Submit Search
Upload
08 lecture Intro to Metabolism
•
Download as PPTX, PDF
•
8 likes
•
3,776 views
D
deskam2
Follow
GIllette College BIOL 1010-30 Fall 2014 Lec 8 Intro to Metabolism
Read less
Read more
Science
Slideshow view
Report
Share
Slideshow view
Report
Share
1 of 77
Download now
Recommended
Biology in Focus - Chapter 6
Biology in Focus - Chapter 6
mpattani
Biology in Focus Chapter 5
Biology in Focus Chapter 5
mpattani
Biology in Focus - Chapter 8
Biology in Focus - Chapter 8
mpattani
10 lecture Gillette College BIOL 1010-30
10 lecture Gillette College BIOL 1010-30
deskam2
06 A Metabolism Energy Life Campbell
06 A Metabolism Energy Life Campbell
hursmi
Biology in Focus - Chapter 9
Biology in Focus - Chapter 9
mpattani
Biology in Focus Chapter 1
Biology in Focus Chapter 1
mpattani
Biology in Focus - Chapter 7
Biology in Focus - Chapter 7
mpattani
Recommended
Biology in Focus - Chapter 6
Biology in Focus - Chapter 6
mpattani
Biology in Focus Chapter 5
Biology in Focus Chapter 5
mpattani
Biology in Focus - Chapter 8
Biology in Focus - Chapter 8
mpattani
10 lecture Gillette College BIOL 1010-30
10 lecture Gillette College BIOL 1010-30
deskam2
06 A Metabolism Energy Life Campbell
06 A Metabolism Energy Life Campbell
hursmi
Biology in Focus - Chapter 9
Biology in Focus - Chapter 9
mpattani
Biology in Focus Chapter 1
Biology in Focus Chapter 1
mpattani
Biology in Focus - Chapter 7
Biology in Focus - Chapter 7
mpattani
Biology in Focus Chapter 4
Biology in Focus Chapter 4
mpattani
Biology in Focus Chapter 2
Biology in Focus Chapter 2
mpattani
Biology in Focus - Chapter 13
Biology in Focus - Chapter 13
mpattani
Biology in Focus - Chapter 31
Biology in Focus - Chapter 31
mpattani
Ch 8: Introduction to Metabolism
Ch 8: Introduction to Metabolism
veneethmathew
Biology in Focus - Chapter 11
Biology in Focus - Chapter 11
mpattani
Ch 10: Photosynthesis
Ch 10: Photosynthesis
veneethmathew
Biology in Focus - Chapter 37
Biology in Focus - Chapter 37
mpattani
Biology in Focus Chapter 3
Biology in Focus Chapter 3
mpattani
Ch 4: Carbon and Diversity
Ch 4: Carbon and Diversity
veneethmathew
Biology in Focus - Chapter 16
Biology in Focus - Chapter 16
mpattani
09 lecture BIOL 1010-30 Gillette College
09 lecture BIOL 1010-30 Gillette College
deskam2
Biology in Focus - Chapter 35
Biology in Focus - Chapter 35
mpattani
Ch 6: A Tour of the Cell
Ch 6: A Tour of the Cell
veneethmathew
Ch 3: Water and Life
Ch 3: Water and Life
veneethmathew
07 lecture BIOL 1010-30 Gillette College
07 lecture BIOL 1010-30 Gillette College
deskam2
Chapter 9: Respiration
Chapter 9: Respiration
Angel Vega
Ch 9: Cell Respiration and Fermentation
Ch 9: Cell Respiration and Fermentation
veneethmathew
Ch 11: Cell Communication
Ch 11: Cell Communication
veneethmathew
Tiếng Anh chuyên ngành Sinh học [04 lecture presentation]
Tiếng Anh chuyên ngành Sinh học [04 lecture presentation]
Tài liệu sinh học
Chapter 8(1)
Chapter 8(1)
mrsteven
Ch 09 Muslces and Muslce Tissue Gillette College
Ch 09 Muslces and Muslce Tissue Gillette College
deskam2
More Related Content
What's hot
Biology in Focus Chapter 4
Biology in Focus Chapter 4
mpattani
Biology in Focus Chapter 2
Biology in Focus Chapter 2
mpattani
Biology in Focus - Chapter 13
Biology in Focus - Chapter 13
mpattani
Biology in Focus - Chapter 31
Biology in Focus - Chapter 31
mpattani
Ch 8: Introduction to Metabolism
Ch 8: Introduction to Metabolism
veneethmathew
Biology in Focus - Chapter 11
Biology in Focus - Chapter 11
mpattani
Ch 10: Photosynthesis
Ch 10: Photosynthesis
veneethmathew
Biology in Focus - Chapter 37
Biology in Focus - Chapter 37
mpattani
Biology in Focus Chapter 3
Biology in Focus Chapter 3
mpattani
Ch 4: Carbon and Diversity
Ch 4: Carbon and Diversity
veneethmathew
Biology in Focus - Chapter 16
Biology in Focus - Chapter 16
mpattani
09 lecture BIOL 1010-30 Gillette College
09 lecture BIOL 1010-30 Gillette College
deskam2
Biology in Focus - Chapter 35
Biology in Focus - Chapter 35
mpattani
Ch 6: A Tour of the Cell
Ch 6: A Tour of the Cell
veneethmathew
Ch 3: Water and Life
Ch 3: Water and Life
