What do you do first if you get a boot message of Invalid System Disk? Solution this issue can be caused when seccurity softwere has disables access to drive C or windows setup was unable to copy the system files to hard disk or computer may be infected with a boot-sector virus. for resolve this issue uase an anti-virus program to detect and remove the virus and then reinstall windows,boot-sector virus infect computers by copying information either to boot sector on a floppy disk or partition table on a hard disk.during startup.During start up the virus is loaded into memory once in memory the virus tupically infects any non-infected disks that your computer is connected to. in some cases windows may not propery detect that you are using disk management sofwere and may overwrite the master boot record information. .