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MO Figure 
Sensory Receptors 
and the CNS 
Perennou Nuridsany/Science Source.
Sensory pathways 
Involve four steps 
• Sensory reception: sensory receptors 
detect a stimulus 
• Sensory transduction: in response to 
the stimulus, ion channels open or close, 
which changes the membrane potential 
• Transmission: an action potential is 
carried to the CNS 
• Perception: awareness of the stimulus 
occurs in the brain.
Figure 1 
Sensory reception
Figure 1a
Figure 1b
Figure 2 
Amplification 
Amplification is the 
process through which a 
signal is strengthened; 
often involves signal 
transduction pathways.
Figure 2a
Figure 2b
Sensory perception 
Integration: several weak stimuli are added into one 
large perceived stimulus. Occurs at several steps: 
• During signal transduction, separate stimuli are 
added together to generate an action potential. 
• During transmission, several rapid action potentials 
are integrated into one. 
• In the CNS, signals from multiple sensory cells are 
integrated into one signal.
Sensory adaptation 
Sensitivity of sensory receptors changes 
in response to constant stimulation 
• Enables an animal to adjust to 
changing environmental conditions. 
• Enables an animal to ignore constant 
stimuli that might otherwise be 
distracting.
Types of sensory receptor 
• Mechanoreceptors 
• Chemoreceptors 
• Electromagnetic receptors 
• Thermoreceptors 
• Nociceptors (pain receptors)
Mechanoreceptors 
• Respond to mechanical stimulation, such 
as pressure and sound. 
• Responsible for senses of touch and 
hearing 
• Ion channels open or close in response to 
deformation or movement.
Figure 3 
Skin mechanoreceptors 
Sensory 
receptors in the 
skin and 
surrounding hair 
follicles respond 
to pressure.
Figure 4 
Lateral line system 
Used to sense movement 
of water.
Figure 4a
Figure 4b
Chemoreceptors 
Bind chemicals, responsible for senses of taste 
and smell. 
Olfaction: sense of smell, involves detection of 
airborne chemicals called odorants. 
Gustation: sense of taste, involves detection of 
dissolved chemicals called tastants. 
Aquatic animals do not have distinct senses of 
taste and smell.
Figure 5 
Pheromones 
for navigation 
Lampreys detect 
pheromones secreted 
by the larvae of their 
species to navigate to 
breeding sites. 
(a) Jacana/Science Source. (b) 
Gary Meszaros/Science Source.
Electromechanical receptors 
• Detect electromagnetic energy such as light, 
electricity, and magnetism 
• Photoreceptors detect light and are responsible for 
vision. 
Visual organs: 
Eyespots (planaria): sense light and dark 
Compound eyes (insects): detect motion. 
Single-lens eyes (vertebrates and some invertebrates): 
focus image.
Figure 6 
Photoreception 
Planaria move away from light sources using 
photosensitive eyespots.
Figure 7 
Electromagnetic reception 
Monarch butterflies 
use magnetite to orient 
themselves with 
respect to Earth’s 
magnetic field and 
navigate during winter 
migrations. 
Courtesy of Gene Nieminen/USFWS.
Thermoreceptors 
Sense changes in temperature
Nociceptors 
(pain receptors) 
• Detect injurious stimuli such as extreme 
heat, pressure, and dangerous chemicals. 
• In humans, many nociceptors are naked 
dendrites of other types of receptors; 
thermoreceptors, mechanoreceptors, and 
chemoreceptors can act as nociceptors.
MO Figure Auditory and 
Balance System 
Courtesy of B. Peterson/USFWS.
Figure 1 
The Auditory System
Figure 2 
The Cochlea 
Primary site of auditory sense reception. Contains 
the fluid-filled vestibular and tympanic canals. 
Vibration of the basilar membrane causes cilia on 
hair cells to bend. Signals are transmitted to the 
brain through the auditory nerve.
Figure 2a
Figure 2b
Figure 2c
Figure 3 
Hair 
cells 
Bend back and forth in 
response to fluid 
movements from sound 
waves. The bending 
movements are translated 
into neural signals that are 
transmitted to the brain. 
© 2004 Nature Publishing Group Modified from Frolenkov, G. I., et al., Genetic insights 
into the morphogenesis of inner ear hair cells. Nature Reviews Genetics 5, 489–498 
(2004) doi:10.1038/nrg1377. Used with permission.
Figure 4 
Mechanism 
of hearing
Figure 4a
Figure 4b
Figure 4c
Figure 5 
Mechanism of hearing 
The basilar 
membrane 
gets thinner 
and more 
flexible 
toward the 
center of the 
cochlea.
Figure 5a 
Mechanism of hearing
Figure 5b 
Mechanism of hearing 
The basilar membrane gets thinner and more 
flexible toward the center of the cochlea.
