The document outlines a bystander opioid overdose reversal program implemented in Wilkes-Barre, PA. It found that 75% of overdose cases, the antagonist was administered by a friend. However, only 23% of bystanders called 911 due to fear of legal repercussions. The program aims to train friends and families to recognize overdoses and administer naloxone, an opioid antagonist that is safe and effective at reversing overdoses. It also educates about "Good Samaritan" laws providing immunity for those who call 911 to report an overdose. The program seeks to prevent opioid overdose deaths by empowering bystanders to intervene.
The Dallas Mavericks’ 2011 Run for the NBA ChampionshipStacy Cary
Stacy Stine Cary is an accomplished entrepreneur who has more than two decades of experience in the oil and gas exploration industry, in addition to real estate development and private equity investment. When she is not managing her various business endeavors, Stacy Cary supports Texas sports teams such as the Dallas Mavericks.
The Dallas Mavericks’ 2011 Run for the NBA ChampionshipStacy Cary
Stacy Stine Cary is an accomplished entrepreneur who has more than two decades of experience in the oil and gas exploration industry, in addition to real estate development and private equity investment. When she is not managing her various business endeavors, Stacy Cary supports Texas sports teams such as the Dallas Mavericks.
Opioid overdose has emerged as one of the leading causes of preventable death in the United States. Paramedics and emergency department staff know that naloxone is the best treatment for opioid overdose and have been using this antidote for over 40 years. In the past few years, programs distributing naloxone are being implemented by EMT-Basics, firefighters, law enforcement first responders and members of the community. Dr. Dailey served as the medical director for a New York State pilot project for the implementation of BLS naloxone, has trained law enforcement providers in several states and routinely prescribes naloxone to members of the community.
Antonio Boone of the Office of HIV Planning reviewed major points from the Mayor's Task Force to Combat the Opioid Epidemic in Philadelphia at the June 12, 2017 Positive Committee meeting.
Dr. Tom Frieden, Director of the Centers for Disease Control and Prevention, keynote presentation at the National Rx Drug Abuse & Heroin Summit on March 30, 2016.
Part of the "Fourth Annual Health Law Year in P/Review" held at Harvard Law School on January 29, 2016.
This symposium featured leading experts discussing major developments during 2015 and what to watch out for in 2016. The discussion covered hot topics in such areas as health insurance, health care systems, public health, innovation, and other issues facing clinicians and patients.
This year's Health Law Year in P/Review was sponsored by the Petrie-Flom Center for Health Law Policy, Biotechnology, and Bioethics at Harvard Law School, the New England Journal of Medicine, Health Affairs, the Hastings Center, Harvard Health Publications at Harvard Medical School, and the Center for Bioethics at Harvard Medical School, with support from the Oswald DeN. Cammann Fund at Harvard University.
Visit our website for more information: http://petrieflom.law.harvard.edu/events/details/fourth-annual-health-law-year-in-p-review.
Opioid Addiction: New Approach Gives Hope to Patients Awaiting TreatmentSov Addiction Rehab
Amid the growing opioid crisis in the United States, the capacity of available treatment programs is falling short of demand. As a result, people needing treatment for dependency on heroin or prescription painkillers have to wait for months, sometimes even years, to get appointments with certified doctors or to find slots in rehabilitation programs.
Getting treatment for an opioid use disorder will hopefully in turn reduce the number of overdoses and deaths related to opioid use.
Despite increased public awareness about the dangers of opioids, the epidemic continues in the US. What can we do to counter this deadly trend?
The numbers are striking.
Global Medical Cures™ | Responding to America's Prescription Drug Abuse CrisisGlobal Medical Cures™
Global Medical Cures™ | Responding to America's Prescription Drug Abuse Crisis
DISCLAIMER-
Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Opioid overdose has emerged as one of the leading causes of preventable death in the United States. Paramedics and emergency department staff know that naloxone is the best treatment for opioid overdose and have been using this antidote for over 40 years. In the past few years, programs distributing naloxone are being implemented by EMT-Basics, firefighters, law enforcement first responders and members of the community. Dr. Dailey served as the medical director for a New York State pilot project for the implementation of BLS naloxone, has trained law enforcement providers in several states and routinely prescribes naloxone to members of the community.