veneethmathew
07 lecture BIOL 1010-30 Gillette College
07 lecture BIOL 1010-30 Gillette College
deskam2
Chapter 9: Respiration
Chapter 9: Respiration
Angel Vega
Ch 9: Cell Respiration and Fermentation
Ch 9: Cell Respiration and Fermentation
veneethmathew
Ch 11: Cell Communication
Ch 11: Cell Communication
veneethmathew
Tiếng Anh chuyên ngành Sinh học [04 lecture presentation]
Tiếng Anh chuyên ngành Sinh học [04 lecture presentation]
Tài liệu sinh học
What's hot
(20)
Biology in Focus Chapter 4
Biology in Focus Chapter 4
Biology in Focus Chapter 2
Biology in Focus Chapter 2
Biology in Focus - Chapter 13
Biology in Focus - Chapter 13
Biology in Focus - Chapter 31
Biology in Focus - Chapter 31
Ch 8: Introduction to Metabolism
Ch 8: Introduction to Metabolism
Biology in Focus - Chapter 11
Biology in Focus - Chapter 11
Ch 10: Photosynthesis
Ch 10: Photosynthesis
Biology in Focus - Chapter 37
Biology in Focus - Chapter 37
Biology in Focus Chapter 3
Biology in Focus Chapter 3
Ch 4: Carbon and Diversity
Ch 4: Carbon and Diversity
Biology in Focus - Chapter 16
Biology in Focus - Chapter 16
09 lecture BIOL 1010-30 Gillette College
09 lecture BIOL 1010-30 Gillette College
Biology in Focus - Chapter 35
Biology in Focus - Chapter 35
Ch 6: A Tour of the Cell
Ch 6: A Tour of the Cell
Ch 3: Water and Life
Ch 3: Water and Life
07 lecture BIOL 1010-30 Gillette College
07 lecture BIOL 1010-30 Gillette College
Chapter 9: Respiration
Chapter 9: Respiration
Ch 9: Cell Respiration and Fermentation
Ch 9: Cell Respiration and Fermentation
Ch 11: Cell Communication
Ch 11: Cell Communication
Tiếng Anh chuyên ngành Sinh học [04 lecture presentation]
Tiếng Anh chuyên ngành Sinh học [04 lecture presentation]
Viewers also liked
Chapter 8(1)
Chapter 8(1)
mrsteven
Ch 09 Muslces and Muslce Tissue Gillette College
Ch 09 Muslces and Muslce Tissue Gillette College
deskam2
Enzymes cell-biology-lecture-power point-vcbc
Enzymes cell-biology-lecture-power point-vcbc
marsaalnil
Chapter 16 Obj 01
Chapter 16 Obj 01
jessy731
Phys 02 14a
Phys 02 14a
jessy731
7,integration of metabolism
7,integration of metabolism
Thumz Industries (MBBS)
Signal trasduction
Signal trasduction
Mahendrakar M D
12 lecture Gillette College BIOL 1010-30
12 lecture Gillette College BIOL 1010-30
deskam2
Chapter 8 notes
Chapter 8 notes
petersbiology
Week 9
Week 9
kristenw3
Sandipayan_enzyme inhibition_seminar
Sandipayan_enzyme inhibition_seminar
SANDIPAYAN DUTTA
Mind maps biochemistry fuel metabolism and nutrition
Mind maps biochemistry fuel metabolism and nutrition
Nicolas Lévy
enzymes
enzymes
Tahsin Noor
Pulse Genomics Comes of Age
Pulse Genomics Comes of Age
ICARDA
Cells And Enzymes
Cells And Enzymes
rossbiology
Ecology2 Complete
Ecology2 Complete
medik.cz
B.sc. biochemistry sem 1 introduction to biochemistry unit 4 metabolism and b...
B.sc. biochemistry sem 1 introduction to biochemistry unit 4 metabolism and b...
Rai University
6 enzymes
6 enzymes
Siham Gritly
gjenet dhe semundjet gjenetike
gjenet dhe semundjet gjenetike
Dajana Gjini
Enzymes Biochemistry
Enzymes Biochemistry
Kalaivanisathishr
Viewers also liked
(20)
Chapter 8(1)
Chapter 8(1)
Ch 09 Muslces and Muslce Tissue Gillette College
Ch 09 Muslces and Muslce Tissue Gillette College
Enzymes cell-biology-lecture-power point-vcbc
Enzymes cell-biology-lecture-power point-vcbc
Chapter 16 Obj 01
Chapter 16 Obj 01
Phys 02 14a
Phys 02 14a
7,integration of metabolism
7,integration of metabolism
Signal trasduction
Signal trasduction
12 lecture Gillette College BIOL 1010-30
12 lecture Gillette College BIOL 1010-30
Chapter 8 notes
Chapter 8 notes
Week 9
Week 9
Sandipayan_enzyme inhibition_seminar
Sandipayan_enzyme inhibition_seminar
Mind maps biochemistry fuel metabolism and nutrition
Mind maps biochemistry fuel metabolism and nutrition
enzymes
enzymes
Pulse Genomics Comes of Age
Pulse Genomics Comes of Age
Cells And Enzymes
Cells And Enzymes
Ecology2 Complete
Ecology2 Complete
B.sc. biochemistry sem 1 introduction to biochemistry unit 4 metabolism and b...
B.sc. biochemistry sem 1 introduction to biochemistry unit 4 metabolism and b...
