We are responsible for shaping our future through the application of science and technology. While scientific progress is accelerating, cultural, social, and legal systems are lagging behind, which can cause conflicts over new technologies. As our capabilities increase, so too does our responsibility to ensure technologies are developed and applied safely, ethically, and for the benefit of all humanity. We must thoughtfully consider issues like life extension, human enhancement, and artificial intelligence to guide progress in a way that respects human rights and dignity. Overall, we need new cultural paradigms that embrace ongoing change and allow society to reap the full benefits of scientific knowledge.