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Social Isolation, Frailty and Health outcomes in Community-
Dwelling Older Adults: A Scoping Review
Fereshteh Mehrabi 1,2, François Béland 1,2,3
1 School of Public Health (ESPUM), University of Montreal
2 Research Institute of Public Health of the University of Montreal (IRSPUM)
3 SOLIDAGE the McGill University-University of Montreal Research Group on Frailty and Aging
Direction des affaires internationales
Objective
1
To identify the relationship
between social isolation,
frailty and health
outcomes in community
dwelling older adults
Social Isolation
Objective Subjective
50% of older
adults are isolated
Quantity of relationships Quality of relationships
Berkman and Kirshna 2014
2
Social Networks Social Participation Social Support Loneliness
Frailty is defined as a state of increased vulnerability resulting from age-associated
decline in reserve and function across multiple physiological systems which leads to
poor health outcomes.
Physical Frailty
disability
comorbidityFrailty
Fried et al., 2001
Frailty
Slowness
Weight
loss
Exhaustion
Low
physical
activity
Weakness
3
The relationships between social isolation, frailty and health based
on three models
Model 1
Health
Outcomes
Social
Isolation
Frailty
Model 2a
Mediation
Social
Isolation
Health
Outcomes
Frailty
Social
Isolation
Health
OutcomesFrailty
Model 2b
Mediation
4
Social
Isolation
Social
Isolation
Health
Outcomes
Health
Outcomes
Frailty
FrailtyModel 3a
Moderation
Model 3b
Moderation
The relationships between social isolation, frailty and health based on
three models
5
Arksey & O‘Malley’s Methodological Framework
1
Research
Questions
2
Relevant
Studies
3
Select
Studies
4
Chart Data
5
Collate,
Summarize
Report
What evidence exists in the relationship
between social isolation and frailty?
What evidence exists in the relationship
between social isolation, frailty, and
their health outcomes?
What are the limitations and
gaps in the literature?
1
2
3
6
Flowchart of Scoping Review
MEDLINE 785
EMBASE1136
CINAHL 567
Web of Science 547
Scopus 674
PsycInfo 292
Assessed for eligibility:
57
33 articles excluded
Reasons:
N=23 (no frailty measures or
results)
N=8 (no social isolation
measures or results)
N= 2 ( review articles)
Studies meeting the
inclusion criteria:
25
Electronic
search: 4001
studies
Duplicates: 2113
Screened &
excluded: 1888
Inclusion criteria:
1. Community-dwelling older
adults aged 60 years +
2. Measuring social isolation
3. Measuring physical frailty
4. Articles in English and French1 2
3 4 5
From 2001 to June 2018
additional
Articles:3 7
Results
Characteristics of included studies
8
56%
(N=14)28%
(N=7)
8%
N=2
4%
N=1
4%
N=1
Europe South and East Asia US Australia Brazil
4 5
3
5
5
4
1
4
0
2
4
6
8
10
12
14
16
18
Social Networks Social Support Social Participation Social Isolation Loneliness
Social isolation associated with frailty status
No evidence of association Significant association
1- Results: Social isolation and frailty
9
Interaction effect
Social
support
Stressors
Frailty
Social
isolation
chronic disease &
physiological
reserve decline
Frailty
Moderation and Mediation
1- Results: Social isolation and frailty
10
2- Results: Social Isolation, Frailty and Health Outcomes
3 4
10
9
4
0
2
4
6
8
10
12
Frailty & health Social isolation & health Social isolation & frailty
The association between social isolation, frailty and health
No evidence of association Significant association
Health outcomes:
- Falls
- Disability
- Mortality
- Cognitive decline
- Discharge to the
higher level of care
11
2- Results: Social Isolation, Frailty and Health Outcomes
Social
support
Discharge to
a higher
level of care
Frailty
Functional
decline &
mortality
Social
participation
Frailty
No evidence of interaction effect Evidence of interaction effect
12
3- Gaps: Moderation, Mediation or Interaction Effect
Social isolation Frailty
Moderation effect No study identified No study identified
Mediation effect No study identified No study identified
Interaction effect 2 studies:
Social support & frailty
social participation & frailty
No study identified
Social
Isolation
Health
Outcomes
Frailty
Social
Isolation
Health
OutcomesFrailty
13
?