Antonio Boone of the Office of HIV Planning reviewed major points from the Mayor's Task Force to Combat the Opioid Epidemic in Philadelphia at the June 12, 2017 Positive Committee meeting.
Dr. Tom Frieden, Director of the Centers for Disease Control and Prevention, keynote presentation at the National Rx Drug Abuse & Heroin Summit on March 30, 2016.
Part of the "Fourth Annual Health Law Year in P/Review" held at Harvard Law School on January 29, 2016.
This symposium featured leading experts discussing major developments during 2015 and what to watch out for in 2016. The discussion covered hot topics in such areas as health insurance, health care systems, public health, innovation, and other issues facing clinicians and patients.
This year's Health Law Year in P/Review was sponsored by the Petrie-Flom Center for Health Law Policy, Biotechnology, and Bioethics at Harvard Law School, the New England Journal of Medicine, Health Affairs, the Hastings Center, Harvard Health Publications at Harvard Medical School, and the Center for Bioethics at Harvard Medical School, with support from the Oswald DeN. Cammann Fund at Harvard University.
Visit our website for more information: http://petrieflom.law.harvard.edu/events/details/fourth-annual-health-law-year-in-p-review.
Opioid Addiction: New Approach Gives Hope to Patients Awaiting TreatmentSov Addiction Rehab
Amid the growing opioid crisis in the United States, the capacity of available treatment programs is falling short of demand. As a result, people needing treatment for dependency on heroin or prescription painkillers have to wait for months, sometimes even years, to get appointments with certified doctors or to find slots in rehabilitation programs.
Getting treatment for an opioid use disorder will hopefully in turn reduce the number of overdoses and deaths related to opioid use.
Despite increased public awareness about the dangers of opioids, the epidemic continues in the US. What can we do to counter this deadly trend?
The numbers are striking.
Global Medical Cures™ | Responding to America's Prescription Drug Abuse CrisisGlobal Medical Cures™
Global Medical Cures™ | Responding to America's Prescription Drug Abuse Crisis
DISCLAIMER-
Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Thyroid Gland- Gross Anatomy by Dr. Rabia Inam Gandapore.pptx
Work sample
1. Bystander Opioid Overdose Reversal Medicine
Program for Friends and Families of at Risk
Residents in Wilkes-Barre, PA
Developed in collaboration by
Director: Ted Kross
Public Health Nurse: Delphine Torbik
Master’s of Public Health Intern: Melissa DeFina
Sept 2015 1
2. Fatal overdoses have increased dramatically in recent
years (Lisman, 2015).
Increase in deaths are primarily from non-medical use
of prescription pain relievers (opioids).
Heroin overdoses have also increased in many
communities (Pennsylvania State Coroners Association,
2014).
Overdose affects all sectors of society regardless of
income, ethnicity, gender, age or geography (Lisman,
2015).
2
3. During an 8-week period, the MPH candidate
will plan, design and implement a bystander
Opioid overdose reversal medicine program
for friends and families of at risk residents in
Wilkes-Barre, PA to decrease the occurrences
of death resulting from heroin and
prescription opioid overdose and lead the at
risk population toward the substance abuse
treatment they need.
3
5. Deaths caused by opioids are especially tragic
because they are PREVENTABLE (Bell & Doe-
Simkins, 2014).
A safe and effective way to administer an
antidote exists – naloxone hydrochloride;
also known as Narcan(Bell & Doe-Simkins,
2014).
5
6. In March of 2015 Wilkes-Barre City had
adopted the Narcan program to decrease the
number of Opioid overdoses (Kross, 2015).