6 enzymes
6 enzymes
gjenet dhe semundjet gjenetike
gjenet dhe semundjet gjenetike
Enzymes Biochemistry
Enzymes Biochemistry
Similar to 08 lecture Intro to Metabolism
06lecturepresentation 151001180656-lva1-app6892
06lecturepresentation 151001180656-lva1-app6892
Cleophas Rwemera
08anintroductiontometabolism 130311053344-phpapp01
08anintroductiontometabolism 130311053344-phpapp01
Cleophas Rwemera
chap8ppt (1).ppt
chap8ppt (1).ppt
LianneGraceParreas
Passive vs. Active transport.mp4.downloadPassive vs. Active tra
Passive vs. Active transport.mp4.downloadPassive vs. Active tra
twilacrt6k5
Chapter 7Energy and Metabolism© Cengage Learning 2015.docx
Chapter 7Energy and Metabolism© Cengage Learning 2015.docx
mccormicknadine86
Passive vs. Active transport.mp4.downloadPassive vs. Active tra.docx
Passive vs. Active transport.mp4.downloadPassive vs. Active tra.docx
ssuser562afc1
chapter8.ppt
chapter8.ppt
WushuTalkingPoint
null.pptx
null.pptx
AsadBhai3
Lecture-6 Energy, Enzymes, and Metabolism.ppt
Lecture-6 Energy, Enzymes, and Metabolism.ppt
MuhammadRizwan863722
08 an introduction to metabolism
08 an introduction to metabolism
kindarspirit
Ch06 lecture
Ch06 lecture
Roy Withers
An introduction to metabolism
An introduction to metabolism
abdulhussien aljebory
forjeffpark
forjeffpark
guestb836271
bioenergetics.pptx
bioenergetics.pptx
ManoharKumar81
Bioenergetics by lecture Biswanath.pdf
Bioenergetics by lecture Biswanath.pdf
College of pharmaceutical sciences
Chapter 8 metabolism
Chapter 8 metabolism
Angel Vega
Chapter8 metabolism-151125142235-lva1-app6892
Chapter8 metabolism-151125142235-lva1-app6892
Cleophas Rwemera
Chapter8 metabolism-151125142235-lva1-app6892
Chapter8 metabolism-151125142235-lva1-app6892
Cleophas Rwemera
Bioenergetics
Bioenergetics
Mohit Roy
08 metabolism text
08 metabolism text
Andrew McCaskill
Similar to 08 lecture Intro to Metabolism
(20)
06lecturepresentation 151001180656-lva1-app6892
06lecturepresentation 151001180656-lva1-app6892
08anintroductiontometabolism 130311053344-phpapp01
08anintroductiontometabolism 130311053344-phpapp01
chap8ppt (1).ppt
chap8ppt (1).ppt
Passive vs. Active transport.mp4.downloadPassive vs. Active tra
Passive vs. Active transport.mp4.downloadPassive vs. Active tra
Chapter 7Energy and Metabolism© Cengage Learning 2015.docx
Chapter 7Energy and Metabolism© Cengage Learning 2015.docx
Passive vs. Active transport.mp4.downloadPassive vs. Active tra.docx
Passive vs. Active transport.mp4.downloadPassive vs. Active tra.docx
chapter8.ppt
chapter8.ppt
null.pptx
null.pptx
Lecture-6 Energy, Enzymes, and Metabolism.ppt
Lecture-6 Energy, Enzymes, and Metabolism.ppt
08 an introduction to metabolism
08 an introduction to metabolism
Ch06 lecture
Ch06 lecture
An introduction to metabolism
An introduction to metabolism
forjeffpark
forjeffpark
bioenergetics.pptx
bioenergetics.pptx
Bioenergetics by lecture Biswanath.pdf
Bioenergetics by lecture Biswanath.pdf
Chapter 8 metabolism
Chapter 8 metabolism
Chapter8 metabolism-151125142235-lva1-app6892
Chapter8 metabolism-151125142235-lva1-app6892
Chapter8 metabolism-151125142235-lva1-app6892
Chapter8 metabolism-151125142235-lva1-app6892
Bioenergetics
Bioenergetics
08 metabolism text
08 metabolism text
More from deskam2
06 Lecture BIOL 1010-30 Gillette College
06 Lecture BIOL 1010-30 Gillette College
deskam2
05 Lecture BIOL 1010-30 Gillette College
05 Lecture BIOL 1010-30 Gillette College
deskam2
03 Lecture BIOL 1010-30 Gillette College
03 Lecture BIOL 1010-30 Gillette College
deskam2
02 Lecture BIOL 1010-30 Gillette College
02 Lecture BIOL 1010-30 Gillette College
deskam2
01 Lecture BIOL 1010 30 Gillette College
01 Lecture BIOL 1010 30 Gillette College
deskam2
23 lecture BIOL 1010-30 Gillette College
23 lecture BIOL 1010-30 Gillette College
deskam2
22 lecture BIOL 1010-30 Gillette College
22 lecture BIOL 1010-30 Gillette College
deskam2
17 Lecture BIOL 1010-30 Gillette College
17 Lecture BIOL 1010-30 Gillette College
deskam2
15 Lecture BIOL 1030-30 Gillette College
15 Lecture BIOL 1030-30 Gillette College
deskam2
14 lecture BIOL 1010-30 Gillette College
14 lecture BIOL 1010-30 Gillette College
deskam2
13 Lecture BIOL 1030-30 Gillette College
13 Lecture BIOL 1030-30 Gillette College
deskam2
More from deskam2
(11)
06 Lecture BIOL 1010-30 Gillette College
06 Lecture BIOL 1010-30 Gillette College
05 Lecture BIOL 1010-30 Gillette College
05 Lecture BIOL 1010-30 Gillette College
03 Lecture BIOL 1010-30 Gillette College
03 Lecture BIOL 1010-30 Gillette College
02 Lecture BIOL 1010-30 Gillette College
02 Lecture BIOL 1010-30 Gillette College
01 Lecture BIOL 1010 30 Gillette College
01 Lecture BIOL 1010 30 Gillette College
23 lecture BIOL 1010-30 Gillette College
23 lecture BIOL 1010-30 Gillette College
22 lecture BIOL 1010-30 Gillette College
22 lecture BIOL 1010-30 Gillette College
17 Lecture BIOL 1010-30 Gillette College
17 Lecture BIOL 1010-30 Gillette College
15 Lecture BIOL 1030-30 Gillette College
15 Lecture BIOL 1030-30 Gillette College
14 lecture BIOL 1010-30 Gillette College
14 lecture BIOL 1010-30 Gillette College
13 Lecture BIOL 1030-30 Gillette College
13 Lecture BIOL 1030-30 Gillette College
Recently uploaded
STOPPED FLOW METHOD & APPLICATION MURUGAVENI B.pptx
STOPPED FLOW METHOD & APPLICATION MURUGAVENI B.pptx
Murugaveni B
User Guide: Pulsar™ Weather Station (Columbia Weather Systems)
User Guide: Pulsar™ Weather Station (Columbia Weather Systems)
Columbia Weather Systems
REVISTA DE BIOLOGIA E CIÊNCIAS DA TERRA ISSN 1519-5228 - Artigo_Bioterra_V24_...
