This document lists various diseases caused by Staphylococcus aureus including SSSS, impetigo, empyema, pneumonia, folliculitis, carbuncles, osteomyelitis, toxic shock syndrome, conjunctivitis, and food poisoning. It provides an overview of S. aureus describing it as a gram-positive coccus that grows in grapelike clusters, is catalase positive, and coagulase positive. Risk factors for infection include catheters, direct contact, surgical procedures, contaminated bed linens, and antibiotics that suppress normal microflora. The diagnosis involves catalase testing and growing the bacteria on selective and non-selective media, while treatment includes oxacillin, van

2. DISEASES:
◦ SSSS.
◦ IMPETICO.
◦ EMPYEMA.
◦ PNEUMONIA .
◦ FOLLICULITIS.
◦ CARBUNCULES.
◦ OSTEOMYELITIS.
◦ TOXIC SHOCK S.
◦ CONJUNCTIIVITS.
◦ FOOD POISONING.
◦ SEPTIC ARTHRITIS.
◦ ABSCESS – FURUNCLES.
◦ BACTERIEMIA – ENDOCARDITIS.

3. SSSS (Staphylococcus Scalded Skin Syndrome)
FOOD POISONING
TOXIC SHOCK S.

4.  OVERVIEW;OVERVIEW;
 Gram Positive Coccus.
 Grapelike Cocci (Clusters).
 Catalase Positive:
Hydrogen Peroxide Water+Oxygen
THUS protection from neutrophil.
 Coagulase Positive:
FIBRINOGEN Fibrin CLOT FORMATION
 Colonies are GoldGold.
 Normal flora .. Nose and Vagina(5%) Toxic shock Syndrome.
 Survive on DRY surface for longer period.
 MRSA.

5. PROTECTION.
ATTACHMENT.
ENDOTOXIN.
FIBRONOCTIN.
ANTIBODY INHIBITION.

6. 2. Toxins:
I. CYTOTOXINS
II. EXOFOLIATIVE
III. ENTEROTOXIN
IV. Toxic Shock S. T.
TOXIN for WBCs.
SPLIT INTRACELLULAR BRIDGES.
ENDOTHHELIAL CELL DESTRUCTION.
INTESTINAL PERISTALSIS.

7. 3. Enzymes:
I. COAGULASE
II. HYALURONIDASE
III. FIBRINOLYSIN
IV. LIPASES
V. NUCLEASES
SPREAD IN TISSUES.
HYDROLYSES LIPIDS.
DISSLOVE FIBRIN CLOTS.
CLOT FORMATION.
HYDROLYSES DNA.

8. Risk Factors:
1. Catheters.
2. Direct Contact.
3. Surgical Procedure.
4. Contaminated bed linens.
5. Antibiotic that suppress
the normal microflora.

9. DIAGNOSIS:
I.Catalase Test.
II.Grows rapidly on non-selective media.
III.Selective media can be used to recover S. aureus
in contaminated specimens.
TREATMENT:
I.Oxacillin.
II.Vancomycin.
III.Trimethoprim.
PREVENTION:
I.Hand washing – Personal hygiene.
II.Proper cleaning of wounds - Usage of disinfectant.