liquid dosage form syrup

1. PRESENTED BY:
L.GOPI B.Pharm.,
AADHI BHAGAWAN COLLEGE OF PHARMACY
RANTHAM
GUIDED BY:
K.Shyamala M.Pharm.,
PROF OF DEPARTMENT OF PHARMACEUTICS
AADHI BHAGAWAN COLLEGE OF PHARMACY
RANTHAM

2. SYRUP
It’s a liquid dosage form taken to the oral route.
Viscous , concentrated solution of sucrose and
other sugars.
With ( or ) with out medicaments.
Flavouring agent vehicle.
Contain up to 85% to resist bacterial growth.
Intended for oral use.

3. COMPONENTS
Sucrose ( or ) other substitute ( glycogenic
or non-glycogenic )
Glycogenic = sorbitol , glycerine , propyl
glycol.
Non – glycogenic = methyl cellulose ,
Hydroxy methyl cellulose ( suitable for
diapetic partients )

4. COLOURING AGENTS
 Green = Mint
 Brown = Chocolate
 Red = Amaranth

7. DISADVANDAGES :
• Formation of invert sugar.
• Effect the taste , stability.
• glucose + fructose
sucrose
hydrolysis heat
invert sugar form

8. CARAMELIZATION :
• The product become black color is sucrose is over heat is called as
caramelization.
• The process avoid maintain temperature.
sugar = 110˚C
galatose = 160˚C
glucose = 160˚C
maltose = 180˚C
saccharose = 160˚C

14. MEDICATED SYRUP CONTAINING A
THERAPEUTIC AGENTS
1. Demerol syrup
2. Thorazine syrup
3. Phenergan syrup
4. Lithium citrate syrup
5. Gualfenesin syrup
6. Lpecal syrup

16. Example for other syrup image:

17. CONTAINERS

18. TYPES OF CONTAINERS :
1. Plastic container = colorless , brown color container mostly use
other color is available
2. Glass container = colorless , brown color form

19. TYPES OF CORKS :

20. STORAGE:
 It’s maintain the temperature.
 stable temperature.
 completely fill the container .
 no more air phase in surface of
product growth of micro organism.
 so completely fill the container

21.  so not completely fill the container to form microbial
organism growth.

25. THANK YOU

26. PREPARED BY :
L.GOPI B.Pharm., THIRD YEAR
CREATER 6 PHARMA GROUP
2012 – 2016
ABCP