REVISTA DE BIOLOGIA E CIÊNCIAS DA TERRA ISSN 1519-5228 - Artigo_Bioterra_V24_...
Universidade Federal de Sergipe - UFS
REVISTA DE BIOLOGIA E CIÊNCIAS DA TERRA ISSN 1519-5228 - Artigo_Bioterra_V24_...
REVISTA DE BIOLOGIA E CIÊNCIAS DA TERRA ISSN 1519-5228 - Artigo_Bioterra_V24_...
Universidade Federal de Sergipe - UFS
Hot Sexy call girls in Moti Nagar,🔝 9953056974 🔝 escort Service
Hot Sexy call girls in Moti Nagar,🔝 9953056974 🔝 escort Service
9953056974 Low Rate Call Girls In Saket, Delhi NCR
Pests of Blackgram, greengram, cowpea_Dr.UPR.pdf
Pests of Blackgram, greengram, cowpea_Dr.UPR.pdf
PirithiRaju
Dubai Calls Girl Lisa O525547819 Lexi Call Girls In Dubai
Dubai Calls Girl Lisa O525547819 Lexi Call Girls In Dubai
kojalkojal131
Pests of safflower_Binomics_Identification_Dr.UPR.pdf
Pests of safflower_Binomics_Identification_Dr.UPR.pdf
PirithiRaju
Pests of Bengal gram_Identification_Dr.UPR.pdf
Pests of Bengal gram_Identification_Dr.UPR.pdf
PirithiRaju
Four Spheres of the Earth Presentation.ppt
Four Spheres of the Earth Presentation.ppt
JoemSTuliba
Environmental Biotechnology Topic:- Microbial Biosensor
Environmental Biotechnology Topic:- Microbial Biosensor
sonawaneprad
Behavioral Disorder: Schizophrenia & it's Case Study.pdf
Behavioral Disorder: Schizophrenia & it's Case Study.pdf
SELF-EXPLANATORY
Good agricultural practices 3rd year bpharm. herbal drug technology .pptx
Good agricultural practices 3rd year bpharm. herbal drug technology .pptx
SimeonChristian
BIOETHICS IN RECOMBINANT DNA TECHNOLOGY.
BIOETHICS IN RECOMBINANT DNA TECHNOLOGY.
PraveenaKalaiselvan1
Fertilization: Sperm and the egg—collectively called the gametes—fuse togethe...
Fertilization: Sperm and the egg—collectively called the gametes—fuse togethe...
D. B. S. College Kanpur
OECD bibliometric indicators: Selected highlights, April 2024
OECD bibliometric indicators: Selected highlights, April 2024
innovationoecd
Call Girls in Majnu Ka Tilla Delhi 🔝9711014705🔝 Genuine
Call Girls in Majnu Ka Tilla Delhi 🔝9711014705🔝 Genuine
thapagita
LIGHT-PHENOMENA-BY-CABUALDIONALDOPANOGANCADIENTE-CONDEZA (1).pptx
LIGHT-PHENOMENA-BY-CABUALDIONALDOPANOGANCADIENTE-CONDEZA (1).pptx
malonesandreagweneth
Speech, hearing, noise, intelligibility.pptx
Speech, hearing, noise, intelligibility.pptx
priyankatabhane
Harmful and Useful Microorganisms Presentation
Harmful and Useful Microorganisms Presentation
tahreemzahra82
Recently uploaded
(20)
STOPPED FLOW METHOD & APPLICATION MURUGAVENI B.pptx
STOPPED FLOW METHOD & APPLICATION MURUGAVENI B.pptx
User Guide: Pulsar™ Weather Station (Columbia Weather Systems)
User Guide: Pulsar™ Weather Station (Columbia Weather Systems)
REVISTA DE BIOLOGIA E CIÊNCIAS DA TERRA ISSN 1519-5228 - Artigo_Bioterra_V24_...
REVISTA DE BIOLOGIA E CIÊNCIAS DA TERRA ISSN 1519-5228 - Artigo_Bioterra_V24_...
REVISTA DE BIOLOGIA E CIÊNCIAS DA TERRA ISSN 1519-5228 - Artigo_Bioterra_V24_...
REVISTA DE BIOLOGIA E CIÊNCIAS DA TERRA ISSN 1519-5228 - Artigo_Bioterra_V24_...
