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Dr. Ajith Y. MVSc PhD
Assistant Professor
Teaching Veterinary Clinical Complex, COVAS, Mannuthy
Department of Veterinary Clinical Medicine, Ethics and Jurisprudence
Kerala Veterinary andAnimal Sciences University, Pookode
• Equine Respiratory Medicine and Surgery 1st Edn by McGorum
B., Robinson N.E., Schumacher J., Dixon P. (2006) Elsevier/Saunders.
• Equine Respiratory Diseases by Rush B., Mair T. (2004) Wiley.
• Equine Internal Medicine 4th Edn by Reed S., Bayly W., Sellon D. (2017)
Elsevier/Saunders.
• Equine Sports Medicine and Surgery 2nd Edn by Hinchcliff K.W., Kaneps
A.J., Geor R.J. (2013) Elsevier/Saunders.
• Equine Neonatal Medicine and Surgery 1st Edn by Knottenbelt D., Holdstock
N., Madigan J. (2004) Elsevier/Saunders.
• Saunders Equine Formulary 2nd Edn by Knottenbelt D., Malalana F.
• Journal of Equine Veterinary Science Elsevier (Impact Factor: 1.100)
• Equine Veterinary Journal Wiley Online (Impact Factor: 2.477)
• Veterinary Clinics of North America: Equine Practice Elsevier (IF: 0.770)
• Respiratory health is important in the athletic
performance of horses (Examine during rest and exercise).
• Even a mild disease affecting lung capacity may make
the animal useless.
• Anatomical and Physiological protective mechanisms
- Turbinates & mucus covered epithelium (filters upto 5 µm)
- Mucus and Mucosal IgA secretion is more
- Cough reflex, Ciliated epithelium helps in swallowing
- Large soft palate – ‘Mouth is for eating, not for respiration’
• More immune cells (esp macrophages) and highly
vascular - Alveolar phagocytosis
• Shock organ of equine – Lungs and intestines
(Dog – Liver and GI tract; Ruminants, Cats – Lungs; Human - Heart)
• LRT infections mainly due to flare up of normal
commensals present in URT
• Stress… (transport, housing and ventilation)
• Obstruction or trauma or lack of rest
• In young, Congenital & Developmental disorders
– Choanal atresia, Cysts, lung hypoplasia, hyperkalemic
periodic paralysis (skeletal Na+ channels affected)
• Ventilation and housing details
• Aberrant /Recent changes and STRESS
• Exercise Induced Pulmonary Hemorrhage (EIPH)
• Climate/Weather….Humidity and Pollen grains
• Respiratory Rate (8-12 breaths pm)
• Efforts/Difficulty (Inspiratory-Upper/Expiratory-Lower)
• Pattern (abdominal/thoracic)
• Extended head and neck, Nasal flare
• Stertor (low pitch) vs Stridor (High pitch)
• Location - Snoring, Roaring, Wheezes, Crackles
• Nasal discharges (Unilateral/Bilateral)
• Type of discharges (Serous, Mucous, Serosanguinous,
Purulent, Epistaxis, Hemaptysis in horse?)
• Palpation, Percussion - pleural effusions, Auscultation
Maxillary sinusitis (Unilateral swelling)
• GROSS & Microscopic evaluation of Aspirate/Smear-
Cytology/Bacteriology/Mycology/FNAC (Maxillary swelling)
• Thoraco/Pleurocentesis and Thoracoscopy
• Lung Biopsy (Miliary TB, Neoplasms, Fibrosis)
• Tracheobroncheal Aspiration – Invasive technique
• Broncho Alveolar Lavage (BAL) (through nasal)
• Radiography & Thoracic USG (difficult due to air)
• Culture (bacterial, fungal, viral) and Sensitivity testing
• Endoscopy- Rhinoscopy, Bronchoscopy, Laryngoscopy
• Arterial Blood Gas Analysis
• Tidal Volume, Inspiratory volume, Expiratory Volume,
Frequency
• VIRUS – Equine Influenza Virus (EIV), Equine Herpes
Virus (EHV 1-5), Equine Rhino Virus, Equine Adeno Virus,
African Horse Sickness (Dunkop)
• BACTERIA – Streptococcus equi , Rhodococcus equi,
Mycoplasma sp., Burkholderia mallei (granuloma),
Staphylococcus sp.
