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URINARY SYSTEM
Dr Wairimu Mwaura
REVIEW QUESTIONS
1.List five functions of the respiratory system. (5
marks)
2.Which of the following parts of the respiratory
system produces sound for speech?
a.Oropharynx
b.Nasal cavity
c.Larynx
d.Trachea
OBJECTIVES
◦Organs of the urinary system
◦Functions of the urinary system
◦Kidney- parts and functions
◦Ureters
◦Urinary bladder
◦Urethra
ORGANS OF THE URINARY SYSTEM
◦2 Kidneys
◦2 Ureters
◦Bladder
◦Urethra
ORGANS OF THE URINARY SYSTEM
Primary organ is the kidney
i. Filters waste products from the blood stream
ii. Converts filtrate into urine
◦The urinary tract : transports urine out of the
body
- Includes the ureters, urethra and urinary bladder
FUNCTIONS OF THE URINARY SYSTEM
i. Removal of waste products from the body-
urea, uric acid
ii. Storage of urine- urinary bladder can store up
to 1 litre of urine
iii. Excretion of urine through the urethra
iv. Blood volume regulation
v. Regulation of acid base balance
FUNCTIONS OF THE URINARY SYSTEM
vi. Blood pressure maintenance- renin angiotensin
aldosterone system
vii.Regulation of electrolyte balance e.g. Na+, K+
viii.Regulation of erythrocyte production
-Erythropoietin stimulates red blood cell
production in the bone marrow
viii.Vitamin D production
EXTERNAL ANATOMY OF THE KIDNEYS
◦ Two bean shaped organs that lie on either side of the spine
◦ Located in the retroperitoneal space
-Anterior surface covered by the peritoneum
-Posterior surface is against the posterior abdominal wall
◦ Left kidney T12-L3 vertebrae
◦ Right kidney is 2cm lower due to displacement by the liver
◦ Upper portions of the kidneys are protected by the 11th and 12th
ribs
◦ Adrenal glands are found at the superior pole
EXTERNAL ANATOMY OF THE KIDNEYS
◦Hilum- found medially, on the convex indentation of the
kidney
-Is the passage way for blood vessels, nerves, lymphatics
and ureters
The layers that surround the kidneys include:
i. Renal capsule- dense connective tissue that helps the
kidneys maintain their shape and protects them
ii. Renal fat pad- protection
iii. Renal fascia- anchors the kidney to the posterior
abdominal wall
INTERNAL ANATOMY OF THE KIDNEYS
◦Divided into an outer region called the renal cortex and an
inner region called the renal medulla
◦The medulla contains 5-18 renal pyramids that are
separated by renal columns
◦Each pyramid synthesizes urine and terminates into a renal
papilla
◦Renal papilla drains into a minor calyx
◦Several minor calyxes connect to form a major calyx
◦All major calyxes drain into the renal pelvis which connects
to the ureter
INTERNAL ANATOMY OF THE KIDNEY
THE NEPHRON
◦Structural and functional unit of the kidney.
◦Each nephron consists of a blood supply and a
specialised network of ducts called a tubule.
◦Average number is 1 million nephrons per kidney.
THE NEPHRON
◦Parts of the nephron:
i. Renal corpuscle: glomerulus within the Bowman’s
capsule
ii. Renal tubule:
-Proximal convoluted tubule
-Descending limb, loop and ascending loop of Henle
-Distal convoluted tubule
iii. Collecting ducts
THE NEPHRON
THE NEPHRON
◦ All nephron glomeruli are found in the renal cortex
◦ Cortical nephrons- have short loops of Henle
- Penetrate only the outer renal medulla
- 85% of all nephrons in the human body
- Perform the excretory and regulatory functions of the kidney
Juxtamedullary nephrons: have long loops of Henle
- Extend deep into the medulla
- 15% of all nephrons
- Concentrate or dilute urine
CORTICAL VS JUXTAMEDULLARY
BLOOD SUPPLY OF THE KIDNEYS
◦Kidneys receive 20-25% of the cardiac output
◦Renal arteries: 1200 ml of blood per minute
FUNCTIONS OF THE KIDNEY
i. Regulating Acid base balance- through absorption/ secretion
of H+ AND HCO3
-
ii. Regulating Water balance- the kidney ensures that there is
an adequate supply of plasma to keep blood flowing to vital
organs
iii. Maintaining Electrolyte balance
iv. Removes Toxins and waste products from the body
v. Controlling Blood pressure through the RAAS
vi. Produces the hormone Erythropoietin
vii. Activating vitamin D
URETERS
◦Long fibromuscular tubes, 25 cm in length
◦Retroperitoneal
◦Originate at the renal pelvis
◦Extend inferiorly to enter the posterolateral wall
of the base of the urinary bladder
◦Function: transport urine from the kidneys to the
urinary bladder
URINARY BLADDER
◦Expandable muscle container
◦Serves as reservoir for urine
◦Located posterior to the pubic symphysis
◦Trigone :triangular area of the urinary bladder
wall
-Connects the two ureteral openings and the
urethral opening
-Functions as a funnel that directs urine into the
urethra as the bladder wall contracts
URINARY BLADDER
Detrusor muscle – 3 layered smooth muscle
Internal urethral sphincter – made up of smooth
muscle
-Involuntary control
-Controlled by the autonomic nervous system
External urethral sphincter- skeletal muscle
-Voluntary control
-The muscle children learn to control when they are
toilet trained
URINARY BLADDER
Bladder capacity is 400-600ml
At 200-400ml we become conscious of the need to urinate
-Stretch receptors initiate micturition reflex.
