4. ORTHOPNEA
• Shortness of breath when lying down (recumbent position)
• Relieved by sitting up or elevation of head with pillows
• Occurs within 1-2 minutes after lying down
• Examples : Congestive cardiac failure (CCF), asthma, bilateral paralysis of diaphragm
MECHANISM OF ORTHOPNEA
Lying down / Horizontal position
↓
Redistribution of blood volume from lower extremities to the
heart ( increased venous return )
↓
In left ventricular failure, not able to pump out extra volume of
blood
↓
Backflow of blood to the lung
↓
Pulmonary congestion
↓
Dyspnea
Diaphragm paralysis
or lung collapse
↓
Elevated diaphragm
↓
↓ vital capacity
5. PAROXYSMAL NOCTURNAL DYSPNEA
• Shortness of breath which occur at night and makes the patient wake up from sleep
• Occur usually 1-2 hours after sleep
• Shorter duration of dyspnea (10-30 min)
• Example : Left sided failure / Cardiac asthma
MECHANISM OF PND
Due to gradual reabsorption of lower extremity
interstitial edema into the circulation
↓
↑ intravascular blood volume
↓
↑ venous return to the heart and lung
↓
Pulmonary congestion
↓
Dyspnea
6. PLATYPNEA
• Shortness of breath occurs when in upright position (sitting/standing)
• Relieved by supine position
• Examples : Pulmonary AV malformation, hepatopulmonary syndrome
MECHANISM OF PLATYPNEA
Upright (Sitting position)
↓
Gravitational force causes more blood goes to lower
zone of lung
↓
↑ perfusion and ↓ ventilation
↓
V/Q mismatch
↓
Dyspnea
7. TREPOPNEA
Shortness of breath when lying on one side (lateral recumbent position)
Relieved by lying on opposite side
Causes : Unilateral lung disease, CHF
MECHANISM OF TREPOPNEA
Patient lies on affected side
↓
Gravitational force causes more blood goes to lower zone of
lung
↓
↑ perfusion and ↓ ventilation in diseased organ
↓
V/Q mismatch ( increased shunting )
↓
hypoxemia
↓
Worsen dyspnea
9. In Ralston, S. H., In Penman, I. D., In Strachan, M. W. J., & In Hobson, R. P. (2018). Davidson's
principles and practice of medicine.
P. J. Mehta (2018). Common Medical Symptoms.
Mukerji V. Dyspnea, Orthopnea, and Paroxysmal Nocturnal Dyspnea. In: Walker HK, Hall WD,
Hurst JW, editors. Clinical Methods: The History, Physical, and Laboratory Examinations. 3rd
edition. Boston: Butterworths; 1990. Chapter 11. Available from:
https://www.ncbi.nlm.nih.gov/books/NBK213/
REFERENCES