Micro-encapsulation involves applying a thin coating of between 100-5000 microns to small particles or droplets to alter their properties. It has several advantages over tablet coating like converting liquids to solids, modifying surface properties, and allowing for wider distribution and absorption in the gastrointestinal tract. However, no single microencapsulation process is suitable for all materials and it can be non-reproducible and economically limiting. Micro-encapsulation has applications in stabilizing core materials, separating reactive ingredients, and controlling release. Common microencapsulation processes include air suspension, coacervation, spray drying, polymerization, and pan coating.

1. Micro-Encapsulation
Prepared By
Ajay Chavan

2. MICRO-ENCAPSULATION
Micro - (Small)
Encapsulation -(Capsule formation)
It Is defined as the applying relatively thin coating
to small particles of solids or droplets of liquids
and dispersions.
Coating size Range:– 100 – 5000Micron

3. Advantages of Micro-Encapusulation over Tablet
Coating
Micro-
Encapsulation
• Converting liquid into
flowable solids
• Alters colloidal and surface
properties
• Smallness of coating size
• Adaption to wide variety of
dosage form
• Distribution widely
throughout GIT
• Drug absorption is more
Tablet Coating
• Solid to solid only
• Coating size large incase
of suger coating
• Adapt only over tablet
• Distribution is slow
• Drug absorption is slow
compare to Micro-
Encapsulation

4. Disadvantages of Micro-Encapsulation
• No single microencapsulation process is adaptable to
all core material candidates or product application
• Non reproducible
• Economic limitations

5. Application Of Micro-Encapsulation (SSC)
• Stabilization of core material
• Sepration of chemically reactive
ingridients
• Control of Release of core materials

6. Types of Micro-Encapsulation
Process
1.Air Suspension
2.Coacervation– phase Separation
3.Spray Dryimg
4.Polymerization
5.Pan Coating

7. Summary
What is microencapsulation?
Advantages and Disadvantages
Applications
Tyeps of Processes.

8. THANK YOU