Lamin B1 is an intermediate filament protein that is a key structural component of the nuclear envelope. It maintains the stability and strength of cells by surrounding and supporting the nucleus. As part of the nuclear envelope, lamin B1 helps regulate molecular movement in and out of the nucleus and also plays a role in DNA replication and gene expression by organizing chromosomes.

1. Topic 1: Quick facts about LMNB1. Lamin B1 is known as intermediate filament protein.
They are structural protein which maintain stability and provide strength to cells. The
biochemical structure of nuclear Lamins consist of prominent 60 to 80 kDa proteins and
ultimately recognized as intermediate filament (IF) by proteins arrangements [1-6]. The name
intermediate filament refers to the average diameter of assembled intermediate fibers (10 to
12 nm), which is between that of actin microfilaments (7 to 10 nm) and that of microtubules
(25 nm)
Lamin B1 is a scaffolding (supporting) component of the nuclear envelope, which is the
structure that surrounds the nucleus in cells. As part of the nuclear envelope, lamin B1 helps
regulate the movement of molecules into and out of the nucleus. The protein also plays a role
in the copying (replication) of DNA in preparation for cell division and the activity
(expression) of many genes by being involved in the organization of chromosomes within the
nucleus.
Resource: https://medlineplus.gov/genetics/gene/lmnb1/#resources
Dittmer TA, Misteli T. 2011. The lamin protein family. Genome Biol 12:222-222.