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BRIDGING THE GAP BETWEEN
OPHTHALMOLOGISTS &
PEDIATRICIANS
By: Othman Al-Abbadi, M.D
Supervisor: Dema Otoum, M.D
VISUAL MILESTONES
Birth
Poor eyesight
Blink in response to bright light
or touching eye
Eyes are sometimes
uncoordinated, may look
crossed-eyed
1 month
looks at faces and pictures with
contrasting black and white
images
Can follow an object up to 90
degrees
Watches parent closely
Tears begin to work
2-3 months
Looks at hands
Follows light, faces, and objects
 It's normal for a newborn's eyes to wander or
cross occasionally during the first few months
of life.
 By the time baby is 4 to 6 months old, the eyes
usually straighten out.
 If one or both eyes continue to wander in, out, up,
or down - even intermittently -it's probably due
to strabismus.
4-5 months
Beginning to reach hands to
objects
Can stare at block
Will look at self in mirror
Will look at own hand
5-7 months
Has full color vision
Able to see at longer distances
Can pick up a toy that is
dropped
Will turn head to see an object
Likes certain colors
Will touch image of self in mirror
7-11 months
Can stare at small objects
Begins to have depth perception
Plays peek-a-boo
11-12 months
Can watch objects that are
moving fast
12-14 months
Able to place shapes in proper
holes
Becomes interested in pictures
Recognizes familiar objects and
pictures in books, may point to
some objects when asked,
"Where is the ...?"
Points and gestures for objects
and actions
18-24 months
Able to focus on objects near and
far
Can point to body parts (nose,
hair, and eyes) when asked
NASOLACRIMAL DUCT
OBSTRUCTION
 Tears normally drain through small openings in
the medial part of the upper and lower eyelids
called puncta and enter the nose through the
nasolacrimal duct.
 Tear duct obstruction prevents tears from
draining through this system normally. 
 If the tear duct is blocked, there will be backflow
of tears and discharge from the eye
• Congenital NLD obstruction results from
incomplete canalization of the NLD.
• Symptoms gets aggravated by nasal infection,
discharge, or any mass occupying pathology
blocking the opening of the NLD.
• Epiphora affects at least 20% of neonates, but
spontaneous resolution occurs in over 95% within
the first year; it has been suggested that early
epiphora with resolution may be regarded as a
normal variant.
SIGNS
• Epiphora and matting of eyelashes
– constant or intermittent,
– may be particularly noticeable when the child has an
upper respiratory tract infection.
• Gentle pressure over the lacrimal sac may cause
mucopurulent reflux.
• Acute dacryocystitis is very rare.
• The fluorescein disappearance test is highly
specific in this setting.
DIFFERENTIAL DIAGNOSES
 Punctal atresia,
 Congenital glaucoma,
 Chronic conjunctivitis (e.g. chlamydial),
 Keratitis,
 Uveitis.
MANAGEMENT
 Refer to ophthalmologist
LACRIMAL SAC MASSAGE
 Massage of the lacrimal sac has been suggested
as a means of rupturing a membranous
obstruction by hydrostatic pressure. The index
finger is initially placed over the common
canaliculus to block reflux, and then rolled over
the sac, massaging downwards.
PROBING
 Passage of a fine wire via the canalicular system
and nasolacrimal duct to disrupt the obstructive
membrane at the valve of Hasner.
 Usually regarded as the definitive treatment.
 Probing can be repeated if the first procedure is
unsuccessful.
 Can be combined with intubation of silastic tube.
CONGENITAL DACRYOCYSTOCOELE
 Collection of amniotic fluid or mucus in the
lacrimal sac caused by an imperforate Hasner
valve.
 It’s a complication of NLD obstruction.
 Present perinatally with a bluish cystic swelling at or
below the medial canthus accompanied by epiphora.
MANAGEMENT
 It may resolve with conservative treatment
 Risk of dacreocystitis is much higher than NLD
obstruction
 Usually needs probing & silastic tube implant.
CAPILLARY HEMANGIOMA
 The most common tumour of the orbit and
periorbital area in childhood
 5% of population
 Girls are affected more commonly than boys by
three folds.