Narcan is available to first responders to save
lives(Kross, 2015).
As of May 13th 2015 Wilkes-Barre has utilized
Narcan 10 times (Kross, 2015).
6
7. 90% of respondents (18 of 20) interviewed at REACH
and on the streets of WilkesBarre reported a drug
addiction problem (MHDSLW, 2013).
The average age of drug addiction onset for those
interviewed was 12 years of age (MHDSLW, 2013).
The cost of Narcan injectable has dramatically
increased now to approximately $425/dose (Kross,
2015).
7
8. The project will follow the program planning,
implementation and evaluation capstone project
path.
It will connect the current public health
intervention program of Opioid-associated
overdose and Naloxone training for the city and
health professionals developed in March of 2015
and enhanced in June (Kross, 2015).
This program will expanded the availability of
Naloxone and training to the public.
This capstone project is based off the Healthy
People topic of Substance Abuse.
8
9. Overdoses can occur with almost any drug
(HRC, 2015).
Most overdoses in the US are due to opioid
toxicity (poisoning) from drugs like
◦ Heroin
◦ Prescription pain relieves
Overdoses can occur with this drugs both on
there own or in combination with other
substances (HRC, 2015).
9
10. What are common opioids?
What opioid toxicity depend on.
Naloxone
Symptoms of Opioid-associated overdoses
10
12. How much was used (HRC, 2015).
The timing of use (HRC, 2015).
The user’s tolerance for the drug (HRC, 2015).
The user’s overall health (HRC, 2015).
Opioid-associated overdoses tend to occur after a
period of abstinence; such as (HRC, 2015):
Hospitalization.
Drug treatment.
Incarceration
Any period of time without use of the drug.
12
13. Naloxone only works with opioids (HRC, 2015).
If overdose is caused by an opioid combined with
other drugs, it may take longer for Naloxone
work (HRC, 2015).
If overdose is caused by other drugs like cocaine,
alcohol or acetaminophen; Naloxone will not
help, but it won’t hurt either (HRC, 2015).
IF IN DOUBT, USE NALOXONE
13
14. Naloxone is a highly effective opioid
antagonist (CDC, 2012).
It blocks effects of opioids on the brain’s
respiratory control center (CDC, 2012).
Quickly reverses effects of opioid (CDC,
2012).
It restores respiration rates depressed by the
overdose (CDC, 2012).
NALOXONE IS THE ANTIDOTE FOR AN
OPIOID-ASSOCIATED OVERDOSE
14
15. Breathing is suppressed (slow or no breathing)
Unconsciousness
Cyanosis (lips and nail beds are ashen, blue or
purple)
Pale or clammy skin
Gurgling or snoring (a.k.a. “dealth rattle”)
(HRC, 2015).
15
16. A person who is really
high
A person who is
overdoing
WILL RESPOND to
stimulation (calling out
there name or sternum
rub)
Has small, pinpoint
pupils
Slowed or slurred
speech
Looks sleepy
WILL NOT RESPOND to
stimulation.
And often
Has bluish lips or nail
beds
Infrequent or no
breathing (less then 8
breaths per minute)
Snoring or gurgling
Slow, erratic or no
pulse.
(HRC, 2015)
16
17. Follow Wilkes-Barre standard resuscitation
protocol.
Opioid overdose is an exception to the chest
compression protocol ONLY- IMMEDIATE
ventilation is VITAL.
17
18. 1. Place the victim on their back
2. Tilt chin up to open airway
3. Look to see there is nothing in the mouth
blocking airway.
4. Place bag valve mask over face and pinch
nose
5. Give two even, regular-sized breaths to
make chest rise. (if no chest rise re-tilt head
and make sure nose is pinched).
6. Give one breath every five seconds.
(HRC, 2014)
18
19. One responder Two responders
Give rescue breathing
Call 911
Give rescue breathing
administers Narcan
Divide the duties
1st person calls 911.