?
? ?
?
?
3-Limitations and Gaps in included studies
§ Presence of gender inequality ( in 2 Taiwanese studies)
§ Subjective aspect of social isolation or loneliness
o (Social Isolation & Frailty: 4 out of 18)
o(Social Isolation & Frailty & Health: 1 out of 8)
§ Absence of health outcomes: life satisfaction, quality of life,
depression, dementia
Cross-sectional Longitudinalvs
14
Social Networks Social Participation Social Support Loneliness
Discussion and conclusion
15
Objective Subjective
Comprising both objective and
subjective aspects of social
isolation
Discussion and conclusion
üPossible role of frailty as a moderator and mediator on the relationship between social isolation
and health
üPossible role of social isolation as a moderator and mediator on the relationship between frailty
and health
16
Social
Isolation
Health
Outcomes
Frailty
Social
Isolation
Health
OutcomesFrailty
Thank you
17
Direction des affaires internationales
fereshteh.mehrabi@umontreal.ca
@FereshteMehrabi
The comic of my research which is available in my twitter and FAÉCUM’s
Facebook:
Selected References
• Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, Seeman T, Tracy R, Kop
WJ, Burke G: Frailty in older adults: evidence for a phenotype. The Journals of Gerontology
Series A: Biological Sciences and Medical Sciences 2001, 56(3):M146-M157
• Berkman LF, Krishna A: Social Network Epidemiology. In: Social Epidemiology. Edited by
Berkman LF, Kawachi I, Glymour MM, 2 edn: Oxford University Press; 2014: 234-289
• Images:
• https://theinnovativeeducator.blogspot.com/2010/04/death-of-freemiums-at-ning-could-mean.html
• https://www.vectorstock.com/royalty-free-vectors/sad-depressed-broken-lonely-vectors
• https://clipground.com/image-post/28338-collaboration-clipart-
14.jpg.html#overlayGallery_post_28338_collaboration-clipart-14.jpg
• https://dumielauxepices.net/sites/default/files/drawn-broken-heart-lonely-516739-6369655.jpg
18

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Iuhpe presentation: Fereshteh Mehrabi

  • 1. Social Isolation, Frailty and Health outcomes in Community- Dwelling Older Adults: A Scoping Review Fereshteh Mehrabi 1,2, François Béland 1,2,3 1 School of Public Health (ESPUM), University of Montreal 2 Research Institute of Public Health of the University of Montreal (IRSPUM) 3 SOLIDAGE the McGill University-University of Montreal Research Group on Frailty and Aging Direction des affaires internationales
  • 2. Objective 1 To identify the relationship between social isolation, frailty and health outcomes in community dwelling older adults
  • 3. Social Isolation Objective Subjective 50% of older adults are isolated Quantity of relationships Quality of relationships Berkman and Kirshna 2014 2 Social Networks Social Participation Social Support Loneliness
  • 4. Frailty is defined as a state of increased vulnerability resulting from age-associated decline in reserve and function across multiple physiological systems which leads to poor health outcomes. Physical Frailty disability comorbidityFrailty Fried et al., 2001 Frailty Slowness Weight loss Exhaustion Low physical activity Weakness 3
  • 5. The relationships between social isolation, frailty and health based on three models Model 1 Health Outcomes Social Isolation Frailty Model 2a Mediation Social Isolation Health Outcomes Frailty Social Isolation Health OutcomesFrailty Model 2b Mediation 4
  • 6. Social Isolation Social Isolation Health Outcomes Health Outcomes Frailty FrailtyModel 3a Moderation Model 3b Moderation The relationships between social isolation, frailty and health based on three models 5
  • 7. Arksey & O‘Malley’s Methodological Framework 1 Research Questions 2 Relevant Studies 3 Select Studies 4 Chart Data 5 Collate, Summarize Report What evidence exists in the relationship between social isolation and frailty? What evidence exists in the relationship between social isolation, frailty, and their health outcomes? What are the limitations and gaps in the literature? 1 2 3 6
