may result in delayed drop off in cardiac preload.
  • 16. PHYSIOLOGY OF ROBOTIC ASSISTED PELVIC SURGERY Effect of Elevated Pressure Pneumoperitoneum on Neurohormonal regulation.  Rise in vasopressin and norepinephrine.  Activation of reninangiotensin system.
  • 17. PHYSIOLOGY OF ROBOTIC ASSISTED PELVIC SURGERY Cerebral Hemodynamics during steep Trendelenburg and Pneumoperitoneum  Headdown positioning increases CVP and thus impairs venous drainage of the head.  The elevation of hydrostatic forces can lead to an increase in extracellular water and perivascular edema.  Development of cerebral edema and elevations in ICP may lead to increased cerebrovascular resistance and reduced cerebral blood flow.  ICP may be further elevated by increases in cerebral blood volume related to hypercarbia.  Impedance of drainage of the lumbar venous system secondary to the elevated intraabdominal pressure may decrease reabsorption of CSF and lead to a rise in ICP.
  • 18. PHYSIOLOGY OF ROBOTIC ASSISTED PELVIC SURGERY Intraocular Pressure Dynamics during steep Trendelenburg and Pneumoperitoneum Major determinants of IOP Aqueous humor flow Choroidal blood volume CVP Extraocular muscle tone Intraoperative hypertension, hypercarbia, position and elevation in CVP may lead to elevated IOP.
  • 20. 1.3% postop anemia 1% postop transfusion 3% corneal abrasion 6 % reoperation  Bleeding  Bowel injury  Hernia 0.2% PE
  • 21. ROBOTIC SYSTEM MALFUNCTION Review of 1,914 reports of da Vinci malfunction reported to FDA.  Instrument failures comprise the largest group. Arcing Fragmentation  Patient side cart malfunctions.  Console malfunction.  Endoscope malfunction.
  • 23. COMPLICATIONS OF PNEUMOPERITONEUM Subcutaneous Emphysema  Common ~5%.  Usually self limited.  Increases rate of CO2 uptake. Progressive mixed acidosis. o Continued postoperative absorption.  Further investigation Pneumothorax Capnothorax Pneumomediastinum
  • 24. COMPLICATIONS OF ACCESS Aortic injury. Robotically repaired. Journal of Endourology; 2011, Volume 25, Number 2, 235238
  • 25. INNOCENT BYSTANDER INJURY Iliac Vein hemorrhage. Bowel perforation. World Journal of Urology; Volume 26, Number 6, 595 602 Yonsei Medical Journal; 2011, Volume 52, Number 2, 365368
  • 26. CARDIOVASCULAR COMPLICATIONS Myocardial Infarction  Patient had preexisting coronary artery disease  Coronary stents insitu  Taken off antiplatelet, drugs prior to surgery, Congestive heart failure, refractory hypertension.
  • 27. CARDIOVASCULAR COMPLICATIONS Cardiac Arrest  Robotic arm pressed against patients neck Vagal nerve mediated response; bradycardia, nodal, atrioventricular dissociation, asystole. Catecholamine mediated response; sinus tach, ventricular extrasystole.
  • 28. PULMONARY COMPLICATIONS Pulmonary Edema  IAP raised from 15 to 20 mm Hg  30 degree Trendelenburg  CVP 31 cm H2O  Compression of lung  Absorption of crystalloid irrigating fluid Barotrauma, atelectasis, pneumothorax, capnothorax.
  • 29. NEUROMUSCULAR COMPLICATIONS Compartment Syndrome  LithotomyTrendelenburg  Surgery over 4.5 hours  Muscular calf muscles  Blood loss  Hypotension  Vasoactive drugs  Fibrate monotherapy  Elevated BMI
  • 30. CNS COMPLICATIONS Paradoxical Cerebral Air Embolism  45 degree Trendelenburg  CVP 816
  • 32. PREOPERATIVE History and Physical Exam  General Medical Assessment.  Patient specific factors which may be of concern with prolonged pneumoperitoneum or extremes of positioning.  Patient specific factors which may contribute to a difficult procedure.  Testing, blood work and consent driven by standard process.
  • 33.  Nervous system evaluation  CVA  Aneurysm  Elevated ICP Hydrocephalus, VP shunt Head trauma  Ocular pathology Glaucoma  Preexisting neuropathy or susceptibilities Diabetes, chemotherapy, peripheral vascular disease Extremes of body size, surgery lasting > 3 hours.
  • 34.  Cardiovascular Evaluation  Cardiomyopathy  CAD or MI by history or symptoms Angina Untreated obstructive coronary disease  Cardiac murmurs Evaluated by Echo Moderate or severe regurgitant valvular lesions  Peripheral vascular disease
  • 35.  Pulmonary Evaluation  COPD  Bullous emphysema  Spontaneous pneumothorax  Reactive airway disease  Prolonged pneumoperitoneum is contraindicated in moderate to severe disease states.
  • 36.  Renal disease  Renal insufficiency may benefit from protective strategies.  Renal failure Contraindication to prolonged pneumoperitoneum.
