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Bystander Opioid Overdose Reversal Medicine
Program for Friends and Families of at Risk
Residents in Wilkes-Barre, PA
Developed in collaboration by
Director: Ted Kross
Public Health Nurse: Delphine Torbik
Master’s of Public Health Intern: Melissa DeFina
Sept 2015 1
 Fatal overdoses have increased dramatically in recent
years (Lisman, 2015).
 Increase in deaths are primarily from non-medical use
of prescription pain relievers (opioids).
 Heroin overdoses have also increased in many
communities (Pennsylvania State Coroners Association,
2014).
 Overdose affects all sectors of society regardless of
income, ethnicity, gender, age or geography (Lisman,
2015).
2
 During an 8-week period, the MPH candidate
will plan, design and implement a bystander
Opioid overdose reversal medicine program
for friends and families of at risk residents in
Wilkes-Barre, PA to decrease the occurrences
of death resulting from heroin and
prescription opioid overdose and lead the at
risk population toward the substance abuse
treatment they need.
3
(Pennsylvania State Coroners Association, 2014)
4
 Deaths caused by opioids are especially tragic
because they are PREVENTABLE (Bell & Doe-
Simkins, 2014).
 A safe and effective way to administer an
antidote exists – naloxone hydrochloride;
also known as Narcan(Bell & Doe-Simkins,
2014).
5
 In March of 2015 Wilkes-Barre City had
adopted the Narcan program to decrease the
number of Opioid overdoses (Kross, 2015).
 Narcan is available to first responders to save
lives(Kross, 2015).
 As of May 13th 2015 Wilkes-Barre has utilized
Narcan 10 times (Kross, 2015).
6
 90% of respondents (18 of 20) interviewed at REACH
and on the streets of WilkesBarre reported a drug
addiction problem (MHDSLW, 2013).
 The average age of drug addiction onset for those
interviewed was 12 years of age (MHDSLW, 2013).
 The cost of Narcan injectable has dramatically
increased now to approximately $425/dose (Kross,
2015).
7
 The project will follow the program planning,
implementation and evaluation capstone project
path.
 It will connect the current public health
intervention program of Opioid-associated
overdose and Naloxone training for the city and
health professionals developed in March of 2015
and enhanced in June (Kross, 2015).
 This program will expanded the availability of
Naloxone and training to the public.
 This capstone project is based off the Healthy
People topic of Substance Abuse.
8
 Overdoses can occur with almost any drug
(HRC, 2015).
 Most overdoses in the US are due to opioid
toxicity (poisoning) from drugs like
◦ Heroin
◦ Prescription pain relieves
 Overdoses can occur with this drugs both on
there own or in combination with other
substances (HRC, 2015).
9
 What are common opioids?
 What opioid toxicity depend on.
 Naloxone
 Symptoms of Opioid-associated overdoses
10
Street Drugs Prescription
 Heroin (slang: junk,
dope, smack, shot,
shit, h, & manteca)
 Opium (slang: O.P.,
hop, midnight oil, tar,
dope, Big O)
(HRC, 2015).
 Codeine (Tylenol 3®)
 Fentanyl (Duragesic®)
 Hydrocodone (Vicodin®, Norco®,
Lortab®, Lorcet®)
 Hydromorphone (Dilaudid®)
 Meperidine (Demerol®)
 Morphine (Astramorph®, Avinza®,
Kadian®, MS Contin®)
 Oxycodone (OxyContin®,
Percocet®, Percodan®)
 Oxymorphone (Opana®)
 Levorphanol (Levo-Dromoran®)
 Methadone Dolophine®)
11
 How much was used (HRC, 2015).
 The timing of use (HRC, 2015).
 The user’s tolerance for the drug (HRC, 2015).
 The user’s overall health (HRC, 2015).
Opioid-associated overdoses tend to occur after a
period of abstinence; such as (HRC, 2015):
 Hospitalization.
 Drug treatment.
 Incarceration
 Any period of time without use of the drug.
12
 Naloxone only works with opioids (HRC, 2015).
 If overdose is caused by an opioid combined with
other drugs, it may take longer for Naloxone
work (HRC, 2015).
