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Richard Sever, PhD 
Assistant Director, Cold Spring Harbor Laboratory Press 
Twitter: @cshperspectives
Cold Spring Harbor Laboratory, NY
Research at Cold Spring Harbor 
• 600 scientific staff 
• 50 research groups 
• Molecular biology and genetics 
• Cancer 
...
Science education and communication 
Conferences 
• Meetings 
• The Banbury Center 
• Cold Spring Harbor Asia, Suzhou, Chi...
Books 
Research journals 
Review journals
2013: CSHL launched a preprint server for biology
What scientists were saying 
“It’s ridiculous I have to wait months to read a paper while it goes 
through peer review…let...
Biology appearing on the physics arXiv
• A not-for-profit service of CSH Laboratory 
• Makes papers available before consideration by a journal 
• Submission + a...
Features 
• Posted manuscript date-stamped + given a DOI (citable) 
• Indexed in Google Scholar 
• Choice of article type ...
Progress in a year 
• ~1000 submissions (>90% approved) 
• ~30% revised (many more than once) 
• Papers subsequently publi...
Progress in a year 
• Behavior change: more biologists posting/reading 
preprints 
• Policy change: more journals allowing...
• Feedback via social media 
• Feedback via commenting 
• Feedback via email
Making it easier for authors: journal integration 
Formal 
publication 
Submission Peer review 
(not to scale…) 
Preprint ...
Benefits 
• Rapid transmission of results 
• Pre-publication feedback/discussion 
• Visibility, especially for early-caree...
An essential resource
2014 CrossRef Annual Meeting Peer Review Panel: bioRxiv: the preprint server for biology
2014 CrossRef Annual Meeting Peer Review Panel: bioRxiv: the preprint server for biology
2014 CrossRef Annual Meeting Peer Review Panel: bioRxiv: the preprint server for biology
2014 CrossRef Annual Meeting Peer Review Panel: bioRxiv: the preprint server for biology
2014 CrossRef Annual Meeting Peer Review Panel: bioRxiv: the preprint server for biology
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2014 CrossRef Annual Meeting Peer Review Panel: bioRxiv: the preprint server for biology

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Richard Sever of Cold Spring Harbor Laboratory Press describes the bioRxiv preprint server at a panel presentation during the 2014 CrossRef Annual Meeting in London, UK

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2014 CrossRef Annual Meeting Peer Review Panel: bioRxiv: the preprint server for biology

  1. 1. Richard Sever, PhD Assistant Director, Cold Spring Harbor Laboratory Press Twitter: @cshperspectives
  2. 2. Cold Spring Harbor Laboratory, NY
  3. 3. Research at Cold Spring Harbor • 600 scientific staff • 50 research groups • Molecular biology and genetics • Cancer • Neuroscience • Plant biology • Genomics and bioinformatics • Quantitative biology • Ranked #1 in the world in molecular biology & genetics
  4. 4. Science education and communication Conferences • Meetings • The Banbury Center • Cold Spring Harbor Asia, Suzhou, China Teaching • Watson School of Biological Sciences • Residential lab and lecture courses • DNA Learning Center Publishing • Cold Spring Harbor Laboratory Press
  5. 5. Books Research journals Review journals
  6. 6. 2013: CSHL launched a preprint server for biology
  7. 7. What scientists were saying “It’s ridiculous I have to wait months to read a paper while it goes through peer review…let me decide for myself whether it’s any good” “Think how much time is wasted!” “I am writing a grant but the paper is not going to be published by the time I submit. The solution is a pre-print server that can be referenced”
  8. 8. Biology appearing on the physics arXiv
  9. 9. • A not-for-profit service of CSH Laboratory • Makes papers available before consideration by a journal • Submission + access free • Posting almost immediate, with screening but no peer review • Revised versions can be posted any time
  10. 10. Features • Posted manuscript date-stamped + given a DOI (citable) • Indexed in Google Scholar • Choice of article type (New, Confirmatory, or Contradictory Results) • 25 subject categories • Choice of license (CC BY, CC BY-NC, CC BY-ND, CC BY-NC-ND, all rights reserved) • Article metrics • Commenting • Links to published versions
  11. 11. Progress in a year • ~1000 submissions (>90% approved) • ~30% revised (many more than once) • Papers subsequently published in >100 journals Nature, Science, PNAS, eLife, Nature Genetics, Nature Neuroscience, Nature Communications, Genome Research, Genetics, Evolution, Biophysical Journal, PLoS One, PloS Genetics, Biology Open, Bioinformatics, American, Journal of Human Genetics, Journal of Neuroscience, BMC Genomics, BMC Biology, G3, Frontiers in Genetics, Frontiers in Neuroscience, Genome Biology, Interface, Molecular Systems Biology, Nucleic Acids Research, PeerJ, PLoS Computational Biology, Oncogene, Molecular Plant, Journal of Ecology, Epidemiology & Infection, Biochimie, Gigascience
  12. 12. Progress in a year • Behavior change: more biologists posting/reading preprints • Policy change: more journals allowing preprint posting • Rule change: NIH biosketch can now cite preprints
  13. 13. • Feedback via social media • Feedback via commenting • Feedback via email
  14. 14. Making it easier for authors: journal integration Formal publication Submission Peer review (not to scale…) Preprint posted Your journal here
  15. 15. Benefits • Rapid transmission of results • Pre-publication feedback/discussion • Visibility, especially for early-career scientists • Immediate availability to grant/hiring committees
  16. 16. An essential resource

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