• FUNGUS – Aspergillus sp. (chronic)
• PARASITES – Myiasis by Habronema muscae, Draschia
megastoma
• NEOPLASMS – Sinus tumours, Metastatic in lungs
EHV 5 causes Equine Multinodular Pulmonary Fibrosis
• Mostly unilateral, Bilateral in viral infections
• Treatment: Debridement, Draining and flushing, local antiseptic,
oral/systemic antibiotics and antifungals, surgical ostectomy
• Etiology similar to sinusitis; GP empyema, GP mycosis
• Nasal discharge, submandibular lymphadenopathy, Inspiratory
sounds, Dysphagia, Neuropathy
• Antibiotic + Surgical drainage
• CHONDROIDS – Inspissated pus with cottage cheese like appearance
in guttural pouch
• Purpura hemorrhagica - Aseptic necrotizing vasculitis (Type III)
characterized by edema and petechial or ecchymotic hemorrhage.
• Other signs of Sinusitis, Pneumonia, Septicemia
• Left Recurrent Laryngeal Nerve is more affected (more length)
• ROARING
• CORDECTOMY & VENTRICULECTOMY or Prosthetic laryngeoplasty
• It is the non-infectious condition causing breathing difficulty due
to narrow airways and excess mucuos due to hyper sensitive/
uncontrolled inflammatory response.
B) Heaves / Equine Recurrent
Airway Obstruction
- Severe equine asthma
- In Adult animals
- Like COPD in human
A) Inflammatory Airway Disease
- Mild to moderate equine
asthma
- In Young animals
i) Antibiotics/ Chemotherapeutic agents/Antiparasitic/Antifungal
ii) Antiinflammatory
- NSAIDs may not be enough
- Corticosteroids (Hydrocortisone, Prednisolone, Dexamethasone)
- Inhaled Corticosteroids (Beclomethasone, Budesonide, Fluticazone)
aerosolized
iii) Antihistamines
iv) Bronchodialators
- Beta 2 – adrenergic agonists (Salbutamol, Clenbuterol)
- Methyl Xanthines
- Parasympatholytics (Ipatropium bromide)
v) Mucolytics/Expectorant (Commercial preparations, Ammo Chlor, NAC)
1. Define eg- COPD, EIPH, Roaring, Chondroids…..
2. Specific etiological agents – eg: Strangles – S. equi. Left recurrent LN
3. Short Notes and Essays - eg: Heaves, Guttural pouch empyema
ajithy@kvasu.ac.in
ajithy123456789@gmail.com
+91 8891981301 (WhatsApp)
Respiratory diseases of horses

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Respiratory diseases of horses

  • 1. Dr. Ajith Y. MVSc PhD Assistant Professor Teaching Veterinary Clinical Complex, COVAS, Mannuthy Department of Veterinary Clinical Medicine, Ethics and Jurisprudence Kerala Veterinary andAnimal Sciences University, Pookode
  • 2.
  • 3. • Equine Respiratory Medicine and Surgery 1st Edn by McGorum B., Robinson N.E., Schumacher J., Dixon P. (2006) Elsevier/Saunders. • Equine Respiratory Diseases by Rush B., Mair T. (2004) Wiley. • Equine Internal Medicine 4th Edn by Reed S., Bayly W., Sellon D. (2017) Elsevier/Saunders. • Equine Sports Medicine and Surgery 2nd Edn by Hinchcliff K.W., Kaneps A.J., Geor R.J. (2013) Elsevier/Saunders. • Equine Neonatal Medicine and Surgery 1st Edn by Knottenbelt D., Holdstock N., Madigan J. (2004) Elsevier/Saunders. • Saunders Equine Formulary 2nd Edn by Knottenbelt D., Malalana F. • Journal of Equine Veterinary Science Elsevier (Impact Factor: 1.100) • Equine Veterinary Journal Wiley Online (Impact Factor: 2.477) • Veterinary Clinics of North America: Equine Practice Elsevier (IF: 0.770)
  • 4. • Respiratory health is important in the athletic performance of horses (Examine during rest and exercise). • Even a mild disease affecting lung capacity may make the animal useless. • Anatomical and Physiological protective mechanisms - Turbinates & mucus covered epithelium (filters upto 5 µm) - Mucus and Mucosal IgA secretion is more - Cough reflex, Ciliated epithelium helps in swallowing - Large soft palate – ‘Mouth is for eating, not for respiration’
  • 5. • More immune cells (esp macrophages) and highly vascular - Alveolar phagocytosis • Shock organ of equine – Lungs and intestines (Dog – Liver and GI tract; Ruminants, Cats – Lungs; Human - Heart) • LRT infections mainly due to flare up of normal commensals present in URT • Stress… (transport, housing and ventilation) • Obstruction or trauma or lack of rest
  • 6.
  • 7.
