Food Chain and Food Web (Ecosystem) EVS, B. Pharmacy 1st Year, Sem-II
Extern jassdakorn suaypring
1.
2.
3. A : can speak , no stidor
c-spine - not tender/ movable
B : clear equal both lung , CCT negative
C : BP 114/71 mmHg , PR 96 bpm
no active bleeding , PCT negative
D : E4V5M6 , pupil 3 mm RTLBE
E : no external wound , no deformity
4. A : no allergy
M : no current medication
P : U/D : HT
L : 1 day ago
E : Next page -->
6. GA : aThai woman , alert,
HEENT: not pale, anicteric sclera
LN : no lymphadenopathy
Heart & Lung:WNL
Abdomen: soft, not tender
Extremities:Anvil & Rolling positive
Lt. hip - Marked tender , Limited ROM due to
pain , no wound / deformities
Lt. knee - Not tender , Full ROM
7.
8.
9. Both hip AP / Lt. lateral
: Osteolytic lesion at neck & head of Lt. femur
– ill defined border / no sclerotic rim /
no periosteal reaction / no soft tissue shadow
10. Closed fracture of Right neck of femur
Pathologic fracture
U/D: HT
11. Bone fracture which occurs without
adequate trauma and is caused by a
preexistent pathological bone lesion
(Distored archetecture /bone density)
13. Fractures more common in benign tumors
(vs malignant tumors)
most asymptomatic prior to fracture
antecedent nocturnal/rest symptoms rare
most common in children (humerus/femur)
: unicameral bone cyst, NOF, fibrous dysplasia,
eosinophilic granuloma
14. Fractures observed more often in
males than females
May be active or latent
Almost always solitary
First two decades
Humerus and femur most common
sites
“fallen fragment”sign
Fractures through benign tumors
15. Most common benign tumor
Femur, distal tibia, humerus
Multiple in 8% of patients
(associated with
neurofibromatosis)
Increased risk of pathologic
fracture in lesions >50%
bone diameter & >22mm
length
16. Solitary vs. multifocal
(solitary most common)
Femur and humerus
First and second decades
May be associated with
café au lait spots and
endocrinopathy
(Albright’s syndrome)
17. Relatively rare (often unsuspected)
May occur prior to or during treatment
May occur later in patients with radiation
osteonecrosis (Ewing’s, lymphoma)
Osteosarcoma, Ewing’s, malignant fibrous
histiocytoma, fibrosarcoma
22. Lab (rule out systemic conditions)
- ESR , CBC , serum Ca / PO4 / ALP
Skeletal Survey (rule out pending fracture in
axial skeleton, femurs, and humerus)
Bone scan
Bone marrow aspiration / biopsy
- Malignancy : the biopsy should be done
before fixation of the bone is undertaken.
23.
24.
25.
26.
27. Score < 7 (4%) - no need for prophylaxis
(conservative treatment)
Score 8 (15%) - border line
Score >9 (33%) - prophylactic fixation
28.
29. Like all fractures, reduction & immobilization
But a biopsy needs to be done first to define the
cause of the fracture.
Benign bony lesion, heal without surgery
Healing time is slower but can be expected to occur.
30. Nails versus plates versus arthroplasty
plates, screws and cement for torsional loads
interlocked nails stabilize entire bone
Cement augmentation
Radiation/chemotherapy/bisphosphonates
Aggressive rehabilitation
31. Ratio survival time : surgical recovery time
Ability to ambulate
Ability to use extremity
Capacity to return to full function
Pain not controlled by analgesics
Location of disease – high risk area