2nd gives rescue
breathing, conts
1st person administers
Narcan.
(HRC, 2014)
19
21. 1. Do rescue breathing if the person is not breathing.
2. Affix the nasal applicator to the needleless syringe
and then assemble the naloxone cartridge.
3. Tilt the head back and spray half of the naloxone
up one side of the nose (1cc) and half up the other
side of the nose (1cc).
4. If there is no breathing or breathing continues to be
shallow, continue to perform rescue breathing for
them while waiting for the naloxone to take effect.
5. If there is no change in 3-5 minutes, administer
another dose of naloxone and continue to breathe
for them.
(HRC, 2014)
21
22. The bystander Opioid overdose reversal medicine
program for friends and families of at risk
residents in Wilkes-Barre, PA the results show
that out of all 425 reported overdose cases, 75%
of the cases the opioid antagonist was
administered by a friend (Kross, 2015).
The bystander Opioid overdose reversal medicine
program for friends and families of at risk
residents in Wilkes-Barre, PA has also shown that
only 23% bystander called 911. This low rate is
attributed to concern on the part of many
bystanders that if they called the authorities, they
risked arrest for drug possession (Kross, 2015).
22
23. Are intended to maximize the willingness to
call 911 - IN PA THE LAW IS:
35 PA. Cons. Stat. § 780-
113.7 Drug overdose response
immunity Drug Overdose Response Immunity
Signed into law on September 30.
This new law encourages a person to act the
‘Good Samaritan,’ and call the authorities
immediately, when they encounters a
possible life-threatening drug overdose.
23
24. “A person may not be charged and shall be
immune from prosecution for any offense listed
in subsection b) and for a violation of probation
or parole if the person can establish the
following”:
a) law enforcement officers only became
aware of the person's commission of an offense
listed in subsection
b) because the person transported a person
experiencing a drug overdose event to a law
enforcement agency, a campus security office or
a health care facility; or
24
25. ii. all of the following apply:
1. the person reported, in good faith, a drug overdose event to a law
enforcement officer, the 911 system, a campus security officer or
emergency services personnel and the report was made on the
reasonable belief that another person was in need of immediate medical
attention and was necessary to prevent death or serious bodily injury
due to a drug overdose;
2. the person provided his own name and location and cooperated
with the law enforcement officer, 911 system, campus security officer or
emergency services personnel; and
3. the person remained with the person needing immediate medical
attention until a law enforcement officer, a campus security officer or
emergency services personnel arrived.
b) The prohibition on charging or prosecuting a person as described in
subsection a) bars charging or prosecuting a person for probation and
parole violations and for violations of section 13(a)(5), (16), (19), (31),
(32), (33) and (37).
c) Persons experiencing drug overdose events may not be charged
and shall be immune from prosecution as provided in subsection b) if a
person who transported or reported and remained with them may not be
charged and is entitled to immunity under this section.
25
26. Bystander Opioid overdose reversal medicine program for
friends and families of at risk residents in Wilkes-Barre, PA
will help to prevent death due to Opioid related overdoses.
It will use training and educational tools to help family
members save the others of loved ones. In this program I
have been able to take on many responsibilities and
perform many actives that have been vital to the Bystander
Opioid overdose reversal medicine program for friends
and families of at risk residents in Wilkes-Barre, PA. The
use of Naloxone is an eminently safe and nonabusable
substance that has only one pharmacological function and
that is to reverse the effects of opioids on the brain and
respiratory system in order to prevent the ultimate adverse
event of death (CDC, 2012).