 If overdose is caused by other drugs like cocaine,
alcohol or acetaminophen; Naloxone will not
help, but it won’t hurt either (HRC, 2015).
IF IN DOUBT, USE NALOXONE
13
 Naloxone is a highly effective opioid
antagonist (CDC, 2012).
 It blocks effects of opioids on the brain’s
respiratory control center (CDC, 2012).
 Quickly reverses effects of opioid (CDC,
2012).
 It restores respiration rates depressed by the
overdose (CDC, 2012).
NALOXONE IS THE ANTIDOTE FOR AN
OPIOID-ASSOCIATED OVERDOSE
14
 Breathing is suppressed (slow or no breathing)
 Unconsciousness
 Cyanosis (lips and nail beds are ashen, blue or
purple)
 Pale or clammy skin
 Gurgling or snoring (a.k.a. “dealth rattle”)
(HRC, 2015).
15
A person who is really
high
A person who is
overdoing
 WILL RESPOND to
stimulation (calling out
there name or sternum
rub)
 Has small, pinpoint
pupils
 Slowed or slurred
speech
 Looks sleepy
 WILL NOT RESPOND to
stimulation.
And often
 Has bluish lips or nail
beds
 Infrequent or no
breathing (less then 8
breaths per minute)
 Snoring or gurgling
 Slow, erratic or no
pulse.
(HRC, 2015)
16
 Follow Wilkes-Barre standard resuscitation
protocol.
 Opioid overdose is an exception to the chest
compression protocol ONLY- IMMEDIATE
ventilation is VITAL.
17
1. Place the victim on their back
2. Tilt chin up to open airway
3. Look to see there is nothing in the mouth
blocking airway.
4. Place bag valve mask over face and pinch
nose
5. Give two even, regular-sized breaths to
make chest rise. (if no chest rise re-tilt head
and make sure nose is pinched).
6. Give one breath every five seconds.
(HRC, 2014)
18
One responder Two responders
 Give rescue breathing
 Call 911
 Give rescue breathing
 administers Narcan
 Divide the duties
 1st person calls 911.
 2nd gives rescue
breathing, conts
 1st person administers
Narcan.
(HRC, 2014)
19
(HRC, 2014) 20
1. Do rescue breathing if the person is not breathing.
2. Affix the nasal applicator to the needleless syringe
and then assemble the naloxone cartridge.
3. Tilt the head back and spray half of the naloxone
up one side of the nose (1cc) and half up the other
side of the nose (1cc).
4. If there is no breathing or breathing continues to be
shallow, continue to perform rescue breathing for
them while waiting for the naloxone to take effect.
5. If there is no change in 3-5 minutes, administer
another dose of naloxone and continue to breathe
for them.
(HRC, 2014)
21
 The bystander Opioid overdose reversal medicine
program for friends and families of at risk
residents in Wilkes-Barre, PA the results show
that out of all 425 reported overdose cases, 75%
of the cases the opioid antagonist was
administered by a friend (Kross, 2015).
 The bystander Opioid overdose reversal medicine
program for friends and families of at risk
residents in Wilkes-Barre, PA has also shown that
only 23% bystander called 911. This low rate is
attributed to concern on the part of many
bystanders that if they called the authorities, they
risked arrest for drug possession (Kross, 2015).
22
 Are intended to maximize the willingness to
call 911 - IN PA THE LAW IS:
 35 PA. Cons. Stat. § 780-
113.7 Drug overdose response
immunity Drug Overdose Response Immunity
 Signed into law on September 30.
 This new law encourages a person to act the
‘Good Samaritan,’ and call the authorities
immediately, when they encounters a
possible life-threatening drug overdose.