Figure 6 
The balance systems
Figure 6a
Figure 6b
Figure 6c
Figure 7 
Semicircular canals 
© 2007 Nature Publishing Group Sanlaville D. & Verloes, A. CHARGE syndrome: an update. European Journal of 
Human Genetics 15, 389–399 (2007) doi:10.1038/sj.ejhg.5201778. Used with permission. 
Clearly visible in normal newborns (left) and 
missing in CHARGE affected newborns (right).
MO Figure 
Vision 
Courtesy of Gary M. Stolz/USFWS.
Figure 1 
Eyespots 
Planaria have primitive eyespots with 
photosensitive tissue. 
Eric V. Grave/Science Source.
Figure 2 
Compound eyes 
Thomas Shahan/Science Source. 
Contain many ommatidia, each with its own 
lens. Highly sensitive to motion.
Figure 3 
Eye and retina anatomy
Figure 3a
Figure 3b
Figure 4 
Microscope vs. eyes 
Both have lenses that refract light. 
Both can focus an image. 
Both have an iris that adjusts light 
levels.
Figure 4a
Figure 4b
Figure 5 
Myopia, hyperopia, 
and astigmatism 
Abnormal curvature of the lens or cornea results 
in light focusing incorrectly on the retina.
Figure 5a
Figure 5b
Figure 5c
Figure 6 
Retinal 
neurons 
Several types of neurons in 
the retina communicate with 
each other to refine, sharpen, 
and process visual stimuli. 
These include bipolar cells 
(green), rod photoreceptors 
(red/purple), cones, amacrine 
cells, ganglion cells, and 
others. 
© 2010 Nature Publishing Group Markus, A. Speedy rod 
signaling. Nature Neuroscience 13, 410 (2010) 
doi:10.1038/nn0410-410. Used with permission.
Figure 7 
Visual processing 
Although images are inverted at the retina, the visual cortex of the 
brain reorients the images properly.
MO Figure 
Taste and Smell 
Picture Partners/Science Source.
Figure 1 
Chemoreceptors 
Robert Noonan/Science Source. 
Insects have olfactory receptors that are typically 
found on their antennae. Gustatory receptors can 
be found on mouthparts and legs.
Figure 2 
Taste buds 
Associated 
with papillae of 
the tongue. 
Contain cells 
that detect 
sweet, salty, 
bitter, sour, and 
umami (savory) 
tastes.
Figure 2a
Figure 2b
Figure 2c
Figure 3
Figure 4 
Olfaction 
Greg Dimijian/Science Source. 
Skunks use odorants for defense.
Figure 5 
The 
olfactory 
pathway 
Binding of odorants 
to chemoreceptor 
neurons triggers 
action potentials that 
are transmitted to 
the olfactory bulb 
and brain.
Figure 5a
Figure 5b

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Sensory Receptors and the CNS

  • 1. MO Figure Sensory Receptors and the CNS Perennou Nuridsany/Science Source.
  • 2. Sensory pathways Involve four steps • Sensory reception: sensory receptors detect a stimulus • Sensory transduction: in response to the stimulus, ion channels open or close, which changes the membrane potential • Transmission: an action potential is carried to the CNS • Perception: awareness of the stimulus occurs in the brain.
  • 3. Figure 1 Sensory reception
  • 6. Figure 2 Amplification Amplification is the process through which a signal is strengthened; often involves signal transduction pathways.
  • 9. Sensory perception Integration: several weak stimuli are added into one large perceived stimulus. Occurs at several steps: • During signal transduction, separate stimuli are added together to generate an action potential. • During transmission, several rapid action potentials are integrated into one. • In the CNS, signals from multiple sensory cells are integrated into one signal.
  • 10. Sensory adaptation Sensitivity of sensory receptors changes in response to constant stimulation • Enables an animal to adjust to changing environmental conditions. • Enables an animal to ignore constant stimuli that might otherwise be distracting.
  • 11. Types of sensory receptor • Mechanoreceptors • Chemoreceptors • Electromagnetic receptors • Thermoreceptors • Nociceptors (pain receptors)
  • 12. Mechanoreceptors • Respond to mechanical stimulation, such as pressure and sound. • Responsible for senses of touch and hearing • Ion channels open or close in response to deformation or movement.
  • 13. Figure 3 Skin mechanoreceptors Sensory receptors in the skin and surrounding hair follicles respond to pressure.
  • 14. Figure 4 Lateral line system Used to sense movement of water.
  • 17. Chemoreceptors Bind chemicals, responsible for senses of taste and smell. Olfaction: sense of smell, involves detection of airborne chemicals called odorants. Gustation: sense of taste, involves detection of dissolved chemicals called tastants. Aquatic animals do not have distinct senses of taste and smell.
