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Silencing Inhibitor of Cell Replication Spurs
Insulin-Producing Beta Cells to Reproduce AND
Small Molecule Shows Promise as Anti-Cancer
Therapy

Biology Folding
Teacher: Lina Martínez
Jorge Luis Ferreira Morales
Medicine Student
III Semestrer
2014
UPB
•

Modifying the DNA of mutant and normal cells
is the new pathway which is leading all
investigations, and this offers the possibility to
predict the functions of a living cell and avoid
non wished facts.

•

New alternatives of treatment are being
discovered now, but the goal is to cure some
diseases knowing their weak points and in this
way, avoid deaths and extend this gorgeous
life.

•

Diabetes and Cancer are very important
diseases and these two news bring us some
findings about them.
Jan 16, 2014
SILENCING INHIBITOR OF CELL REPLICATION SPURS
INSULIN-PRODUCING BETA CELLS TO REPRODUCE

In this study, human pancreatic
beta cells were transplanted in a
mouse model, and they
replicated showing normal
functions.

Diabetes type I Ior IIIIimplicate
Diabetes type or implicate
destruction or less amount of
destruction or less amount of
pancreatic beta cells
pancreatic beta cells
So
Restoration of beta-cell
Restoration of beta-cell
mass can reverse or
mass can reverse or
ameliorate both forms of
ameliorate both forms of
diabetes.
diabetes.
SILENCING INHIBITOR OF CELL REPLICATION SPURS
INSULIN-PRODUCING BETA CELLS TO REPRODUCE
SILENCING INHIBITOR OF CELL REPLICATION SPURS
INSULIN-PRODUCING BETA CELLS TO REPRODUCE
In the future, suppressing genes
like p57 could lead the whole
world to better treatments.
This experiment shows that
investigations are being runned
out everywhere and researchers
are very foccussed on important
diseases with high prevalence in
the society.
Preventing or even cure a
pathology is an incredible
capacity of progress.
Jan 13 2014
In this study, Johns Hopkins scientists
focused on the ability of BMH-21 to
sabotage the transcription pathway
RNA Polymerase pathway, preventing
replication and communication of
cancer cells.

Transcription pathways are the
Transcription pathways are the
means by which certain proteins
means by which certain proteins
that direct cell division are put
that direct cell division are put
into action by cells.
into action by cells.

Cancer without this
Cancer without this
transcription proccess can’t
transcription proccess can’t
function
function
Every intend of discovering a way to
fight against this tumors is a step
more to get to prevent and offer a
treatment for thousands of people
who become devastated when
they realized what they have is
cancer.
It’s sad to see how this illness takes a
lot of lives and finding a drug like
BMH-21 is really inspiring and
promising to the future of defeating
Cancer
•

Perelman School of Medicine at the University of
Pennsylvania. (2014, January 16). Silencing inhibitor of cell
replication spurs insulin-producing beta cells to reproduce.
ScienceDaily. Retrieved February 14, 2014 from
www.sciencedaily.com/releases/2014/01/140116162107.htm

•

Johns Hopkins Medicine. (2014, January 13). Small molecule
shows promise as anti-cancer therapy. ScienceDaily.
Retrieved February 14, 2014 from
www.sciencedaily.com/releases/2014/01/140113152629.htm
biology folding. anticancer and antidiabetes

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biology folding. anticancer and antidiabetes

  • 1. Silencing Inhibitor of Cell Replication Spurs Insulin-Producing Beta Cells to Reproduce AND Small Molecule Shows Promise as Anti-Cancer Therapy Biology Folding Teacher: Lina Martínez Jorge Luis Ferreira Morales Medicine Student III Semestrer 2014 UPB
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  • 4. • Modifying the DNA of mutant and normal cells is the new pathway which is leading all investigations, and this offers the possibility to predict the functions of a living cell and avoid non wished facts. • New alternatives of treatment are being discovered now, but the goal is to cure some diseases knowing their weak points and in this way, avoid deaths and extend this gorgeous life. • Diabetes and Cancer are very important diseases and these two news bring us some findings about them.
  • 6. SILENCING INHIBITOR OF CELL REPLICATION SPURS INSULIN-PRODUCING BETA CELLS TO REPRODUCE In this study, human pancreatic beta cells were transplanted in a mouse model, and they replicated showing normal functions. Diabetes type I Ior IIIIimplicate Diabetes type or implicate destruction or less amount of destruction or less amount of pancreatic beta cells pancreatic beta cells So Restoration of beta-cell Restoration of beta-cell mass can reverse or mass can reverse or ameliorate both forms of ameliorate both forms of diabetes. diabetes.
  • 7. SILENCING INHIBITOR OF CELL REPLICATION SPURS INSULIN-PRODUCING BETA CELLS TO REPRODUCE
  • 8. SILENCING INHIBITOR OF CELL REPLICATION SPURS INSULIN-PRODUCING BETA CELLS TO REPRODUCE
  • 9. In the future, suppressing genes like p57 could lead the whole world to better treatments. This experiment shows that investigations are being runned out everywhere and researchers are very foccussed on important diseases with high prevalence in the society. Preventing or even cure a pathology is an incredible capacity of progress.
  • 11. In this study, Johns Hopkins scientists focused on the ability of BMH-21 to sabotage the transcription pathway RNA Polymerase pathway, preventing replication and communication of cancer cells. Transcription pathways are the Transcription pathways are the means by which certain proteins means by which certain proteins that direct cell division are put that direct cell division are put into action by cells. into action by cells. Cancer without this Cancer without this transcription proccess can’t transcription proccess can’t function function
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  • 14. Every intend of discovering a way to fight against this tumors is a step more to get to prevent and offer a treatment for thousands of people who become devastated when they realized what they have is cancer. It’s sad to see how this illness takes a lot of lives and finding a drug like BMH-21 is really inspiring and promising to the future of defeating Cancer
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  • 19. • Perelman School of Medicine at the University of Pennsylvania. (2014, January 16). Silencing inhibitor of cell replication spurs insulin-producing beta cells to reproduce. ScienceDaily. Retrieved February 14, 2014 from www.sciencedaily.com/releases/2014/01/140116162107.htm • Johns Hopkins Medicine. (2014, January 13). Small molecule shows promise as anti-cancer therapy. ScienceDaily. Retrieved February 14, 2014 from www.sciencedaily.com/releases/2014/01/140113152629.htm