2. MENINGES
THREE LAYERS OF MEMBRANE KNOWS AS
MENINGES PROTECT THE BRAIN AND SPINAL
CORD.
INNER LAYER IS THE PIA MATER.
MIDDLE LAYER IS THE ARACHONOID MATER
THIS LAYER WEB LIKE STRUCTURE FILLD
OUTER LAYER IS THE DURA MATER
MENINGES IS PROVIDE PROTECTION AND
COVER BRAIN & SPINAL CORD
3. MENINGITIS
MENINGITIS IS AN INFLAMMATION OF THE
BRAIN AND SPINAL CORD MEMBRANES
TYPICALLY CAUSED BY AN INFECTION.
MENINGITIS IS INFLAMATION OF THE
PROTECTIVE MEMBRANES COVERING THE
BRAIN AND SPINAL CORD, KNOWN AS THE
MENINGES.
SWELLING AND INFLAMATION IN BRAIN,
PATIENT HAVE HEADACHE.
BACTERAIL MENINGITIS IS MORE COMMON
IN INFANT, UNDER 1 YEAR OF AGE & PEOPLE
AGES 16-21.
4. TYPES OF MENINGITIS
THERE ARE FOUR TYPES OF MENINGITIS
1) BACTERIAL MENINGITIS
- Bacterial meningitis is an inflammatory response to
bacterial infection of the pia-arachnoid and CSF of the
subarachnoid space.
or
- a condition that results in inflammation of the protective
membranes that envelop the brain and spinal cord due to a
bacterial cause
1. Mycobacterium tuberculosis
2. streptococcus pneumonia
3. Haemophilus influenza
4. Streptococcus agalactiaes [group B streptococcus]
5. Neisseria meningitidis [ meningococcus ]
5. 2).VIRAL MENINGITIS
infection of the meninges, which is a thin lining
over the brain and spinal cord.
viral meningitis is most common in children and
babies bcz the immune system of younger people
are as well built.
1. Herpes virus
2. Herpes simplex virus
3. Hiv
4. Mumps virus
5. West nile virus
6. Other also can cause viral meningitis.
6. 3). FUNGAL MENINGITIS
Fungal infection can spread through the blood to
the central nervous system, which made up or
evolve of the spinal cord and brain. When this
occurs, it may cause fungal meningitis, which is an
inflammation of the protective membrane
surrounding the central nervous system.
Fungal meningitis isn’t contagious from person to
person.
It’s life threatening if not treated with an antifungal
medication.
It is less common than the other two infection
it is rare in healthy people but it is more likely in
person who have impaired immune system.
8. 4).NON-INFECTION MENINGITIS
Non infectious meningitis is possible when the fluid
contanis excess white blood cell (indicting
inflammation) and does not contain any bacteria that
could be the cause
then other tests are done to identify infectious
organisms other than bacteria such as viruses and fungi
in the cerebrospinal fluid
No spread person to person contact
1. Nonstroidal anti-inflammatory drugs {NSAIDs}
2. Certain antibiotics
3. Head injury
4. Head surgery
5. Low immune system
6. Cancer
9. ETIOLOGY &
Bacterial infection
Viral infection
Fungal infection
inflammatory diseases
E. coli in neonates
Pneumococcus in children
Meningococcus in adult
10. RISK FACTOR
Sinusitis
Cancer
immunocompromised state
Otitis
paramaningeal infection
head trauma
age extremes
splenectomy
alcoholism
neuro surgical procedure
Infections ( systmic, ex. respiratory)
11. PATHOPHYSIOLOGY OF MENINGITIS
Due to etiology/risk factor
Bacteria enters blood stream/trauma
Enters the mucosal surface
Breakdown of normal barriers
Crosses the blood brain barrier
Proliferates in the CSF
Inflammation of the meninges
Increase in ICP
12. CLINICAL MANIFESTATION
Sudden high fever
Headache
Confusion
Drowsiness
Irritation
Photophobia
Nausea and vomiting
Neck stiffness
Consciousness
Coma in sever cases
Petechial rashes
14. DIAGNOSTIC TEST
P. E.
H. C.
CT – scan
X – ray
CSF culture examination
Gram staining
Blood culture test ( for Bacterial, viral, fungal )
15. MANAGEMENT
1. Medical management
a. Pharmacological management
- antibiotic ( ampicillin, penicillin, amoxycillin )
- some time corticosteroids (dexamethasone)
- antiviral ( tenofovir )
- antifungal ( fluconazole )
- antipyratics ( acetaminophen )
16. B. NON PHARMACOLOGY
- Maintain of fluid electrolyte balance
- Vitamin supplementation
- Head end elevation 30-45 degree
- Emotional support
- Information for continuation of care at home,
follow up
- Rehabilitation