3. ISBN : 0387581537
Author :
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4. The development of new drugs for the treatment of cancer is both medically important and
scientifically challenging. The monograph looks at some of the most exciting prospects, e.g., future
clinical trials, new biological discoveries, and advances in molecular biology. This volume will be of
interest to laboratory scientists in the academic sector and the pharmaceutical industry, as well as to
medical professionals. The particular topics covered are: Experimental models to investigate novel
anticancer drugs - Principles in the design of DNA-interactive molecules - Discovery of improved
platinum analogues - Pharmacological intervention with signal transduction - Discovery and design of
inhibitors of oncogenic tyrosine kinases - Apoptosis and cancer therapy - Engineering antibodies for
targeted cancer therapy
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