Wireframing is a crucial part of the screen design process, enabling rapid ideation and providing developers with a clear layout of the necessary coding elements, including headers, footers, and sidebars. It serves multiple purposes, aiding in the connection between a site’s information architecture and visual design, while focusing on space allocation and content prioritization. To create effective wireframes, it's recommended to avoid colors and images, use a single generic font, and consider content organization, hierarchy, functionality, and user interaction.