Hot Sexy call girls in Moti Nagar,🔝 9953056974 🔝 escort Service
Hot Sexy call girls in Moti Nagar,🔝 9953056974 🔝 escort Service
Pests of Blackgram, greengram, cowpea_Dr.UPR.pdf
Pests of Blackgram, greengram, cowpea_Dr.UPR.pdf
Dubai Calls Girl Lisa O525547819 Lexi Call Girls In Dubai
Dubai Calls Girl Lisa O525547819 Lexi Call Girls In Dubai
Pests of safflower_Binomics_Identification_Dr.UPR.pdf
Pests of safflower_Binomics_Identification_Dr.UPR.pdf
Pests of Bengal gram_Identification_Dr.UPR.pdf
Pests of Bengal gram_Identification_Dr.UPR.pdf
Four Spheres of the Earth Presentation.ppt
Four Spheres of the Earth Presentation.ppt
Environmental Biotechnology Topic:- Microbial Biosensor
Environmental Biotechnology Topic:- Microbial Biosensor
Behavioral Disorder: Schizophrenia & it's Case Study.pdf
Behavioral Disorder: Schizophrenia & it's Case Study.pdf
Good agricultural practices 3rd year bpharm. herbal drug technology .pptx
Good agricultural practices 3rd year bpharm. herbal drug technology .pptx
BIOETHICS IN RECOMBINANT DNA TECHNOLOGY.
BIOETHICS IN RECOMBINANT DNA TECHNOLOGY.
Fertilization: Sperm and the egg—collectively called the gametes—fuse togethe...
Fertilization: Sperm and the egg—collectively called the gametes—fuse togethe...
OECD bibliometric indicators: Selected highlights, April 2024
OECD bibliometric indicators: Selected highlights, April 2024
Call Girls in Majnu Ka Tilla Delhi 🔝9711014705🔝 Genuine
Call Girls in Majnu Ka Tilla Delhi 🔝9711014705🔝 Genuine
LIGHT-PHENOMENA-BY-CABUALDIONALDOPANOGANCADIENTE-CONDEZA (1).pptx
LIGHT-PHENOMENA-BY-CABUALDIONALDOPANOGANCADIENTE-CONDEZA (1).pptx
Speech, hearing, noise, intelligibility.pptx
Speech, hearing, noise, intelligibility.pptx
Harmful and Useful Microorganisms Presentation
Harmful and Useful Microorganisms Presentation
08 lecture Intro to Metabolism
1.
CAMPBELL BIOLOGY Reece
• Urry • Cain •Wasserman • Minorsky • Jackson © 2014 Pearson Education, Inc. TENTH EDITION 8 An Introduction to Metabolism Lecture Presentation by Nicole Tunbridge and Kathleen Fitzpatrick
2.
The Energy of
Life The living cell is a miniature chemical factory where thousands of reactions occur The cell extracts energy stored in sugars and other fuels and applies energy to perform work Some organisms even convert energy to light, as in bioluminescence © 2014 Pearson Education, Inc.
3.
Concept 8.1: An
organism’s metabolism transforms matter and energy, subject to the laws of thermodynamics Metabolism is the totality of an organism’s chemical reactions Metabolism is an emergent property of life that arises from orderly interactions between molecules © 2014 Pearson Education, Inc.
4.
Organization of the
Chemistry of Life into Metabolic Pathways A metabolic pathway begins with a specific molecule and ends with a product Each step is catalyzed by a specific enzyme © 2014 Pearson Education, Inc.
5.
Figure 8.UN01 Enzyme
1 Enzyme 2 Enzyme 3 A B C D Reaction 1 Reaction 2 Reaction 3 Starting Product molecule © 2014 Pearson Education, Inc.
6.
Catabolic pathways
release energy by breaking down complex molecules into simpler compounds Cellular respiration, the breakdown of glucose in the presence of oxygen, is an example of a pathway of catabolism © 2014 Pearson Education, Inc.
7.
Anabolic pathways
consume energy to build complex molecules from simpler ones The synthesis of protein from amino acids is an example of anabolism Bioenergetics is the study of how energy flows through living organisms © 2014 Pearson Education, Inc.
8.
Forms of Energy
Energy is the capacity to cause change Energy exists in various forms, some of which can perform work © 2014 Pearson Education, Inc.
9.
Kinetic energy
is energy associated with motion Heat (thermal energy) is kinetic energy associated with random movement of atoms or molecules Potential energy is energy that matter possesses because of its location or structure Chemical energy is potential energy available for release in a chemical reaction Energy can be converted from one form to another © 2014 Pearson Education, Inc.
10.
Figure 8.2 A
diver has more potential energy on the platform than in the water. © 2014 Pearson Education, Inc. Diving converts potential energy to kinetic energy. A diver has less potential energy in the water than on the platform. Climbing up converts the kinetic energy of muscle movement to potential energy.
11.
The Laws of
Energy Transformation Thermodynamics is the study of energy transformations An isolated system, such as that approximated by liquid in a thermos, is unable to exchange energy or matter with its surroundings In an open system, energy and matter can be transferred between the system and its surroundings Organisms are open systems © 2014 Pearson Education, Inc.
12.
The First Law
of Thermodynamics According to the first law of thermodynamics, the energy of the universe is constant Energy can be transferred and transformed, but it cannot be created or destroyed The first law is also called the principle of conservation of energy © 2014 Pearson Education, Inc.
13.
The Second Law
of Thermodynamics During every energy transfer or transformation, some energy is unusable, and is often lost as heat According to the second law of thermodynamics Every energy transfer or transformation increases the entropy (disorder) of the universe © 2014 Pearson Education, Inc.
