Gro els

GroEL-GroES Chaperonin Complex PDB ID = 1AON

What are Chaperonins? ,[object Object],[object Object]

Where can chaperonins be found? ,[object Object],[object Object],[object Object]

Causes of Aggregations ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Consequences of Aggregation ,[object Object],[object Object]

Chaperonins counteract non-native protein aggregation ,[object Object]

Experimental Details ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

GroEL-GroES Architecture E = E. coli ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

GroEL-GroES Architecture Equatorial = pink Intermediate = yellow Apical = blue Polar + Charge = blue Hydrophobic = yellow Backbone = white Solvent-Excluded surfaces = gray

GroEL-GroES Sequences 8337 Residues 58884 Atoms Equatorial = orange Intermediate = purple Apical = cyan

GroES Domain ,[object Object],[object Object]

GroEL Domains ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Conformational Change of Cavity

How do chaperonins work? ,[object Object],[object Object]

Overall Chaperonins Protein Folding Reaction ,[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

1AON chain A = red 1A6E chain A = yellow 1A6D chain A = green 1A6E Thermosome - Mg-ADP-Alf3 Complex 1A6D Thermosome From T. Acidophilum Ca 4.15A 87 atoms Ca 4.58 A 87 atoms

Structural Neighbors ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

ALDEHYDE DEHYDROGENASE (CHAIN A) PDB ID: 1BPW

Gro els

Recommended

Recommended

More Related Content

What's hot

What's hot (19)

Viewers also liked

Viewers also liked (18)

Similar to Gro els

Similar to Gro els (20)

Recently uploaded

Recently uploaded (20)

Gro els