3. Animal Cloning
This is a list of animals that have been
cloned in alphabetical order. One
significant aspect of this list is
documenting the transition from early
concerns that animal cloning
procedures might be limited to a few
species, that cloned animals might be
physiologically abnormal, or cloning
might ...
4.
5. CC, for "CopyCat" or "Carbon
Copy"[1] (born December 22, 2001), is a
brown tabby and white domestic
shorthair and the first cloned pet. CC's
surrogate mother was a tabby, but her
genetic donor, Rainbow, was
a calico domestic shorthair. The
difference in hair coloration between
CC and Rainbow is due
to epigenetic re-programming, which
normally occurs in
a fertilised embryo before implantation.
6. As a result of the cloning process, X
inactivation occurred in the same X
chromosome in all of CC's somatic cells,
instead of the usual mosaicism that
gives calicos their distinctive coloration. CC
is genetically identical to Rainbow but
epigenetically and
thus phenotypically different. The embryo
that became CC was the only one of 87
embryos produced in this research project
that developed into a full-term
pregnancy after being transferred to
surrogate mothers.
7. The research project that produced
CC was known as "Operation
CopyCat," and was part of a larger
project (called Missyplicity) to clone
a dog named Missy. Genetic
Savings & Clone, which provided
commercial gene banking and
cloning services to pet owners and
which closed in 2006, funded the
research.
8. CC was born at the College of
Veterinary Medicine at Texas A&M
University, under the direction of
Dr. Mark Westhusin, in
collaboration with Dr. Taeyoung
Shin. Her existence was announced
publicly on February 14, 2002, in
conjunction with the publication by
the scientific journal Nature of a
paper about the accomplishment.
9. CC now lives in the
household of Dr.
Duane Kraemer, one
of the scientists who
worked on with
project.
10. In September 2006, CC gave birth to
four kittens, two boys named Tim and Zip
and one girl named Tess who were fathered
naturally. One of the kittens, a girl, was
stillborn. This is the first time a cloned pet
has given birth. CC appears to be free of the
cloning-related health problems that have
arisen in some other animal clones. "CC has
always been a perfectly normal cat and her
kittens are just that way, too," says
Kraemer. "Weโve been monitoring their
health and all of them are fine, just like CC
has been for the past five years."[2]