-Micturition is the action of urination.
◦ During micturition:
◦ Detrusor muscle contracts
◦ Muscles of pelvic floor and abdominal wall contract
◦ External urinary sphincter relaxes and urine moves from bladder to the
outside
URINARY BLADDER
URETHRA
◦Fibromuscular tube
◦Conducts urine to the exterior of the body
◦Has two sphincters: internal and external
◦Female urethra: 3-5 cm long
-The external urethral orifice is located in the
anterior vaginal wall, between the clitoris and the
vaginal opening
FEMALE URETHRA
URETHRA
◦Male urethra: passageway for both urine and semen
◦Approximately 18-20 cm long
◦Has 3 segments:
i. Prostatic urethra : 3-4 cm long
ii. Membranous urethra- shortest portion
iii. Spongy/penile urethra: longest part,15 cm
-Encased within a cylinder of erectile tissue known as
the corpus spongiosum
-Extends to the external urethral orifice
MALE URETHRA
REVIEW QUESTIONS
1. The right kidney is slightly lower than the left
kidney because?
a. It is slightly smaller
b. It is displaced by the liver
c. It is displaced by the heart
d. It needs protection of the lower ribs
REVIEW QUESTIONS
2. The renal pyramids are separated from each
other by extensions of the renal cortex called?
a. Medullary cortices
b. Renal columns
c. Renal medulla
d. Minor calyces
THANK YOU

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RENAL SYSTEM -BMLS.pptx

  • 2. REVIEW QUESTIONS 1.List five functions of the respiratory system. (5 marks) 2.Which of the following parts of the respiratory system produces sound for speech? a.Oropharynx b.Nasal cavity c.Larynx d.Trachea
  • 3. OBJECTIVES ◦Organs of the urinary system ◦Functions of the urinary system ◦Kidney- parts and functions ◦Ureters ◦Urinary bladder ◦Urethra
  • 4. ORGANS OF THE URINARY SYSTEM ◦2 Kidneys ◦2 Ureters ◦Bladder ◦Urethra
  • 5. ORGANS OF THE URINARY SYSTEM Primary organ is the kidney i. Filters waste products from the blood stream ii. Converts filtrate into urine ◦The urinary tract : transports urine out of the body - Includes the ureters, urethra and urinary bladder
  • 6.
  • 7.
  • 8. FUNCTIONS OF THE URINARY SYSTEM i. Removal of waste products from the body- urea, uric acid ii. Storage of urine- urinary bladder can store up to 1 litre of urine iii. Excretion of urine through the urethra iv. Blood volume regulation v. Regulation of acid base balance
  • 9. FUNCTIONS OF THE URINARY SYSTEM vi. Blood pressure maintenance- renin angiotensin aldosterone system vii.Regulation of electrolyte balance e.g. Na+, K+ viii.Regulation of erythrocyte production -Erythropoietin stimulates red blood cell production in the bone marrow viii.Vitamin D production
  • 10. EXTERNAL ANATOMY OF THE KIDNEYS ◦ Two bean shaped organs that lie on either side of the spine ◦ Located in the retroperitoneal space -Anterior surface covered by the peritoneum -Posterior surface is against the posterior abdominal wall ◦ Left kidney T12-L3 vertebrae ◦ Right kidney is 2cm lower due to displacement by the liver ◦ Upper portions of the kidneys are protected by the 11th and 12th ribs ◦ Adrenal glands are found at the superior pole
  • 11. EXTERNAL ANATOMY OF THE KIDNEYS ◦Hilum- found medially, on the convex indentation of the kidney -Is the passage way for blood vessels, nerves, lymphatics and ureters The layers that surround the kidneys include: i. Renal capsule- dense connective tissue that helps the kidneys maintain their shape and protects them ii. Renal fat pad- protection iii. Renal fascia- anchors the kidney to the posterior abdominal wall
  • 12. INTERNAL ANATOMY OF THE KIDNEYS ◦Divided into an outer region called the renal cortex and an inner region called the renal medulla ◦The medulla contains 5-18 renal pyramids that are separated by renal columns ◦Each pyramid synthesizes urine and terminates into a renal papilla ◦Renal papilla drains into a minor calyx ◦Several minor calyxes connect to form a major calyx ◦All major calyxes drain into the renal pelvis which connects to the ureter
  • 13. INTERNAL ANATOMY OF THE KIDNEY
  • 14. THE NEPHRON ◦Structural and functional unit of the kidney. ◦Each nephron consists of a blood supply and a specialised network of ducts called a tubule. ◦Average number is 1 million nephrons per kidney.
