Basic detail about inflammation

1. Krithiga K
Student ID: f7e51b14e
Academic Writing
UGC19 GE03

2. Basic understanding
 Living tissues have blood and nerve supply
 Usually end with suffix “itis” eg. Myocarditis, nephritis
etc

3. Inflammation-Definition
 Part of the complex biological response of vascular
tissue
 Protective response involving host cells, blood vessels,
proteins and other chemical mediators
Derived from Latin word “inflammo” which means “I
ignite, set alight”.
The cardinal signs of inflammation are apparent in acute
inflammatory response

4. Five cardinal signs- Celsius and
Galen
• Calor- Heat
• Rubor-Redness
• Tumor- Swelling
• Dolor- Pain
• Functio laesa- Loss of function

5. Reasons for cardinal signs
Vascular changes
Capillary permeability
Resulting in exudation
Tumour-Swelling
Tumour and Dolor
result in loss of
function –Functio
laesa
Dolor-Pressure on
nerve endings
Vasodilatation
Rubor-Redness
Calor-Heat

6. Reasons for cardinal signs
Calor
Rubor
• Increased blood
supply
Tumor
• Accumulation of
fluid
Dolor
• Chemical
mediators and
pressure exerted
on nerve endings
Functio
laesa
•Multiple causes
Inflammation

7. Acknowledgment
 Course on “Academic Writing” by Dr. Ajay Semalty