 Strawberry birthmark
 Benign tumour
 Large or multiple lesions may have associated
visceral involvement, which can lead to serious
complications such as thrombocytopenia
(Kasabach– Merritt syndrome, with up to 50%
mortality) and high-output cardiac failure
 systemic investigation should be considered
PHACE SYNDROME
 Posterior fossa malformations
 Hemangiomas
 Arterial lesions
 Cardiac abnormalities
 Eye abnormalities
PRESENTATION
 30% present at birth
 The remainder within the first 6 months.
 Start to decrease in size after the first year
 30% resolve by the age of 3
 75% resolve by the age of 7
INDICATIONS FOR TREATMENT
 Refractive amblyopia
 Deprivation (occlusion) amblyopia
 Optic nerve compression
 Esxposure keratopathy
 Cosmesis
MANAGEMENT LINES
 Beta-blockers
 Steroid injection
 Laser
 Interferon alpha
 Local resection
VIGABATRIN
 Antiepileptic drug 
 Inhibits the breakdown of γ-aminobutyric
acid (GABA)
 structural analog of GABA but doesn’t bind to
GABA receptors
OCULAR SIDE EFFECTS
 Bilateral concentric, predominantly nasal visual
field constriction.
 Uncommon except at high cumulative dose.
 The threshold for its prescription is generally
high due to the ocular toxicity. The risk is higher
in males than females
PRESENTATION
 Months or years after starting treatment.
 Asymptomatic unless scotoma at or near fixation.
 Bilateral concentric or binasal visual field
defects.
 Optic atrophy, arteriolar narrowing, abnormal
macular reflexes and surface wrinkling can be
seen.
PROGNOSIS
 Changes persist even if treatment is stopped, but
sometimes do not progress if continued.
SCREENING
 A baseline visual assessment, including visual
fields and OCT, is recommended prior to starting
treatment and thereafter every 3 months.
 In young children and others unable to perform
field or OCT testing, the optimal monitoring
modality is undetermined
NEUROFIBROMATOSIS SCREENING
GUIDELINES
BRIDGING THE GAP BETWEEN OPHTHALMOLOGISTS & PEDIATRICIANS

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BRIDGING THE GAP BETWEEN OPHTHALMOLOGISTS & PEDIATRICIANS

  • 1. BRIDGING THE GAP BETWEEN OPHTHALMOLOGISTS & PEDIATRICIANS By: Othman Al-Abbadi, M.D Supervisor: Dema Otoum, M.D
  • 3. Birth Poor eyesight Blink in response to bright light or touching eye Eyes are sometimes uncoordinated, may look crossed-eyed 1 month looks at faces and pictures with contrasting black and white images Can follow an object up to 90 degrees Watches parent closely Tears begin to work 2-3 months Looks at hands Follows light, faces, and objects
  • 4.  It's normal for a newborn's eyes to wander or cross occasionally during the first few months of life.  By the time baby is 4 to 6 months old, the eyes usually straighten out.  If one or both eyes continue to wander in, out, up, or down - even intermittently -it's probably due to strabismus.
  • 5. 4-5 months Beginning to reach hands to objects Can stare at block Will look at self in mirror Will look at own hand 5-7 months Has full color vision Able to see at longer distances Can pick up a toy that is dropped Will turn head to see an object Likes certain colors Will touch image of self in mirror 7-11 months Can stare at small objects Begins to have depth perception Plays peek-a-boo 11-12 months Can watch objects that are moving fast
  • 6. 12-14 months Able to place shapes in proper holes Becomes interested in pictures Recognizes familiar objects and pictures in books, may point to some objects when asked, "Where is the ...?" Points and gestures for objects and actions 18-24 months Able to focus on objects near and far Can point to body parts (nose, hair, and eyes) when asked
  • 8.  Tears normally drain through small openings in the medial part of the upper and lower eyelids called puncta and enter the nose through the nasolacrimal duct.  Tear duct obstruction prevents tears from draining through this system normally.   If the tear duct is blocked, there will be backflow of tears and discharge from the eye
  • 9.
