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2. 1948-Thomas Weller&Frederick
Robbins succeed in growing
poliovirus in live cells

3. 1955:Dr.Jonas Salk-
inactivated,injectable vaccine
Systemic immunity
No local immunity
No protection to
community.

4. 1961:Dr.Albert Sabin-live oral
vaccine
Easy to administer
Relatively cheap
Interrupt WPV
transmission
66%-herd immunity

5. 1980-OPV in UIP
1988-global goal to eradicate
polio by 2000(WHO).
zero incidence of WPV
transmission anywhere inthe
world.
Excludes VDPV(1case/1million
vaccinees)

6. 1995-IPPI
Istround-9th dec 1995&20th jan
1996.
Under 3 yrs irrespective of
immun status
87 million children
Jan 10,feb 7 2010

7.  Conducted on NID
 sudden,simultaneous,mass admn of
OPV,0-5yrs
 Mass immunisation campaigns
 2drops using dropper supplied with
vial
 Extra doses
 No min interval b/w PPI &scheduled
OPV doses

8. Nov- feb:low transmn season
Jun-sep:peak transmn-envt
sources of inf
House to house search for
missed children &vaccinating
them on next 2 days.

9. 1998
Colour monitors/labels
Circle of deep blue colour
White square,heat sensitive
material
High temp,colour changes to
blue-ineffective

13. 1988-125 endemic contries
2008-
4(India,Afghanistan,Pakistan,Nig
eria)
SEAR-India(UP&Bihar)
Kerala –last case in
Malapuram,2000

14. Poor service delivery
mechanisms
Low public awareness
Lack of comm participation
Lack of co-ordn b/w diff
working units