23
“A person may not be charged and shall be
immune from prosecution for any offense listed
in subsection b) and for a violation of probation
or parole if the person can establish the
following”:
a) law enforcement officers only became
aware of the person's commission of an offense
listed in subsection
b) because the person transported a person
experiencing a drug overdose event to a law
enforcement agency, a campus security office or
a health care facility; or
24
ii. all of the following apply:
 1. the person reported, in good faith, a drug overdose event to a law
enforcement officer, the 911 system, a campus security officer or
emergency services personnel and the report was made on the
reasonable belief that another person was in need of immediate medical
attention and was necessary to prevent death or serious bodily injury
due to a drug overdose;
 2. the person provided his own name and location and cooperated
with the law enforcement officer, 911 system, campus security officer or
emergency services personnel; and
 3. the person remained with the person needing immediate medical
attention until a law enforcement officer, a campus security officer or
emergency services personnel arrived.
 b) The prohibition on charging or prosecuting a person as described in
subsection a) bars charging or prosecuting a person for probation and
parole violations and for violations of section 13(a)(5), (16), (19), (31),
(32), (33) and (37).
 c) Persons experiencing drug overdose events may not be charged
and shall be immune from prosecution as provided in subsection b) if a
person who transported or reported and remained with them may not be
charged and is entitled to immunity under this section.
25
 Bystander Opioid overdose reversal medicine program for
friends and families of at risk residents in Wilkes-Barre, PA
will help to prevent death due to Opioid related overdoses.
It will use training and educational tools to help family
members save the others of loved ones. In this program I
have been able to take on many responsibilities and
perform many actives that have been vital to the Bystander
Opioid overdose reversal medicine program for friends
and families of at risk residents in Wilkes-Barre, PA. The
use of Naloxone is an eminently safe and nonabusable
substance that has only one pharmacological function and
that is to reverse the effects of opioids on the brain and
respiratory system in order to prevent the ultimate adverse
event of death (CDC, 2012).
26
Bell, A., & Doe-Simkins, M. (2014). Opioid overdose prevention and
related trauma: incorporating overdose prevention, response,
and experience into substance use disorder treatment. Retrieved
from http://prescribetoprevent.org/wp2015/wp-
content/uploads/Incorporating-OD-into-SUD-Tx-12.141.pdf
CDC. (2012). Community-Based Opioid Overdose Prevention
Programs Providing Naloxone — United States, 2010. Retrieved
from
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6106a1.htm
HRC. (2014). Administer Naloxone. Retrieved from
http://harmreduction.org/issues/overdose-
prevention/overview/overdose-basics/responding-to-opioid-
overdose/administer-naloxone/
27
HRC. (2015). Recognizing Opioid Overdose. Retrieved from
http://harmreduction.org/issues/overdose-
prevention/overview/overdose-basics/recognizing-opioid-
overdose/
Kross, T. (2015). Wilkes-Barre health department. (M. DeFina,
Interviewer)
Lisman, W. (2015). Coroner William Lisman calls pinpointing drugs
that cause overdose deaths difficult. Retrieved from
http://www.timesleader.com/news/local-news/152834330/
28
MHDSLW. (2013). Luzerne-wyoming counties mh/mr program,
Annual mental health plan update, Fiscal year 2013-2017 .
Retrieved from
http://www.mhdslw.org/uploads/documents/Electronic%20Versi
on%20%20%20MH%20Plan%2012-13.pdf
Pennsylvania State Coroners Association. (2014). Heroin Overdose
Death Report2009 – 2013. Retrieved from
http://www.co.westmoreland.pa.us/Archive/ViewFile/Item/495
29

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Work sample

  • 1. Bystander Opioid Overdose Reversal Medicine Program for Friends and Families of at Risk Residents in Wilkes-Barre, PA Developed in collaboration by Director: Ted Kross Public Health Nurse: Delphine Torbik Master’s of Public Health Intern: Melissa DeFina Sept 2015 1
  • 2.  Fatal overdoses have increased dramatically in recent years (Lisman, 2015).  Increase in deaths are primarily from non-medical use of prescription pain relievers (opioids).  Heroin overdoses have also increased in many communities (Pennsylvania State Coroners Association, 2014).  Overdose affects all sectors of society regardless of income, ethnicity, gender, age or geography (Lisman, 2015). 2
