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WELCOME TO
TOPIC
PRESENTATIO
N
DR. ASIF SARWAR
INDOOR MEDICAL OFFICER
DEPT. OF ORTHOPAEDICS,
JRRMCH
EXTRAPULMONARY TB
• DEFINATION:
• Extra pulmonary TB refers to tuberculosis of organ or any tissue
other than lung.
SITES OF EPTB
• Extra pulmonary TB can occurs in multiple site with relative
frequencies of –
• LYMPHNODE – 42%
• PLEURA – 18%
• BONES & JOINTS – 12%
• GENITOUTERINE – 6%
• MENINGEAL – 6%
• PERITONEAL – 5%
• OTHERS – 11%
SIGNS AND SYMPTOMS :-
• LYMPHNODE –
• Painless enlarged cervical lymphadenopathy with or without sinus
formation.
• BONES AND JOINTS –
• Non-painful or painful enlarged joint
• Unable to walk or movement
• LBP
• Deformity
• MENINGES –
• Raised intracranial pressure
• Raised temperature
• OTHERS –
• Pleural effusion;
• Pericardial effusion;
• Distended abdomen with ascites
BONES AND JOINTS TB
• Weight bearing joints are mostly
affected. Tuberculosis of the hip
joints causes pain and limping. TB
of the knee produces pain and
swelling. A history of previous
trauma is often elicited.
Radiological abnormalities include
bone erosions, joint space
narrowing, and ultimately joint
destruction. Diagnosis requires
synovial biapsy
Spinal TB (pott’s diseases)
• The sites most commonly involved are the lower thoracic
vertebrae and upper lumbar spine but the cervical spine can
also be affected. TB starts in an intervertebral disc and spreads
along the anterior and longitudinal ligaments, before involving
the adjacent vertebral bodies. With advanced disease, collapse
of vertebral bodies‟ results in kyphosis (gibbus). A para-vertebral
cold abscess may also form.
• The typical appearance is erosion of the anterior edges of the
superior and inferior borders of adjacent vertebral bodies. The
disc space is narrowed. CT scan or MRI reveals the lesions
more correctly. Aspiration of the abscess or bone biopsy
confirms the tuberculosis etiology by histopathology and culture.
MRI OF SPINE
DAIGNOSIS OF EPTB
TREATMENT
DRUGS-
• 1ST LINE DRUGS-
• ISONIAZIDE
• RIFAMPICIN
• PYRIZINAMIDE
• ETHUMBUTOL
• STREPTOMYCIN
• 2ND LINE DRUGS-
• FLUROQUINOLOLS
(CIPROFLOXACIN,
LEVOFLOXACIN,
MOXIFLOXACIN)
• AMIKACIN
• PARA-AMINO SALICYLIC
ACID (PAS)
• LINEZOLID
• DELAMANID
• BEDAQULINE
DURATION OF RX OF EPTB
• TYPES DURATION
• LYMPHNODE 6M
• UROGENITAL 6M
• PLEURA 6M
• ABDOMINAL 6M
• TB MENINGITIS 9-12M
• SPINAL TB 12-18M
• BONES AND JOINTS 12-18M
THANK YOU
…

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EPTB Presentation.pptx

  • 1. WELCOME TO TOPIC PRESENTATIO N DR. ASIF SARWAR INDOOR MEDICAL OFFICER DEPT. OF ORTHOPAEDICS, JRRMCH
  • 2. EXTRAPULMONARY TB • DEFINATION: • Extra pulmonary TB refers to tuberculosis of organ or any tissue other than lung.
  • 3. SITES OF EPTB • Extra pulmonary TB can occurs in multiple site with relative frequencies of – • LYMPHNODE – 42% • PLEURA – 18% • BONES & JOINTS – 12% • GENITOUTERINE – 6% • MENINGEAL – 6% • PERITONEAL – 5% • OTHERS – 11%
  • 4. SIGNS AND SYMPTOMS :- • LYMPHNODE – • Painless enlarged cervical lymphadenopathy with or without sinus formation. • BONES AND JOINTS – • Non-painful or painful enlarged joint • Unable to walk or movement • LBP • Deformity • MENINGES – • Raised intracranial pressure • Raised temperature
  • 5. • OTHERS – • Pleural effusion; • Pericardial effusion; • Distended abdomen with ascites
  • 6. BONES AND JOINTS TB • Weight bearing joints are mostly affected. Tuberculosis of the hip joints causes pain and limping. TB of the knee produces pain and swelling. A history of previous trauma is often elicited. Radiological abnormalities include bone erosions, joint space narrowing, and ultimately joint destruction. Diagnosis requires synovial biapsy
  • 7.
  • 8. Spinal TB (pott’s diseases) • The sites most commonly involved are the lower thoracic vertebrae and upper lumbar spine but the cervical spine can also be affected. TB starts in an intervertebral disc and spreads along the anterior and longitudinal ligaments, before involving the adjacent vertebral bodies. With advanced disease, collapse of vertebral bodies‟ results in kyphosis (gibbus). A para-vertebral cold abscess may also form. • The typical appearance is erosion of the anterior edges of the superior and inferior borders of adjacent vertebral bodies. The disc space is narrowed. CT scan or MRI reveals the lesions more correctly. Aspiration of the abscess or bone biopsy confirms the tuberculosis etiology by histopathology and culture.
  • 12.
  • 13. DRUGS- • 1ST LINE DRUGS- • ISONIAZIDE • RIFAMPICIN • PYRIZINAMIDE • ETHUMBUTOL • STREPTOMYCIN • 2ND LINE DRUGS- • FLUROQUINOLOLS (CIPROFLOXACIN, LEVOFLOXACIN, MOXIFLOXACIN) • AMIKACIN • PARA-AMINO SALICYLIC ACID (PAS) • LINEZOLID • DELAMANID • BEDAQULINE
  • 14. DURATION OF RX OF EPTB • TYPES DURATION • LYMPHNODE 6M • UROGENITAL 6M • PLEURA 6M • ABDOMINAL 6M • TB MENINGITIS 9-12M • SPINAL TB 12-18M • BONES AND JOINTS 12-18M