  • 8. • In young, Congenital & Developmental disorders – Choanal atresia, Cysts, lung hypoplasia, hyperkalemic periodic paralysis (skeletal Na+ channels affected) • Ventilation and housing details • Aberrant /Recent changes and STRESS • Exercise Induced Pulmonary Hemorrhage (EIPH) • Climate/Weather….Humidity and Pollen grains
  • 9. • Respiratory Rate (8-12 breaths pm) • Efforts/Difficulty (Inspiratory-Upper/Expiratory-Lower) • Pattern (abdominal/thoracic) • Extended head and neck, Nasal flare • Stertor (low pitch) vs Stridor (High pitch) • Location - Snoring, Roaring, Wheezes, Crackles • Nasal discharges (Unilateral/Bilateral) • Type of discharges (Serous, Mucous, Serosanguinous, Purulent, Epistaxis, Hemaptysis in horse?)
  • 10. • Palpation, Percussion - pleural effusions, Auscultation Maxillary sinusitis (Unilateral swelling)
  • 11. • GROSS & Microscopic evaluation of Aspirate/Smear- Cytology/Bacteriology/Mycology/FNAC (Maxillary swelling) • Thoraco/Pleurocentesis and Thoracoscopy • Lung Biopsy (Miliary TB, Neoplasms, Fibrosis) • Tracheobroncheal Aspiration – Invasive technique • Broncho Alveolar Lavage (BAL) (through nasal) • Radiography & Thoracic USG (difficult due to air) • Culture (bacterial, fungal, viral) and Sensitivity testing • Endoscopy- Rhinoscopy, Bronchoscopy, Laryngoscopy
  • 12. • Arterial Blood Gas Analysis • Tidal Volume, Inspiratory volume, Expiratory Volume, Frequency
  • 13. • VIRUS – Equine Influenza Virus (EIV), Equine Herpes Virus (EHV 1-5), Equine Rhino Virus, Equine Adeno Virus, African Horse Sickness (Dunkop) • BACTERIA – Streptococcus equi , Rhodococcus equi, Mycoplasma sp., Burkholderia mallei (granuloma), Staphylococcus sp. • FUNGUS – Aspergillus sp. (chronic) • PARASITES – Myiasis by Habronema muscae, Draschia megastoma • NEOPLASMS – Sinus tumours, Metastatic in lungs EHV 5 causes Equine Multinodular Pulmonary Fibrosis
  • 14. • Mostly unilateral, Bilateral in viral infections • Treatment: Debridement, Draining and flushing, local antiseptic, oral/systemic antibiotics and antifungals, surgical ostectomy
  • 15. • Etiology similar to sinusitis; GP empyema, GP mycosis • Nasal discharge, submandibular lymphadenopathy, Inspiratory sounds, Dysphagia, Neuropathy
  • 16. • Antibiotic + Surgical drainage • CHONDROIDS – Inspissated pus with cottage cheese like appearance in guttural pouch
  • 17. • Purpura hemorrhagica - Aseptic necrotizing vasculitis (Type III) characterized by edema and petechial or ecchymotic hemorrhage. • Other signs of Sinusitis, Pneumonia, Septicemia
  • 18. • Left Recurrent Laryngeal Nerve is more affected (more length) • ROARING • CORDECTOMY & VENTRICULECTOMY or Prosthetic laryngeoplasty
  • 19. • It is the non-infectious condition causing breathing difficulty due to narrow airways and excess mucuos due to hyper sensitive/ uncontrolled inflammatory response. B) Heaves / Equine Recurrent Airway Obstruction - Severe equine asthma - In Adult animals - Like COPD in human A) Inflammatory Airway Disease - Mild to moderate equine asthma - In Young animals
  • 20. i) Antibiotics/ Chemotherapeutic agents/Antiparasitic/Antifungal ii) Antiinflammatory - NSAIDs may not be enough - Corticosteroids (Hydrocortisone, Prednisolone, Dexamethasone) - Inhaled Corticosteroids (Beclomethasone, Budesonide, Fluticazone) aerosolized iii) Antihistamines iv) Bronchodialators - Beta 2 – adrenergic agonists (Salbutamol, Clenbuterol) - Methyl Xanthines - Parasympatholytics (Ipatropium bromide) v) Mucolytics/Expectorant (Commercial preparations, Ammo Chlor, NAC)
  • 21. 1. Define eg- COPD, EIPH, Roaring, Chondroids….. 2. Specific etiological agents – eg: Strangles – S. equi. Left recurrent LN 3. Short Notes and Essays - eg: Heaves, Guttural pouch empyema