  • 8. Flowchart of Scoping Review MEDLINE 785 EMBASE1136 CINAHL 567 Web of Science 547 Scopus 674 PsycInfo 292 Assessed for eligibility: 57 33 articles excluded Reasons: N=23 (no frailty measures or results) N=8 (no social isolation measures or results) N= 2 ( review articles) Studies meeting the inclusion criteria: 25 Electronic search: 4001 studies Duplicates: 2113 Screened & excluded: 1888 Inclusion criteria: 1. Community-dwelling older adults aged 60 years + 2. Measuring social isolation 3. Measuring physical frailty 4. Articles in English and French1 2 3 4 5 From 2001 to June 2018 additional Articles:3 7
  • 9. Results Characteristics of included studies 8 56% (N=14)28% (N=7) 8% N=2 4% N=1 4% N=1 Europe South and East Asia US Australia Brazil
  • 10. 4 5 3 5 5 4 1 4 0 2 4 6 8 10 12 14 16 18 Social Networks Social Support Social Participation Social Isolation Loneliness Social isolation associated with frailty status No evidence of association Significant association 1- Results: Social isolation and frailty 9
  • 11. Interaction effect Social support Stressors Frailty Social isolation chronic disease & physiological reserve decline Frailty Moderation and Mediation 1- Results: Social isolation and frailty 10
  • 12. 2- Results: Social Isolation, Frailty and Health Outcomes 3 4 10 9 4 0 2 4 6 8 10 12 Frailty & health Social isolation & health Social isolation & frailty The association between social isolation, frailty and health No evidence of association Significant association Health outcomes: - Falls - Disability - Mortality - Cognitive decline - Discharge to the higher level of care 11
  • 13. 2- Results: Social Isolation, Frailty and Health Outcomes Social support Discharge to a higher level of care Frailty Functional decline & mortality Social participation Frailty No evidence of interaction effect Evidence of interaction effect 12
  • 14. 3- Gaps: Moderation, Mediation or Interaction Effect Social isolation Frailty Moderation effect No study identified No study identified Mediation effect No study identified No study identified Interaction effect 2 studies: Social support & frailty social participation & frailty No study identified Social Isolation Health Outcomes Frailty Social Isolation Health OutcomesFrailty 13 ? ? ? ? ? ?
  • 15. 3-Limitations and Gaps in included studies § Presence of gender inequality ( in 2 Taiwanese studies) § Subjective aspect of social isolation or loneliness o (Social Isolation & Frailty: 4 out of 18) o(Social Isolation & Frailty & Health: 1 out of 8) § Absence of health outcomes: life satisfaction, quality of life, depression, dementia Cross-sectional Longitudinalvs 14
  • 16. Social Networks Social Participation Social Support Loneliness Discussion and conclusion 15 Objective Subjective Comprising both objective and subjective aspects of social isolation
  • 17. Discussion and conclusion üPossible role of frailty as a moderator and mediator on the relationship between social isolation and health üPossible role of social isolation as a moderator and mediator on the relationship between frailty and health 16 Social Isolation Health Outcomes Frailty Social Isolation Health OutcomesFrailty
  • 18. Thank you 17 Direction des affaires internationales fereshteh.mehrabi@umontreal.ca @FereshteMehrabi The comic of my research which is available in my twitter and FAÉCUM’s Facebook:
  • 19. Selected References • Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, Seeman T, Tracy R, Kop WJ, Burke G: Frailty in older adults: evidence for a phenotype. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2001, 56(3):M146-M157 • Berkman LF, Krishna A: Social Network Epidemiology. In: Social Epidemiology. Edited by Berkman LF, Kawachi I, Glymour MM, 2 edn: Oxford University Press; 2014: 234-289 • Images: • https://theinnovativeeducator.blogspot.com/2010/04/death-of-freemiums-at-ning-could-mean.html • https://www.vectorstock.com/royalty-free-vectors/sad-depressed-broken-lonely-vectors • https://clipground.com/image-post/28338-collaboration-clipart- 14.jpg.html#overlayGallery_post_28338_collaboration-clipart-14.jpg • https://dumielauxepices.net/sites/default/files/drawn-broken-heart-lonely-516739-6369655.jpg 18