  • 3.  During an 8-week period, the MPH candidate will plan, design and implement a bystander Opioid overdose reversal medicine program for friends and families of at risk residents in Wilkes-Barre, PA to decrease the occurrences of death resulting from heroin and prescription opioid overdose and lead the at risk population toward the substance abuse treatment they need. 3
  • 4. (Pennsylvania State Coroners Association, 2014) 4
  • 5.  Deaths caused by opioids are especially tragic because they are PREVENTABLE (Bell & Doe- Simkins, 2014).  A safe and effective way to administer an antidote exists – naloxone hydrochloride; also known as Narcan(Bell & Doe-Simkins, 2014). 5
  • 6.  In March of 2015 Wilkes-Barre City had adopted the Narcan program to decrease the number of Opioid overdoses (Kross, 2015).  Narcan is available to first responders to save lives(Kross, 2015).  As of May 13th 2015 Wilkes-Barre has utilized Narcan 10 times (Kross, 2015). 6
  • 7.  90% of respondents (18 of 20) interviewed at REACH and on the streets of WilkesBarre reported a drug addiction problem (MHDSLW, 2013).  The average age of drug addiction onset for those interviewed was 12 years of age (MHDSLW, 2013).  The cost of Narcan injectable has dramatically increased now to approximately $425/dose (Kross, 2015). 7
  • 8.  The project will follow the program planning, implementation and evaluation capstone project path.  It will connect the current public health intervention program of Opioid-associated overdose and Naloxone training for the city and health professionals developed in March of 2015 and enhanced in June (Kross, 2015).  This program will expanded the availability of Naloxone and training to the public.  This capstone project is based off the Healthy People topic of Substance Abuse. 8
  • 9.  Overdoses can occur with almost any drug (HRC, 2015).  Most overdoses in the US are due to opioid toxicity (poisoning) from drugs like ◦ Heroin ◦ Prescription pain relieves  Overdoses can occur with this drugs both on there own or in combination with other substances (HRC, 2015). 9
  • 10.  What are common opioids?  What opioid toxicity depend on.  Naloxone  Symptoms of Opioid-associated overdoses 10
  • 11. Street Drugs Prescription  Heroin (slang: junk, dope, smack, shot, shit, h, & manteca)  Opium (slang: O.P., hop, midnight oil, tar, dope, Big O) (HRC, 2015).  Codeine (Tylenol 3®)  Fentanyl (Duragesic®)  Hydrocodone (Vicodin®, Norco®, Lortab®, Lorcet®)  Hydromorphone (Dilaudid®)  Meperidine (Demerol®)  Morphine (Astramorph®, Avinza®, Kadian®, MS Contin®)  Oxycodone (OxyContin®, Percocet®, Percodan®)  Oxymorphone (Opana®)  Levorphanol (Levo-Dromoran®)  Methadone Dolophine®) 11
  • 12.  How much was used (HRC, 2015).  The timing of use (HRC, 2015).  The user’s tolerance for the drug (HRC, 2015).  The user’s overall health (HRC, 2015). Opioid-associated overdoses tend to occur after a period of abstinence; such as (HRC, 2015):  Hospitalization.  Drug treatment.  Incarceration  Any period of time without use of the drug. 12
  • 13.  Naloxone only works with opioids (HRC, 2015).  If overdose is caused by an opioid combined with other drugs, it may take longer for Naloxone work (HRC, 2015).  If overdose is caused by other drugs like cocaine, alcohol or acetaminophen; Naloxone will not help, but it won’t hurt either (HRC, 2015). IF IN DOUBT, USE NALOXONE 13
  • 14.  Naloxone is a highly effective opioid antagonist (CDC, 2012).  It blocks effects of opioids on the brain’s respiratory control center (CDC, 2012).  Quickly reverses effects of opioid (CDC, 2012).  It restores respiration rates depressed by the overdose (CDC, 2012). NALOXONE IS THE ANTIDOTE FOR AN OPIOID-ASSOCIATED OVERDOSE 14
  • 15.  Breathing is suppressed (slow or no breathing)  Unconsciousness  Cyanosis (lips and nail beds are ashen, blue or purple)  Pale or clammy skin  Gurgling or snoring (a.k.a. “dealth rattle”) (HRC, 2015). 15
  • 16. A person who is really high A person who is overdoing  WILL RESPOND to stimulation (calling out there name or sternum rub)  Has small, pinpoint pupils  Slowed or slurred speech  Looks sleepy  WILL NOT RESPOND to stimulation. And often  Has bluish lips or nail beds  Infrequent or no breathing (less then 8 breaths per minute)  Snoring or gurgling  Slow, erratic or no pulse. (HRC, 2015) 16
  • 17.  Follow Wilkes-Barre standard resuscitation protocol.  Opioid overdose is an exception to the chest compression protocol ONLY- IMMEDIATE ventilation is VITAL. 17