14.
Figure 8.3 (a)
First law of thermo- (b) dynamics © 2014 Pearson Education, Inc. Second law of thermodynamics Chemical energy Heat CO2 H2O
15.
Living cells
unavoidably convert organized forms of energy to heat Spontaneous processes occur without energy input; they can happen quickly or slowly For a process to occur without energy input, it must increase the entropy of the universe © 2014 Pearson Education, Inc.
16.
Biological Order and
Disorder Cells create ordered structures from less ordered materials Organisms also replace ordered forms of matter and energy with less ordered forms Energy flows into an ecosystem in the form of light and exits in the form of heat © 2014 Pearson Education, Inc.
17.
The evolution
of more complex organisms does not violate the second law of thermodynamics Entropy (disorder) may decrease in an organism, but the universe’s total entropy increases © 2014 Pearson Education, Inc.
18.
Concept 8.2: The
free-energy change of a reaction tells us whether or not the reaction occurs spontaneously Biologists want to know which reactions occur spontaneously and which require input of energy To do so, they need to determine energy changes that occur in chemical reactions © 2014 Pearson Education, Inc.
19.
Free-Energy Change, G
A living system’s free energy is energy that can do work when temperature and pressure are uniform, as in a living cell © 2014 Pearson Education, Inc.
20.
The change
in free energy (ΔG) during a process is related to the change in enthalpy, or change in total energy (ΔH), change in entropy (ΔS), and temperature in Kelvin units (T) © 2014 Pearson Education, Inc. ΔG = ΔH - TΔS Only processes with a negative ΔG are spontaneous Spontaneous processes can be harnessed to perform work
21.
Free Energy, Stability,
and Equilibrium Free energy is a measure of a system’s instability, its tendency to change to a more stable state During a spontaneous change, free energy decreases and the stability of a system increases Equilibrium is a state of maximum stability A process is spontaneous and can perform work only when it is moving toward equilibrium © 2014 Pearson Education, Inc.
22.
Figure 8.5 •
More free energy (higher G) • Less stable • Greater work capacity In a spontaneous change • • Less free energy (lower G) • More stable • Less work capacity © 2014 Pearson Education, Inc. (a) Gravitational motion (b) Diffusion (c) Chemical reaction The free energy of the system decreases (ΔG < 0) The system becomes more stable The released free energy can be harnessed to do work • •
23.
Figure 8.5a ©
2014 Pearson Education, Inc. • More free energy (higher G) • Less stable • Greater work capacity In a spontaneous change • The free energy of the system decreases (ΔG < 0) The system becomes more stable The released free energy can be harnessed to do work • • • Less free energy (lower G) • More stable • Less work capacity
24.
Figure 8.5b (a)
Gravitational motion (b) Diffusion (c) Chemical reaction © 2014 Pearson Education, Inc.
25.
Free Energy and
Metabolism The concept of free energy can be applied to the chemistry of life’s processes © 2014 Pearson Education, Inc.
26.
Exergonic and Endergonic
Reactions in Metabolism An exergonic reaction proceeds with a net release of free energy and is spontaneous An endergonic reaction absorbs free energy from its surroundings and is nonspontaneous © 2014 Pearson Education, Inc.
27.
Figure 8.6 ©
2014 Pearson Education, Inc. Exergonic reaction: energy released, spontaneous Products Endergonic reaction: energy required, nonspontaneous (a) Free energy Free energy (b) Reactants Reactants Energy Energy Products Amount of energy released (ΔG < 0) Amount of energy required (ΔG > 0) Progress of the reaction Progress of the reaction
28.
Equilibrium and Metabolism
Reactions in a closed system eventually reach equilibrium and then do no work © 2014 Pearson Education, Inc.
29.
Figure 8.7 ©
2014 Pearson Education, Inc. ΔG < 0 ΔG = 0
30.
Cells are
not in equilibrium; they are open systems experiencing a constant flow of materials A defining feature of life is that metabolism is never at equilibrium A catabolic pathway in a cell releases free energy in a series of reactions © 2014 Pearson Education, Inc.
31.
Figure 8.8 (a)
An open hydro-electric © 2014 Pearson Education, Inc. system ΔG < 0 ΔG < 0 ΔG < 0 (b) A multistep open hydroelectric system ΔG < 0
32.
Concept 8.3: ATP
powers cellular work by coupling exergonic reactions to endergonic reactions A cell does three main kinds of work Chemical Transport Mechanical To do work, cells manage energy resources by energy coupling, the use of an exergonic process to drive an endergonic one Most energy coupling in cells is mediated by ATP © 2014 Pearson Education, Inc.
33.
The Structure and
Hydrolysis of ATP ATP (adenosine triphosphate) is the cell’s energy shuttle ATP is composed of ribose (a sugar), adenine (a nitrogenous base), and three phosphate groups © 2014 Pearson Education, Inc.
34.
Figure 8.9 ©
2014 Pearson Education, Inc. (a) The structure of ATP Adenine Adenosine triphosphate (ATP) (b) The hydrolysis of ATP Ribose Triphosphate group (3 phosphate groups) Adenosine diphosphate (ADP) Energy Inorganic phosphate H2O
35.
Figure 8.9a (a)
The structure of ATP © 2014 Pearson Education, Inc. Adenine Ribose Triphosphate group (3 phosphate groups)
36.
Figure 8.9b (b)
The hydrolysis of ATP © 2014 Pearson Education, Inc. Adenosine triphosphate (ATP) Adenosine diphosphate (ADP) Energy Inorganic phosphate H2O
37.