  • 37.  Lithotomy and Trendelenburg positioning  For every one hour spent in lithotomy, risk of nerve injury increases 100 fold.  Risks of compartment syndrome Myopathy, Fibrates or statin use, Muscular calf, PVD.  Lateral decubitus positioning  Cervical spine disease  Back pain, radiculopathy
  • 38.  Age  Increased risk of post operative ventilation (> 65 years old)  Increased risk of ICU admission  Obesity  Correlated with longer operative times.  Higher ventilatory pressures and risk of barotrauma.  Lower intraoperative oxygenation.  Associated with OSA, airway difficulty, diabetes.  Diaphragmatic hernia  Coagulopathy
  • 39.  Patient specific factors making for a difficult operation.  Morbid obesity  Adhesions  Prior surgery  Prior infection  Prior radiation  Procedure specific
  • 40. PREOPERATIVE  stop all antiplatelet medications for 1 week and ASA in radical prostatectomies  1 day before surgery should adhere to clear liquid diet.  Night before use laxative suppositories.  Bowel prep not used.  NPO at midnight.  Psychological preparation  Should be aware of plan for early discharge.  Informed of known side effects and complications which are within the realm of normal and do not affect recovery or discharge.
  • 41. PREOPERATIVE  Blood Type and Antibody Screen.  Peripheral IV access x 2.  Premedication for multimodal analgesia.  Antibiotic order.  Antigastric prophylaxis with Ranitidine and sodium citrate.
  • 42. CONDUCT OF ANESTHESIA  Monitors  Standard ASA monitors.  Orbicularis oculi twitch response is most similar to the adductor pollicis in onset and duration.
  • 43. CONDUCT OF ANESTHESIA  Monitors for special circumstances  Invasive monitors are indicated with inexperienced robotic programs or while a surgeon is inexperienced with a particular procedure.  Arterial blood pressure monitoring is indicated for patients with cardiac or pulmonary disease, with all cystectomy or nephrectomy operations and procedures planned for greater than four hours.  Central line placement for the purpose of resuscitative drug administration warrant re- consideration if robotic surgery is the appropriate approach.
  • 44. CONDUCT OF ANESTHESIA  Monitors for special circumstances  Cardiac output monitoring is indicated in cardiomyopathy. Esophageal doppler has been advocated by several authors.  TransEsophageal Echocardiography is the most advantageous monitor to add in the event of unexpected hemodynamic collapse.
  • 45. CONDUCT OF ANESTHESIA  Induction  Intubation  Avoid hemodynamic response to laryngoscopy.  Note the depth of ETT relative to the carina.  Ensure endotracheal tube is well secured.
  • 46. CONDUCT OF ANESTHESIA  General Endotracheal Anesthesia  Secure airway.  Controlled mechanical ventilation to properly handle carbon dioxide absorbed through pneumoperitoneum.  Continuous neuromuscular blockade until robot is undocked.  Nitrous oxide +/.  Low dose opiod.  Neuraxial techniques not currently recommended.  Thoracic epidural is associated with earlier return of bowel function and of benefit in cystectomy with ileal conduit.
  • 47. Once the robot is docked there is no further repositioning of the patient or bed without undocking the robot. Care must be taken the patient is positioned well enough to tolerate up to 9 hours in the final position.
  • 48. POSITIONING Sequence for Lithotomy –Steep Trendelenburg positioning  Awake tucking of arms.  Induction and intubation.  Eyes padded. Tegaderm applied.  Orogastric tube passed and gut decompressed.  Ensure face will be clear of equipment;  protective padding placed if necessary.  Fingers protected from bed hinges.  Legs raised simultaneously to bilateral stirrups.  Apply nerve stimulator.  Apply the bean bag ensuring no pressure points created.  Test the security of patient to bed in steep TrP.  Visualize face at all times.
  • 49. INTRAOPERATIVE MANAGEMENT  Ventilation  A fall in compliance will complicate ventilation in TrP.  Pressure Control Ventilation is recommended.  PEEP [5 cm H2O] is recommended.  Mild hyperventilation to avoid development of hypercarbia and resultant metabolic and respiratory acidemia.  Suggested minute ventilation is 1215 L/min.  Alternatively use twice the prePPN minute ventilation.  All changes in minute ventilation should be made through manipulation of respiratory rate, not tidal volume.  ETCO2 should plateau by 1520 min.  Appropriate to correlate to ABG in at risk patients.  Anticipate endobronchial intubation or mechanical obstruction in PPN.
  • 50. INTRAOPERATIVE MANAGEMENT  Perfusion  Patients at risk of cardiomyopathy may benefit from arteriovasodilators  ie nicardipine  Patients at risk of demand ischemia may benefit from alpha 2 agonist  ie clonidine or dexmeditomidine  Patients at risk of elevated intracranial pressure should be protected  mannitol, fluid restriction, normocapnia.  Patients at risk of renal insufficiency should be protected  Mannitol, nicardipine infusion, warm insufflation.  Patients at risk of compartment syndrome should have calves checked for tissue tugor and consider repositioning legs every two hours.