  • 18. 1. Place the victim on their back 2. Tilt chin up to open airway 3. Look to see there is nothing in the mouth blocking airway. 4. Place bag valve mask over face and pinch nose 5. Give two even, regular-sized breaths to make chest rise. (if no chest rise re-tilt head and make sure nose is pinched). 6. Give one breath every five seconds. (HRC, 2014) 18
  • 19. One responder Two responders  Give rescue breathing  Call 911  Give rescue breathing  administers Narcan  Divide the duties  1st person calls 911.  2nd gives rescue breathing, conts  1st person administers Narcan. (HRC, 2014) 19
  • 21. 1. Do rescue breathing if the person is not breathing. 2. Affix the nasal applicator to the needleless syringe and then assemble the naloxone cartridge. 3. Tilt the head back and spray half of the naloxone up one side of the nose (1cc) and half up the other side of the nose (1cc). 4. If there is no breathing or breathing continues to be shallow, continue to perform rescue breathing for them while waiting for the naloxone to take effect. 5. If there is no change in 3-5 minutes, administer another dose of naloxone and continue to breathe for them. (HRC, 2014) 21
  • 22.  The bystander Opioid overdose reversal medicine program for friends and families of at risk residents in Wilkes-Barre, PA the results show that out of all 425 reported overdose cases, 75% of the cases the opioid antagonist was administered by a friend (Kross, 2015).  The bystander Opioid overdose reversal medicine program for friends and families of at risk residents in Wilkes-Barre, PA has also shown that only 23% bystander called 911. This low rate is attributed to concern on the part of many bystanders that if they called the authorities, they risked arrest for drug possession (Kross, 2015). 22
  • 23.  Are intended to maximize the willingness to call 911 - IN PA THE LAW IS:  35 PA. Cons. Stat. § 780- 113.7 Drug overdose response immunity Drug Overdose Response Immunity  Signed into law on September 30.  This new law encourages a person to act the ‘Good Samaritan,’ and call the authorities immediately, when they encounters a possible life-threatening drug overdose. 23
  • 24. “A person may not be charged and shall be immune from prosecution for any offense listed in subsection b) and for a violation of probation or parole if the person can establish the following”: a) law enforcement officers only became aware of the person's commission of an offense listed in subsection b) because the person transported a person experiencing a drug overdose event to a law enforcement agency, a campus security office or a health care facility; or 24
  • 25. ii. all of the following apply:  1. the person reported, in good faith, a drug overdose event to a law enforcement officer, the 911 system, a campus security officer or emergency services personnel and the report was made on the reasonable belief that another person was in need of immediate medical attention and was necessary to prevent death or serious bodily injury due to a drug overdose;  2. the person provided his own name and location and cooperated with the law enforcement officer, 911 system, campus security officer or emergency services personnel; and  3. the person remained with the person needing immediate medical attention until a law enforcement officer, a campus security officer or emergency services personnel arrived.  b) The prohibition on charging or prosecuting a person as described in subsection a) bars charging or prosecuting a person for probation and parole violations and for violations of section 13(a)(5), (16), (19), (31), (32), (33) and (37).  c) Persons experiencing drug overdose events may not be charged and shall be immune from prosecution as provided in subsection b) if a person who transported or reported and remained with them may not be charged and is entitled to immunity under this section. 25
  • 26.  Bystander Opioid overdose reversal medicine program for friends and families of at risk residents in Wilkes-Barre, PA will help to prevent death due to Opioid related overdoses. It will use training and educational tools to help family members save the others of loved ones. In this program I have been able to take on many responsibilities and perform many actives that have been vital to the Bystander Opioid overdose reversal medicine program for friends and families of at risk residents in Wilkes-Barre, PA. The use of Naloxone is an eminently safe and nonabusable substance that has only one pharmacological function and that is to reverse the effects of opioids on the brain and respiratory system in order to prevent the ultimate adverse event of death (CDC, 2012). 26
