Appium is an open source tool that can automate testing of native, hybrid, and mobile web applications on iOS and Android devices. It allows testing on physical devices as well as emulators without needing to modify the app code. Appium uses the WebDriver API and JSON wire protocol to communicate between a client library and the Appium server, which interacts directly with the device OS to automate apps using UIAutomator2 on Android and XCUITest on iOS.