  • 51. INTRAOPERATIVE MANAGEMENT  Neuromuscular blockade  Absolute requirement for paralysis during period which the robot is docked to the patient.  Use of continuous infusion has been advocated.  Monitoring of neuromuscular function by train of four has been recommended.
  • 52. INTRAOPERATIVE MANAGEMENT  Temperature management  Over the body forced air warmer above the xiphoid  Isothermic carbon dioxide
  • 53. INTRAOPERATIVE MANAGEMENT  Fluid Management  Excess fluid administration in steep TrP can lead to facial edema with associated swelling of conjunctiva and/or airway. In prostatectomy, fluid restriction is warranted with a goal of less than 1 liter IVF up to the completion of the urethrovesical anastamosis. After the urethrovesical anastamosis is complete, liberalize fluid administration with the goal of an additional 1 liter IVF by the end of surgery.  Always discuss concerns regarding fluid status with surgeon.  Have a lower than usual threshold for colloid administration.
  • 54. INTRAOPERATIVE MANAGEMENT  Other intraoperative issues.  Thromboprophylaxis Elevation of the legs and placement to stirrups raises the risk of DVT formation. Intermittent Compression Devices lower DVT risk and promote venous return to the heart even with elevated intraabdominal pressure. Preoperative SQ Heparin is standard practice
  • 55. INTRAOPERATIVE MANAGEMENT  Other intraoperative issues.  Oral, facial and ocular burns have been associated with regurgitation of stomach acid in TrP. Orogastric decompression H2 blockade Carefully cover the eyes with Tegaderm.  Antiemetic prophylaxis.  Surgical Local Anesthetic Trocar / port site infiltration 5 – 10 mL Intraperitoneal installation 40 mL  Irrigation fluid and urine commonly overwhelm blood in the suction canisters making estimating blood loss difficult.
  • 56. PNEUMOPERITONEUM Recommendations state “to use the lowest IAP allowing adequate exposure … to avoid more than 12 mm Hg combined with Trendelenburg positioning because it reduces pulmonary compliance … and worsens ventilationperfusion impairment.”  Low pressure 57 mm Hg  Splanchnic perfusion preserved.  Normal 12 mm Hg  High 1520 mm Hg;  may be enacted to tamponade venous bleeding.  Anticipate bradycardia [asystole] with raising pneumoperitoneum and initial placement of ports.  Reassess for bilateral breath sounds to exclude endobronchial intubation.
  • 57. EMERGENCY PLANNING  Have a low threshold for advanced monitoring and arterial blood gas analysis.  Cardiovascular instability warrants immediate termination of PPN and TrP and, if refractory, investigation with transesophageal echo.  Advocate for aborting or suspending robotic technique if signs indicate patient is not tolerating steep TrP.  Have a plan for management of massive hemorrhage.  Be prepared to emergently undock robot.  It is acceptable to cardiovert with the robot docked.
  • 58. PREPARING FOR EMERGENCE  Terminate neuromuscular blocker administration once the robot is undocked.  Use “sigh” breath or recruitment maneuvers to reverse interval atelectasis from PPN or endobronchial intubation.  Elevate the patient’s head as soon as is permissible.  Maintain mechanical ventilation and hyperventilation until the patient awakens.
  • 59. EXTUBATION Anticipate a delay in awakening.  Elevate the head of bed.  Assess for subcutaneous emphysema.  Assess for head and neck swelling, and scleral and periorbital edema.  Perform endotracheal tube cuff “leak test”.  Ensure patient is following commands.  Auscultate for clear, bilateral breath sounds.  Ensure return of neuromuscular function.  If in any doubt of appropriate wakefulness, adequacy of ventilation, or ability to maintain a patent airway - do not extubate.
  • 60. POSTOPERATIVE  Standard monitors for recovery of general anesthesia.  Maintain elevation of the head of bed.  Hemoglobin analysis is indicated.  Blood gas analysis is indicated in the presence of hypoxia, delirium, hyperventilation or as follow up to intraoperative ABG abnormality.  Chest radiographs are indicated when significant subcutaneous emphysema is present, or if there are signs suggesting pneumothorax, or unexplained low oxygen saturations.
  • 61. POSTOPERATIVE  Patients should require little additional narcotic.  Reported pain should be evaluated as consistent with procedure, referred from phrenic nerve irritation, or related to intraoperative positioning.  Moderate or severe pain should prompt evaluation by surgeon.  Mental status should be evaluated to rule out hypercarbia, elevated intracranial pressure and stroke.  Positional neuropathies if any, need to be looked into.  Oliguria should be promptly treated with 500 mL bolus of crystalloid and then continue at150 mL/Hr.
  • 62. Chief Concerns for Anesthesia during Robotic Assisted Surgery  Limitation of access.  Inexperience of surgeon, assistants or team.  Extremes of patient positioning.  Length of case.  Hypothermia.  Respiratory and hemodynamic effects of pneumoperitoneum and extremes of positioning.  Occult blood loss.  Unsuspected visceral injury.