  • 27. Bell, A., & Doe-Simkins, M. (2014). Opioid overdose prevention and related trauma: incorporating overdose prevention, response, and experience into substance use disorder treatment. Retrieved from http://prescribetoprevent.org/wp2015/wp- content/uploads/Incorporating-OD-into-SUD-Tx-12.141.pdf CDC. (2012). Community-Based Opioid Overdose Prevention Programs Providing Naloxone — United States, 2010. Retrieved from http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6106a1.htm HRC. (2014). Administer Naloxone. Retrieved from http://harmreduction.org/issues/overdose- prevention/overview/overdose-basics/responding-to-opioid- overdose/administer-naloxone/ 27
  • 28. HRC. (2015). Recognizing Opioid Overdose. Retrieved from http://harmreduction.org/issues/overdose- prevention/overview/overdose-basics/recognizing-opioid- overdose/ Kross, T. (2015). Wilkes-Barre health department. (M. DeFina, Interviewer) Lisman, W. (2015). Coroner William Lisman calls pinpointing drugs that cause overdose deaths difficult. Retrieved from http://www.timesleader.com/news/local-news/152834330/ 28
  • 29. MHDSLW. (2013). Luzerne-wyoming counties mh/mr program, Annual mental health plan update, Fiscal year 2013-2017 . Retrieved from http://www.mhdslw.org/uploads/documents/Electronic%20Versi on%20%20%20MH%20Plan%2012-13.pdf Pennsylvania State Coroners Association. (2014). Heroin Overdose Death Report2009 – 2013. Retrieved from http://www.co.westmoreland.pa.us/Archive/ViewFile/Item/495 29

Editor's Notes

  1. Accidental drug overdoses are the leading killer of Luzerne County residents in 2014 after deaths from natural causes (Lisman, 2015).
  2. Bystander Opioid overdose reversal medicine program for friends and families of at risk residents in Wilkes-Barre, PA is a Opioid related drug overdoses prevention program that provides educational sessions, availability and use of Naloxone.
  3. This graph shows how Luzerne County compared to the state from 2009 to 2013. MULTI DRUG TOXICITY, refers to the combination of Heroin and one or more other opiates, illicit drugs, or prescription drugs found through toxicology. Overdose deaths in Luzerne County were 64 in 2014, according to data released by the county coroner’s office (Lisman,2014). In comparison, 39 people who died in motor vehicle accidents in 2014.
  4. Naloxone restores respirations rates that have been depressed by the overdose (Bell & Doe-Simkins, 2014). It has no psychoactive properties, is not a controlled drug and has no abuse potential (Bell & Doe-Simkins, 2014).
  5. The use of Narcan can decrease the deaths (ultimate goal) and indirectly decrease the growing expenses of  EMS, Emergency departments and hospital systems for resuscitative care (Kross, 2015).
  6. The purpose of this proposal is to introduce a program that focuses on the prevention of death due to Opioid related overdoses in the city of Wilkes-Barre, PA.
  7. Poly-drug use (combining an opioid with other substances) can increase the risk of a fatal overdose (HRC, 2015).
  8. Often when people can no longer get prescription drug they will move to street drugs (HRC, 2015).
  9. Even a relatively small amount of an opioid can lead to an overdose emergency when tolerance is low.
  10. The depression of respiration usually occurs gradually (over minutes or even hours), there for there is usually time to intervene. If no one intervenes, the overdose victim will die of oxygen deprivation (HRC, 2015).
  11. Overdose from cocaine can include: dilated pupils, agitation, high blood pressure, high temperature, seizures, or chest pains (HRC, 2015).
  12. If the second dose of naloxone does not revive them, something else is wrong—either it has been too long and the heart has already stopped, there are no opioids in their system, or the opioids are unusually strong and require more naloxone (can happen with Fentanyl, for example) (HRC, 2014).
  13. There are laws in place so that this concern is not possible yet public belief has lead to this fear. This aspects needs to be better addressed; possibly with role-playing actives that show the possible outcomes when just rescue breathing and administering naloxone is used without calling emergency personnel for further care.
  14. Before passage of Act No. 136, a person who did the right thing, and called the authorities, about a overdose on drugs was often rewarded with criminal charges, this served as a powerful disincentive to calling 911.