  • 18. Figure 5 Pheromones for navigation Lampreys detect pheromones secreted by the larvae of their species to navigate to breeding sites. (a) Jacana/Science Source. (b) Gary Meszaros/Science Source.
  • 19. Electromechanical receptors • Detect electromagnetic energy such as light, electricity, and magnetism • Photoreceptors detect light and are responsible for vision. Visual organs: Eyespots (planaria): sense light and dark Compound eyes (insects): detect motion. Single-lens eyes (vertebrates and some invertebrates): focus image.
  • 20. Figure 6 Photoreception Planaria move away from light sources using photosensitive eyespots.
  • 21. Figure 7 Electromagnetic reception Monarch butterflies use magnetite to orient themselves with respect to Earth’s magnetic field and navigate during winter migrations. Courtesy of Gene Nieminen/USFWS.
  • 23. Nociceptors (pain receptors) • Detect injurious stimuli such as extreme heat, pressure, and dangerous chemicals. • In humans, many nociceptors are naked dendrites of other types of receptors; thermoreceptors, mechanoreceptors, and chemoreceptors can act as nociceptors.
  • 24. MO Figure Auditory and Balance System Courtesy of B. Peterson/USFWS.
  • 25. Figure 1 The Auditory System
  • 26. Figure 2 The Cochlea Primary site of auditory sense reception. Contains the fluid-filled vestibular and tympanic canals. Vibration of the basilar membrane causes cilia on hair cells to bend. Signals are transmitted to the brain through the auditory nerve.
  • 30. Figure 3 Hair cells Bend back and forth in response to fluid movements from sound waves. The bending movements are translated into neural signals that are transmitted to the brain. © 2004 Nature Publishing Group Modified from Frolenkov, G. I., et al., Genetic insights into the morphogenesis of inner ear hair cells. Nature Reviews Genetics 5, 489–498 (2004) doi:10.1038/nrg1377. Used with permission.
  • 31. Figure 4 Mechanism of hearing
  • 35. Figure 5 Mechanism of hearing The basilar membrane gets thinner and more flexible toward the center of the cochlea.
  • 36. Figure 5a Mechanism of hearing
  • 37. Figure 5b Mechanism of hearing The basilar membrane gets thinner and more flexible toward the center of the cochlea.
  • 38. Figure 6 The balance systems
  • 42. Figure 7 Semicircular canals © 2007 Nature Publishing Group Sanlaville D. & Verloes, A. CHARGE syndrome: an update. European Journal of Human Genetics 15, 389–399 (2007) doi:10.1038/sj.ejhg.5201778. Used with permission. Clearly visible in normal newborns (left) and missing in CHARGE affected newborns (right).
  • 43. MO Figure Vision Courtesy of Gary M. Stolz/USFWS.
  • 44. Figure 1 Eyespots Planaria have primitive eyespots with photosensitive tissue. Eric V. Grave/Science Source.
  • 45. Figure 2 Compound eyes Thomas Shahan/Science Source. Contain many ommatidia, each with its own lens. Highly sensitive to motion.
  • 46. Figure 3 Eye and retina anatomy
  • 49. Figure 4 Microscope vs. eyes Both have lenses that refract light. Both can focus an image. Both have an iris that adjusts light levels.
  • 52. Figure 5 Myopia, hyperopia, and astigmatism Abnormal curvature of the lens or cornea results in light focusing incorrectly on the retina.
  • 56. Figure 6 Retinal neurons Several types of neurons in the retina communicate with each other to refine, sharpen, and process visual stimuli. These include bipolar cells (green), rod photoreceptors (red/purple), cones, amacrine cells, ganglion cells, and others. © 2010 Nature Publishing Group Markus, A. Speedy rod signaling. Nature Neuroscience 13, 410 (2010) doi:10.1038/nn0410-410. Used with permission.
  • 57. Figure 7 Visual processing Although images are inverted at the retina, the visual cortex of the brain reorients the images properly.
  • 58. MO Figure Taste and Smell Picture Partners/Science Source.
  • 59. Figure 1 Chemoreceptors Robert Noonan/Science Source. Insects have olfactory receptors that are typically found on their antennae. Gustatory receptors can be found on mouthparts and legs.
  • 60. Figure 2 Taste buds Associated with papillae of the tongue. Contain cells that detect sweet, salty, bitter, sour, and umami (savory) tastes.
  • 65. Figure 4 Olfaction Greg Dimijian/Science Source. Skunks use odorants for defense.
  • 66. Figure 5 The olfactory pathway Binding of odorants to chemoreceptor neurons triggers action potentials that are transmitted to the olfactory bulb and brain.

Editor's Notes

  1. This interactive can be found as a separate file in your downloaded folder. This slide is a placeholder only. The image is a screen shot taken from the digital book.