  • 15. THE NEPHRON ◦Parts of the nephron: i. Renal corpuscle: glomerulus within the Bowman’s capsule ii. Renal tubule: -Proximal convoluted tubule -Descending limb, loop and ascending loop of Henle -Distal convoluted tubule iii. Collecting ducts
  • 17. THE NEPHRON ◦ All nephron glomeruli are found in the renal cortex ◦ Cortical nephrons- have short loops of Henle - Penetrate only the outer renal medulla - 85% of all nephrons in the human body - Perform the excretory and regulatory functions of the kidney Juxtamedullary nephrons: have long loops of Henle - Extend deep into the medulla - 15% of all nephrons - Concentrate or dilute urine
  • 19. BLOOD SUPPLY OF THE KIDNEYS ◦Kidneys receive 20-25% of the cardiac output ◦Renal arteries: 1200 ml of blood per minute
  • 20. FUNCTIONS OF THE KIDNEY i. Regulating Acid base balance- through absorption/ secretion of H+ AND HCO3 - ii. Regulating Water balance- the kidney ensures that there is an adequate supply of plasma to keep blood flowing to vital organs iii. Maintaining Electrolyte balance iv. Removes Toxins and waste products from the body v. Controlling Blood pressure through the RAAS vi. Produces the hormone Erythropoietin vii. Activating vitamin D
  • 21.
  • 22.
  • 23.
  • 24.
  • 25.
  • 26.
  • 27.
  • 28.
  • 29.
  • 30.
  • 31.
  • 32.
  • 33.
  • 34.
  • 35.
  • 36.
  • 37.
  • 38.
  • 39. URETERS ◦Long fibromuscular tubes, 25 cm in length ◦Retroperitoneal ◦Originate at the renal pelvis ◦Extend inferiorly to enter the posterolateral wall of the base of the urinary bladder ◦Function: transport urine from the kidneys to the urinary bladder
  • 40. URINARY BLADDER ◦Expandable muscle container ◦Serves as reservoir for urine ◦Located posterior to the pubic symphysis ◦Trigone :triangular area of the urinary bladder wall -Connects the two ureteral openings and the urethral opening -Functions as a funnel that directs urine into the urethra as the bladder wall contracts
  • 41. URINARY BLADDER Detrusor muscle – 3 layered smooth muscle Internal urethral sphincter – made up of smooth muscle -Involuntary control -Controlled by the autonomic nervous system External urethral sphincter- skeletal muscle -Voluntary control -The muscle children learn to control when they are toilet trained
  • 42. URINARY BLADDER Bladder capacity is 400-600ml At 200-400ml we become conscious of the need to urinate -Stretch receptors initiate micturition reflex. -Micturition is the action of urination. ◦ During micturition: ◦ Detrusor muscle contracts ◦ Muscles of pelvic floor and abdominal wall contract ◦ External urinary sphincter relaxes and urine moves from bladder to the outside
  • 44. URETHRA ◦Fibromuscular tube ◦Conducts urine to the exterior of the body ◦Has two sphincters: internal and external ◦Female urethra: 3-5 cm long -The external urethral orifice is located in the anterior vaginal wall, between the clitoris and the vaginal opening
  • 46. URETHRA ◦Male urethra: passageway for both urine and semen ◦Approximately 18-20 cm long ◦Has 3 segments: i. Prostatic urethra : 3-4 cm long ii. Membranous urethra- shortest portion iii. Spongy/penile urethra: longest part,15 cm -Encased within a cylinder of erectile tissue known as the corpus spongiosum -Extends to the external urethral orifice
  • 48. REVIEW QUESTIONS 1. The right kidney is slightly lower than the left kidney because? a. It is slightly smaller b. It is displaced by the liver c. It is displaced by the heart d. It needs protection of the lower ribs
  • 49. REVIEW QUESTIONS 2. The renal pyramids are separated from each other by extensions of the renal cortex called? a. Medullary cortices b. Renal columns c. Renal medulla d. Minor calyces

Editor's Notes

  1. Divided into an outer region called the renal cortex and an inner region called the renal medulla The medulla contains 5-18 renal pyramids that are separated by renal columns Each pyramid synthesizes urine and terminates into a renal papilla Renal papilla drains into a minor calyx Several minor calyxes connect to form a major calyx All major calyxes drain into the renal pelvis which connects to the ureter
  2. Renal corpuscle: glomerulus within the Bowman’s capsule Renal tubule: Proximal convoluted tubule Descending limb, loop and ascending loop of Henle Distal convoluted tubule Collecting ducts
  3. All nephron glomeruli are found in the renal cortex Cortical nephrons- have short loops of Henle Penetrate only the outer renal medulla 85% of all nephrons in the human body Perform the excretory and regulatory functions of the kidney Juxtamedullary nephrons: have long loops of Henle Extend deep into the medulla 15% of all nephrons Concentrate or dilute urine