Wind River's VxWorks real-time operating system plays a central role in NASA's Mars rover Curiosity mission by controlling the rover's functions from launch to completion of its mission. VxWorks manages critical operations like navigation, descent, landing, collecting science data, and transmitting data back to Earth. It helped enable the complex and risky landing sequence within a small target zone on Mars. VxWorks has supported over 20 NASA missions due to its reliable and resilient nature which is essential for missions with no room for failure.