26
27. Bell, A., & Doe-Simkins, M. (2014). Opioid overdose prevention and
related trauma: incorporating overdose prevention, response,
and experience into substance use disorder treatment. Retrieved
from http://prescribetoprevent.org/wp2015/wp-
content/uploads/Incorporating-OD-into-SUD-Tx-12.141.pdf
CDC. (2012). Community-Based Opioid Overdose Prevention
Programs Providing Naloxone — United States, 2010. Retrieved
from
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6106a1.htm
HRC. (2014). Administer Naloxone. Retrieved from
http://harmreduction.org/issues/overdose-
prevention/overview/overdose-basics/responding-to-opioid-
overdose/administer-naloxone/
27
28. HRC. (2015). Recognizing Opioid Overdose. Retrieved from
http://harmreduction.org/issues/overdose-
prevention/overview/overdose-basics/recognizing-opioid-
overdose/
Kross, T. (2015). Wilkes-Barre health department. (M. DeFina,
Interviewer)
Lisman, W. (2015). Coroner William Lisman calls pinpointing drugs
that cause overdose deaths difficult. Retrieved from
http://www.timesleader.com/news/local-news/152834330/
28
29. MHDSLW. (2013). Luzerne-wyoming counties mh/mr program,
Annual mental health plan update, Fiscal year 2013-2017 .
Retrieved from
http://www.mhdslw.org/uploads/documents/Electronic%20Versi
on%20%20%20MH%20Plan%2012-13.pdf
Pennsylvania State Coroners Association. (2014). Heroin Overdose
Death Report2009 – 2013. Retrieved from
http://www.co.westmoreland.pa.us/Archive/ViewFile/Item/495
29
Editor's Notes
Accidental drug overdoses are the leading killer of Luzerne County residents in 2014 after deaths from natural causes (Lisman, 2015).
Bystander Opioid overdose reversal medicine program for friends and families of at risk residents in Wilkes-Barre, PA is a Opioid related drug overdoses prevention program that provides educational sessions, availability and use of Naloxone.
This graph shows how Luzerne County compared to the state from 2009 to 2013. MULTI DRUG TOXICITY, refers to the combination of Heroin and one or more other opiates, illicit drugs, or prescription drugs found through toxicology. Overdose deaths in Luzerne County were 64 in 2014, according to data released by the county coroner’s office (Lisman,2014). In comparison, 39 people who died in motor vehicle accidents in 2014.
Naloxone restores respirations rates that have been depressed by the overdose (Bell & Doe-Simkins, 2014). It has no psychoactive properties, is not a controlled drug and has no abuse potential (Bell & Doe-Simkins, 2014).
The use of Narcan can decrease the deaths (ultimate goal) and indirectly decrease the growing expenses of EMS, Emergency departments and hospital systems for resuscitative care (Kross, 2015).
The purpose of this proposal is to introduce a program that focuses on the prevention of death due to Opioid related overdoses in the city of Wilkes-Barre, PA.
Poly-drug use (combining an opioid with other substances) can increase the risk of a fatal overdose (HRC, 2015).
Often when people can no longer get prescription drug they will move to street drugs (HRC, 2015).
Even a relatively small amount of an opioid can lead to an overdose emergency when tolerance is low.
The depression of respiration usually occurs gradually (over minutes or even hours), there for there is usually time to intervene. If no one intervenes, the overdose victim will die of oxygen deprivation (HRC, 2015).
Overdose from cocaine can include: dilated pupils, agitation, high blood pressure, high temperature, seizures, or chest pains (HRC, 2015).
If the second dose of naloxone does not revive them, something else is wrong—either it has been too long and the heart has already stopped, there are no opioids in their system, or the opioids are unusually strong and require more naloxone (can happen with Fentanyl, for example) (HRC, 2014).
There are laws in place so that this concern is not possible yet public belief has lead to this fear. This aspects needs to be better addressed; possibly with role-playing actives that show the possible outcomes when just rescue breathing and administering naloxone is used without calling emergency personnel for further care.
Before passage of Act No. 136, a person who did the right thing, and called the authorities, about a overdose on drugs was often rewarded with criminal charges, this served as a powerful disincentive to calling 911.