  • 10. • Congenital NLD obstruction results from incomplete canalization of the NLD. • Symptoms gets aggravated by nasal infection, discharge, or any mass occupying pathology blocking the opening of the NLD. • Epiphora affects at least 20% of neonates, but spontaneous resolution occurs in over 95% within the first year; it has been suggested that early epiphora with resolution may be regarded as a normal variant.
  • 11. SIGNS • Epiphora and matting of eyelashes – constant or intermittent, – may be particularly noticeable when the child has an upper respiratory tract infection. • Gentle pressure over the lacrimal sac may cause mucopurulent reflux. • Acute dacryocystitis is very rare. • The fluorescein disappearance test is highly specific in this setting.
  • 12.
  • 13. DIFFERENTIAL DIAGNOSES  Punctal atresia,  Congenital glaucoma,  Chronic conjunctivitis (e.g. chlamydial),  Keratitis,  Uveitis.
  • 14. MANAGEMENT  Refer to ophthalmologist
  • 15. LACRIMAL SAC MASSAGE  Massage of the lacrimal sac has been suggested as a means of rupturing a membranous obstruction by hydrostatic pressure. The index finger is initially placed over the common canaliculus to block reflux, and then rolled over the sac, massaging downwards.
  • 16.
  • 17. PROBING  Passage of a fine wire via the canalicular system and nasolacrimal duct to disrupt the obstructive membrane at the valve of Hasner.  Usually regarded as the definitive treatment.  Probing can be repeated if the first procedure is unsuccessful.  Can be combined with intubation of silastic tube.
  • 18.
  • 19. CONGENITAL DACRYOCYSTOCOELE  Collection of amniotic fluid or mucus in the lacrimal sac caused by an imperforate Hasner valve.  It’s a complication of NLD obstruction.
  • 20.
  • 21.  Present perinatally with a bluish cystic swelling at or below the medial canthus accompanied by epiphora.
  • 22. MANAGEMENT  It may resolve with conservative treatment  Risk of dacreocystitis is much higher than NLD obstruction  Usually needs probing & silastic tube implant.
  • 24.  The most common tumour of the orbit and periorbital area in childhood  5% of population  Girls are affected more commonly than boys by three folds.  Strawberry birthmark  Benign tumour
  • 25.  Large or multiple lesions may have associated visceral involvement, which can lead to serious complications such as thrombocytopenia (Kasabach– Merritt syndrome, with up to 50% mortality) and high-output cardiac failure  systemic investigation should be considered
  • 26. PHACE SYNDROME  Posterior fossa malformations  Hemangiomas  Arterial lesions  Cardiac abnormalities  Eye abnormalities
  • 27.
  • 28. PRESENTATION  30% present at birth  The remainder within the first 6 months.  Start to decrease in size after the first year  30% resolve by the age of 3  75% resolve by the age of 7
  • 29.
  • 30. INDICATIONS FOR TREATMENT  Refractive amblyopia  Deprivation (occlusion) amblyopia  Optic nerve compression  Esxposure keratopathy  Cosmesis
  • 31.
  • 32.
  • 33. MANAGEMENT LINES  Beta-blockers  Steroid injection  Laser  Interferon alpha  Local resection
  • 35.  Antiepileptic drug   Inhibits the breakdown of γ-aminobutyric acid (GABA)  structural analog of GABA but doesn’t bind to GABA receptors
  • 36. OCULAR SIDE EFFECTS  Bilateral concentric, predominantly nasal visual field constriction.  Uncommon except at high cumulative dose.  The threshold for its prescription is generally high due to the ocular toxicity. The risk is higher in males than females
  • 37. PRESENTATION  Months or years after starting treatment.  Asymptomatic unless scotoma at or near fixation.  Bilateral concentric or binasal visual field defects.  Optic atrophy, arteriolar narrowing, abnormal macular reflexes and surface wrinkling can be seen.
  • 38. PROGNOSIS  Changes persist even if treatment is stopped, but sometimes do not progress if continued.
  • 39. SCREENING  A baseline visual assessment, including visual fields and OCT, is recommended prior to starting treatment and thereafter every 3 months.  In young children and others unable to perform field or OCT testing, the optimal monitoring modality is undetermined