The bonds
between the phosphate groups of ATP’s tail can be broken by hydrolysis Energy is released from ATP when the terminal phosphate bond is broken This release of energy comes from the chemical change to a state of lower free energy, not from the phosphate bonds themselves © 2014 Pearson Education, Inc.
38.
How the Hydrolysis
of ATP Performs Work The three types of cellular work (mechanical, transport, and chemical) are powered by the hydrolysis of ATP In the cell, the energy from the exergonic reaction of ATP hydrolysis can be used to drive an endergonic reaction Overall, the coupled reactions are exergonic © 2014 Pearson Education, Inc.
39.
ATP drives
endergonic reactions by phosphorylation, transferring a phosphate group to some other molecule, such as a reactant The recipient molecule is now called a phosphorylated intermediate © 2014 Pearson Education, Inc.
40.
Transport and
mechanical work in the cell are also powered by ATP hydrolysis ATP hydrolysis leads to a change in protein shape and binding ability © 2014 Pearson Education, Inc.
41.
Figure 8.11 ATP
ATP © 2014 Pearson Education, Inc. Transport protein Solute P P i Solute transported ADP P i (a) Transport work: ATP phosphorylates transport proteins. Cytoskeletal track ATP ADP P i Motor protein Protein and vesicle moved Mechanical work: ATP binds noncovalently to motor proteins and then is hydrolyzed. (b) Vesicle
42.
The Regeneration of
ATP ATP is a renewable resource that is regenerated by addition of a phosphate group to adenosine diphosphate (ADP) The energy to phosphorylate ADP comes from catabolic reactions in the cell The ATP cycle is a revolving door through which energy passes during its transfer from catabolic to anabolic pathways © 2014 Pearson Education, Inc.
43.
Figure 8.12 Energy
from catabolism (exergonic, energy-releasing processes) © 2014 Pearson Education, Inc. Energy for cellular work (endergonic energy-consuming processes) H2 ATP O ADP P i
44.
Concept 8.4: Enzymes
speed up metabolic reactions by lowering energy barriers A catalyst is a chemical agent that speeds up a reaction without being consumed by the reaction An enzyme is a catalytic protein Hydrolysis of sucrose by the enzyme sucrase is an example of an enzyme-catalyzed reaction © 2014 Pearson Education, Inc.
45.
Figure 8.UN02 Sucrose
(C12H22O11) © 2014 Pearson Education, Inc. Glucose (C6H12O6) Fructose (C6H12O6) Sucrase
46.
The Activation Energy
Barrier Every chemical reaction between molecules involves bond breaking and bond forming The initial energy needed to start a chemical reaction is called the free energy of activation, or activation energy (EA) Activation energy is often supplied in the form of thermal energy that the reactant molecules absorb from their surroundings © 2014 Pearson Education, Inc.
47.
Figure 8.13 ©
2014 Pearson Education, Inc. Transition state Reactants Products EA Progress of the reaction ΔG < O Free energy A B C D A B C D A B C D
48.
Animation: How Enzymes
Work © 2014 Pearson Education, Inc.
49.
How Enzymes Speed
Up Reactions Enzymes catalyze reactions by lowering the EA barrier Enzymes do not affect the change in free energy (ΔG); instead, they hasten reactions that would occur eventually © 2014 Pearson Education, Inc.
50.
Figure 8.14 Course
of reaction without enzyme © 2014 Pearson Education, Inc. Course of reaction with enzyme EA with enzyme is lower EA without enzyme Products Reactants Free energy ΔG is unaffected by enzyme Progress of the reaction
51.
Substrate Specificity of
Enzymes The reactant that an enzyme acts on is called the enzyme’s substrate The enzyme binds to its substrate, forming an enzyme-substrate complex The reaction catalyzed by each enzyme is very specific © 2014 Pearson Education, Inc.
52.
The active
site is the region on the enzyme where the substrate binds Induced fit of a substrate brings chemical groups of the active site into positions that enhance their ability to catalyze the reaction © 2014 Pearson Education, Inc.
53.
Figure 8.15 Substrate
Active site © 2014 Pearson Education, Inc. Enzyme Enzyme-substrate complex
54.
Catalysis in the
Enzyme’s Active Site In an enzymatic reaction, the substrate binds to the active site of the enzyme The active site can lower an EA barrier by Orienting substrates correctly Straining substrate bonds Providing a favorable microenvironment Covalently bonding to the substrate © 2014 Pearson Education, Inc.
55.
Figure 8.16-1 ©
2014 Pearson Education, Inc. Substrates enter active site. Substrates Substrates are held in active site by weak interactions. 1 2 Enzyme-substrate complex
56.
Figure 8.16-2 ©
2014 Pearson Education, Inc. 1 2 Substrates enter active site. Substrates Substrates are held in active site by weak interactions. Enzyme-substrate complex Substrates are converted to products. 3
57.
Figure 8.16-3 ©
2014 Pearson Education, Inc. 1 2 Substrates enter active site. Substrates Substrates are held in active site by weak interactions. Substrates are converted to products. Products are released. Enzyme-substrate complex Products 4 3
58.
Figure 8.16-4 ©
2014 Pearson Education, Inc. 1 2 Substrates enter active site. Substrates Substrates are held in active site by weak interactions. Substrates are converted to products. Enzyme Products are released. Enzyme-substrate complex Active site is available for new substrates. Products 5 4 3
59.
Effects of Local
Conditions on Enzyme Activity An enzyme’s activity can be affected by General environmental factors, such as temperature and pH Chemicals that specifically influence the enzyme © 2014 Pearson Education, Inc.
