doctor at Sapienza University of Rome
Aug. 9, 2009

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  1. 3rd Tinnitus Research Initiative Meeting 24-26 June 2009, Stresa, Italy Tinnitusbook: a proposal for an advanced scientific web community for tinnitus research G. Attanasio (a,f), P. Ciccarese (b,c), E. Wu (e), T. Clark (b,c,d), E. Pecis (f), R. Filipo(a) a: Dept. Neurology and Otolaryngology, University La Sapienza, Rome, IT; b: Massachusetts Gen. Hosp., Boston, MA; c: Harvard Med. School, Boston, MA; d: Harvard Initiative in Innovative Computing, Cambridge, MA; e: Alzheimer Res. Forum Found., Boston, MA; f: Association onlus
  2. forum
  3. OUR PROJECT To create a new interdisciplinary online resource connecting researchers with researchers, to facilitate rapid progress in Tinnitus research COMMUNITY COMMUNITY OF PATIENTS OF SCIENTISTS
  4. 3rd Tinnitus Research Initiative Meeting 24-26 June 2009, Stresa, Italy Building Online Communities for Scientists Tinnitusbook: a proposal for an advanced scientific web community for tinnitus research Paolo Ciccarese, PhD Mass General Hospital / Harvard Medical School In collaboration with Alzheimer Research Forum
  5. Alzheimer Research Forum • Created in 1996 • 58,000 Alzheimer Disease (AD) Related Papers • 1800 AD Related News Articles • Curated 14,700 Antibodies • 5000 Members (AD Scientists) • 6300 Scientists’ Comments • Over 80 live discussions > The CNN of Alzheimer
  6. Alzheimer Research Forum
  7. 58,000 AD Related Papers
  8. 6300 Scientists’ Comments
  9. Over 80 Live Discussions
  10. ARF - People • Executive Editor (June Kinoshita) • 2 Managing Editors • 3 Science Writers • 3 Consultants (Elizabeth Wu for Knowledge Managment) • 1 Drug Database Curator (Gwen Wong, PhD) • 1 Event Coordinator • 1 Web Developer • 1 Production Assistant • 10 Advisory Board …and 5000 Scientists!!!
  11. SWAN - Semantic Web Applications in Neuromedicine • Define Hypotheses, Claims, Research Questions, Comments, Experiments – To relate them in between each others – To relate them to Gene, Protein, Antibodies, Organisms • Annotate Publications (manual and semi- automatic) • Efficient browsing of the knowledge base • Knowledge sharing across communities
  12. SWAN Model
  13. SWAN Homepage
  14. SWAN Hypotheses
  15. SWAN Hypothesis
  16. SWAN Claim Qualifiers Supportive Evidence Relationships with other statements in the KB Lses
  17. SWAN Graph [1]
  18. SWAN Graph [2]
  19. SWAN Graph [3]
  20. Schizophrenia Research Forum
  21. High Number of Resources • PubMed • Reagents • Mash Terminology • Experiments • Entrez Gene • Neuro Imaging • UniProt • Models • Gene Ontology • Annotations • Alzforum Gene • Discussions • Alzforum Antibodies • Commentaries • Experimental Data • …
  22. Science Collaboration Framework • Reusable software that can be used to develop web-based, collaborative, scientific communities • Support interdisciplinary scientists in publishing, annotating, sharing and discussing content such as articles, perspectives, interviews and news items, as well as assert personal biographies and research interests
  24. • It is an open access collection of invited, original, peer-reviewed chapters (46 a few days ago) covering a range of topics related to stem cell biology written by top researchers in the field at the Harvard Stem Cell Institute and worldwide. • ISSN 1940-3429
  25. Table of Contents
  26. Example: Link to genes
  27. Other Stem Book features • eAlert • Commenting and discussion forums • Semiautomatic annotation of Genes in new articles • Access to the under-development clouds of resources for life science (genes, proteins, antibodies, organisms…)
  29. What we can offer • Experience in creating and maintain online communities • Reusable software that can speed up the process of creation of a new community • Access to biomedical knowledge bases • Access to new methods and technologies as result of our research • Be part of a community of communities
  30. Thank you • Tim Clark • Sudeshna Das • Gwen Wong • Benjamin Melançon • June Kinoshita • Marco Ocana • Elizabeth Wu Paolo Ciccarese, PhD