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Rani 55F
Chief complaints
• 55 year old housewife presented with
• Headache for 1 year
• Palpitations for 6 months
HOPI
• H/o headache for 1 year
• Dull aching type
• Paroxysmal in nature
• No aggravating and relieving factors
• Associated with profuse sweating.
• H/o palpitation for 6 months
• Spontaneous in onset
• Associated with shortness of breath
• No aggravating and relieving factors
• No H/o urge incontinence
• No h/o hematuria/ pyuria/calcaluria/ abdominal pain/ fever/
vomiting/ oliguria
• Patient was referred from General medicine dept
Past History
• Patient treated for PTB 9 years ago and completed 6 months of ATT
• K/C/O HTN x 5 years on T. Losartan 50 BD, T. Atenolol 50mg BD, T.
Hydrochlorthiazide 12.5 BD.
• No other comorbidities
• No past surgical history
Personal History
• Not a smoker or alcoholic
• Takes a mixed diet
• Normal bowel and bladder habits
Family History – No H/o similar complaints in the family
General Examination
• Patient is moderately built and well nourished
• Afebrile
• No pallor
• No icterus
• No pedal edema
• No generalized lymphadenopathy
• Vitals:
• BP 140/90 mm hg
• PR 74/ min
Per abdominal examination
• On inspection-
All quadrants move equally with respiration
Umblicus is in midline
Hernial orifices free.
• On palpation –
No warmth
No tenderness
No guarding , no rigidity
Bladder not palpable
• On percussion – No e/o free fluid
• On auscultation –Bowel sounds present.
Systemic Examination
• CVS-S1S2+
• RS-BAE+
• CNS-NAD
Investigations
• Urine R/E
• Albumin- nil,
• Sugar- nil,
• Deposits - 0-2 pus cells /HPF
• Urine c/s –no growth
INVESTIGATIONS
• Hb- 11.4g/dl,
• TC- 9400
• DC- 70/15/12
• PLT- 2.4 L
• Urea – 34 mg/dl
• Creatinine – 1.1mg/dl
• Na+ - 138meq/l
• K+ - 4.1meq/l
• PT- 12.9
• INR- 1.00
Investigations
• Blood cortisol- 20.51 mcg/dl (10-20mcg/dl)
• Urine metanephrines- 395.99mcg/24 hours (24 - 96mcg/24 hours)
• Urine normetanephrines- 1365.94mcg/24 hours (75 – 375mcg/24 hours)
• Plasma free metanephrines
• Normetanephrine – 289pg/ml (18-111pg/ml)
• Metanephrine – 114pg/ml (12-60pg/ml)
MRI ABDOMEN
MRI Abdomen
• Well defined T2 hyperintense lesion measuring 3.5x 2.7 cm noted in
left adrenal .There is no signal loss in the out of phase imaging,
possibly- malignancy/lipid poor adenoma.
• Patient underwent Laparoscopy assisted Left adrenalectomy on
4/10/19
• HPE - Consistent with
Pheochromocytoma
• Post op uneventful
• Hypertension was well controlled in the post operative period and
requirement of antihypertensives was reduced
CT chest
CT THORAX
• Post TB sequele with reactivation, lipid poor adenoma left adrenal
gland 3x3 cm with CT attenuation +40HU with cholelithiasis.
Pheochromocytoma Case Presentation.pptx

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Pheochromocytoma Case Presentation.pptx

  • 2. Chief complaints • 55 year old housewife presented with • Headache for 1 year • Palpitations for 6 months
  • 3. HOPI • H/o headache for 1 year • Dull aching type • Paroxysmal in nature • No aggravating and relieving factors • Associated with profuse sweating. • H/o palpitation for 6 months • Spontaneous in onset • Associated with shortness of breath • No aggravating and relieving factors
  • 4. • No H/o urge incontinence • No h/o hematuria/ pyuria/calcaluria/ abdominal pain/ fever/ vomiting/ oliguria • Patient was referred from General medicine dept
  • 5. Past History • Patient treated for PTB 9 years ago and completed 6 months of ATT • K/C/O HTN x 5 years on T. Losartan 50 BD, T. Atenolol 50mg BD, T. Hydrochlorthiazide 12.5 BD. • No other comorbidities • No past surgical history Personal History • Not a smoker or alcoholic • Takes a mixed diet • Normal bowel and bladder habits Family History – No H/o similar complaints in the family
  • 6. General Examination • Patient is moderately built and well nourished • Afebrile • No pallor • No icterus • No pedal edema • No generalized lymphadenopathy • Vitals: • BP 140/90 mm hg • PR 74/ min
  • 7. Per abdominal examination • On inspection- All quadrants move equally with respiration Umblicus is in midline Hernial orifices free. • On palpation – No warmth No tenderness No guarding , no rigidity Bladder not palpable • On percussion – No e/o free fluid • On auscultation –Bowel sounds present.
  • 9. Investigations • Urine R/E • Albumin- nil, • Sugar- nil, • Deposits - 0-2 pus cells /HPF • Urine c/s –no growth
  • 10. INVESTIGATIONS • Hb- 11.4g/dl, • TC- 9400 • DC- 70/15/12 • PLT- 2.4 L • Urea – 34 mg/dl • Creatinine – 1.1mg/dl • Na+ - 138meq/l • K+ - 4.1meq/l • PT- 12.9 • INR- 1.00
  • 11. Investigations • Blood cortisol- 20.51 mcg/dl (10-20mcg/dl) • Urine metanephrines- 395.99mcg/24 hours (24 - 96mcg/24 hours) • Urine normetanephrines- 1365.94mcg/24 hours (75 – 375mcg/24 hours) • Plasma free metanephrines • Normetanephrine – 289pg/ml (18-111pg/ml) • Metanephrine – 114pg/ml (12-60pg/ml)
  • 13.
  • 14.
  • 15.
  • 16. MRI Abdomen • Well defined T2 hyperintense lesion measuring 3.5x 2.7 cm noted in left adrenal .There is no signal loss in the out of phase imaging, possibly- malignancy/lipid poor adenoma.
  • 17. • Patient underwent Laparoscopy assisted Left adrenalectomy on 4/10/19
  • 18. • HPE - Consistent with Pheochromocytoma
  • 19. • Post op uneventful • Hypertension was well controlled in the post operative period and requirement of antihypertensives was reduced
  • 21. CT THORAX • Post TB sequele with reactivation, lipid poor adenoma left adrenal gland 3x3 cm with CT attenuation +40HU with cholelithiasis.