60.
Effects of Temperature
and pH Each enzyme has an optimal temperature in which it can function Each enzyme has an optimal pH in which it can function Optimal conditions favor the most active shape for the enzyme molecule © 2014 Pearson Education, Inc.
61.
Figure 8.17 ©
2014 Pearson Education, Inc. Optimal temperature for typical human enzyme (37C) 0 20 40 60 80 100 120 Rate of reaction Rate of reaction (a) Optimal temperature for two enzymes Optimal pH for pepsin (stomach enzyme) Optimal temperature for enzyme of thermophilic (heat-tolerant) bacteria (77C) Optimal pH for trypsin (intestinal enzyme) Temperature (C) 0 1 2 3 4 5 6 7 8 9 10 pH (b) Optimal pH for two enzymes
62.
Figure 8.17a Optimal
temperature for typical human enzyme (37C) bacteria (77C) 0 20 40 60 80 100 120 Rate of reaction © 2014 Pearson Education, Inc. Optimal temperature for enzyme of thermophilic (heat-tolerant) Temperature (C) (a) Optimal temperature for two enzymes
63.
Figure 8.17b Optimal
pH for pepsin 0 1 2 3 4 5 6 7 8 9 10 Rate of reaction © 2014 Pearson Education, Inc. (stomach enzyme) Optimal pH for trypsin (intestinal enzyme) pH (b) Optimal pH for two enzymes
64.
Cofactors Cofactors
are nonprotein enzyme helpers Cofactors may be inorganic (such as a metal in ionic form) or organic An organic cofactor is called a coenzyme Coenzymes include vitamins © 2014 Pearson Education, Inc.
65.
Enzyme Inhibitors
Competitive inhibitors bind to the active site of an enzyme, competing with the substrate Noncompetitive inhibitors bind to another part of an enzyme, causing the enzyme to change shape and making the active site less effective Examples of inhibitors include toxins, poisons, pesticides, and antibiotics © 2014 Pearson Education, Inc.
66.
Figure 8.18 (a)
Normal binding (b) Competitive inhibition (c) Noncompetitive © 2014 Pearson Education, Inc. inhibition Substrate Active site Enzyme Competitive inhibitor Noncompetitive inhibitor
67.
The Evolution of
Enzymes Enzymes are proteins encoded by genes Changes (mutations) in genes lead to changes in amino acid composition of an enzyme Altered amino acids in enzymes may result in novel enzyme activity or altered substrate specificity Under new environmental conditions a novel form of an enzyme might be favored For example, six amino acid changes improved substrate binding and breakdown in E. coli © 2014 Pearson Education, Inc.
68.
Concept 8.5: Regulation
of enzyme activity helps control metabolism Chemical chaos would result if a cell’s metabolic pathways were not tightly regulated A cell does this by switching on or off the genes that encode specific enzymes or by regulating the activity of enzymes © 2014 Pearson Education, Inc.
69.
Allosteric Regulation of
Enzymes Allosteric regulation may either inhibit or stimulate an enzyme’s activity Allosteric regulation occurs when a regulatory molecule binds to a protein at one site and affects the protein’s function at another site © 2014 Pearson Education, Inc.
70.
Allosteric Activation and
Inhibition Most allosterically regulated enzymes are made from polypeptide subunits Each enzyme has active and inactive forms The binding of an activator stabilizes the active form of the enzyme The binding of an inhibitor stabilizes the inactive form of the enzyme © 2014 Pearson Education, Inc.
71.
Figure 8.20 (a)
Allosteric activators and inhibitors (b) Cooperativity: another type Allosteric enzyme with four subunits Regulatory site (one of four) © 2014 Pearson Education, Inc. Stabilized active form Inactive form Activator Oscillation Non-functional active site Active site (one of four) Active form Substrate Stabilized active form Inhibitor Inactive form Stabilized inactive form of allosteric activation
72.
Cooperativity is
a form of allosteric regulation that can amplify enzyme activity One substrate molecule primes an enzyme to act on additional substrate molecules more readily Cooperativity is allosteric because binding by a substrate to one active site affects catalysis in a different active site © 2014 Pearson Education, Inc.
73.
Feedback Inhibition
In feedback inhibition, the end product of a metabolic pathway shuts down the pathway Feedback inhibition prevents a cell from wasting chemical resources by synthesizing more product than is needed © 2014 Pearson Education, Inc.
74.
Figure 8.21 ©
2014 Pearson Education, Inc. Active site available Isoleucine used up by cell Isoleucine binds to allosteric site. Active site no longer available; pathway is halted. Threonine in active site Enzyme 1 (threonine deaminase) Feedback inhibition Intermediate A Enzyme 2 Intermediate B Enzyme 3 Intermediate C Enzyme 4 Intermediate D Enzyme 5 End product (isoleucine)
75.
Localization of Enzymes
Within the Cell Structures within the cell help bring order to metabolic pathways Some enzymes act as structural components of membranes In eukaryotic cells, some enzymes reside in specific organelles; for example, enzymes for cellular respiration are located in mitochondria © 2014 Pearson Education, Inc.
76.
Figure 8.22 ©
2014 Pearson Education, Inc. Mitochondria The matrix contains enzymes in solution that are involved on one stage of cellular respiration. Enzymes for another stage of cellular respiration are embedded in the inner membrane 1 μm
77.
Figure 8.22a ©
2014 Pearson Education, Inc. The matrix contains enzymes in solution that are involved in one stage of cellular respiration. Enzymes for another stage of cellular respiration are embedded in the inner membrane. 1 μm
Download now