A website wireframe is a visual guide that represents the framework of a website, including the structure and placement of key elements like headers, footers, navigation, and content. Wireframes typically contain placeholders for branding, images, and content, as well as a site map showing page locations. They focus on the kinds of information displayed, available functions, and how different scenarios affect the layout. Wireframes are used by designers to initiate the design process, clients to understand business priorities, project teams to ensure requirements are met, and developers to identify technical requirements.